Embryology and Histology of The Parathyroid Glands

Abstract

The parathyroid glands are endocrine organs that regulate serum calcium and bone metabolism. These glands are endodermal in origin. They develop from the third and fourth pharyngeal sacs between the fifth and 12th weeks of gestation. Chief cells and oxyphil cells are two parenchymal epithelial cells. Chief cells secrete parathormone that are the predominant and abundant cells in the parathyroid glands. Oxyphil cells are thought to be degenerating chief cells. Except these cells, there are many fat cells in the stroma and parenchyma that appears in adolescent period and increase with age.

Keywords

• chief cells
• oxyphil cells
• parathyroid

Paratiroid Bezlerinin Embriyolojisi ve Histolojisi

Öz

Paratiroid bezleri serum kalsiyumunu ve kemik metabolizmasını düzenleyen endokrin organlardır. Bu bezler endodermal kökenlidir. Gebeliğin beşinci ve 12. haftaları arasında, üçüncü ve dördüncü faringeal keselerden gelişirler. Şef hücreler ve oksifil hücreler, iki parankimal epitel hücresidir. Şef hücreler, paratiroid bezlerinde baskın ve bol miktarda bulunan hücrelerdir ve parathormon salgılar. Oxyphil hücrelerinin dejenere olan şef hücreleri olduğu düşünülmektedir. Bu hücrelerin dışında, stroma ve parankimde, adölesan dönemde ortaya çıkan ve yaşla birlikte artan çok sayıda yağ hücresi bulunur.

Anahtar Kelimeler

• chief cells
• oxyphil cells
• parathyroid

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