Bir Opioid Olan Tramadolün Farmakolojik Etkileri

Burçin Ün; Ayper Pekmezekmek; Betül Kalay; Özlem Özü; Ata Seçilmiş

doi:10.17827/aktd.1305162

TR EN

Bir Opioid Olan Tramadolün Farmakolojik Etkileri

Öz

Tramadol, yapıca kodeine benzeyen, sentetik bir opiod olan santral etkili analjeziktir. Analjezik etkisini selektif zayıf µ-opioid reseptör affinitesiyle göstermektedir. Ayrıca gebelerde kullanımı da yaygındır. Akut ve kronik ağrı tedavilerinde sıklıkla tercih edilen bir ilaç olmasına rağmen son zamanlarda kötüye kullanımı da giderek artmaktadır. Tramadol, rahatlatıcı bir etkiye de sahip olup diğer opioidlere göre bağımlılık yapma potansiyeli daha düşüktür. Gebelerde analjezik etkisi nedeniyle yaygın olarak kullanıldığı halde embriyoteratonejitesi hakkında yeterli çalışma yapılmamıştır.

Anahtar Kelimeler

Bağımlılık , Farmakolojik etkiler , Gebelik , Opioid , Tramadol

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Sağlık Kurumları Yönetimi

Bölüm

Derleme

Yazarlar

Burçin Ün ^*
0000-0002-8065-8165
Türkiye

Ayper Pekmezekmek
0000-0002-3028-605X
Türkiye

Betül Kalay
0009-0009-4085-3423
Türkiye

Özlem Özü
0000-0001-6297-9865
Türkiye

Ata Seçilmiş
0000-0002-7224-8764
Türkiye

Yayımlanma Tarihi

31 Aralık 2023

Gönderilme Tarihi

29 Mayıs 2023

Kabul Tarihi

15 Kasım 2023

Yayımlandığı Sayı

Yıl 1970 Cilt: 32 Sayı: 4

DOI

https://doi.org/10.17827/aktd.1305162

IZ

https://izlik.org/JA46BF84NG

AMA

1.Ün B, Pekmezekmek A, Kalay B, Özü Ö, Seçilmiş A. Bir Opioid Olan Tramadolün Farmakolojik Etkileri. aktd. 2023;32(4):206-214. doi:10.17827/aktd.1305162

Bir Opioid Olan Tramadolün Farmakolojik Etkileri

Bir Opioid Olan Tramadolün Farmakolojik Etkileri

Öz

Anahtar Kelimeler

Pharmacological Effects of Tramadol, an Opioid

Abstract

Keywords

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

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