Opioid Kullanım Bozukluğu ve Farmakolojik Tedavisinde Kullanılan İlaçlar

Peyman Ertuğ; Serkan Ecemiş

doi:10.17827/aktd.1492043

TR EN

Opioid Kullanım Bozukluğu ve Farmakolojik Tedavisinde Kullanılan İlaçlar

Öz

Opioid kullanım bozukluğu dünyada önemli bir şekilde morbidite ve mortalite kaynağı olmaya devam etmektedir. Farmakoterapi, opioid yoksunluk semptomlarını hafifletmek, nüksetmeyi azaltmak ve uzun vadeli iyileşmeyi sağlamak amacıyla opioid kullanım bozukluğunun tedavisinde önemli rol oynamaktadır. Metadon, buprenorfin, nalokson, naltrekson, klonidin ile yapılan tedavilerin, opioid kullanım bozukluğunu düzeltmede, bağımlılığın tedavisinde ve aşırı dozdan ölümleri azaltmada etkili olduğu gösterilmiştir. Bu derlemede, opioid bağımlılığının biyolojik mekanizmaları, opioid kullanım bozukluğunun tedavisinde kullanılan farmakolojik ajanların farmakokinetiği, farmakodinamiği, endikasyonları ve yan etkileri hakkında bilgi verilmektedir.

Anahtar Kelimeler

opioidler , opioid kullanım bozukluğu , farmakoterapiler , nalokson , buprenorfin , naltrekson , metadon , klonidin

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Sinirbilim (Diğer)

Bölüm

Derleme

Yazarlar

Peyman Ertuğ ^*
0000-0002-8911-2935
Türkiye

Serkan Ecemiş
0009-0007-1803-198X
Türkiye

Yayımlanma Tarihi

31 Aralık 2024

Gönderilme Tarihi

29 Mayıs 2024

Kabul Tarihi

18 Kasım 2024

Yayımlandığı Sayı

Yıl 2024 Cilt: 33 Sayı: 4

DOI

https://doi.org/10.17827/aktd.1492043

IZ

https://izlik.org/JA37RC46GC

AMA

1.Ertuğ P, Ecemiş S. Opioid Kullanım Bozukluğu ve Farmakolojik Tedavisinde Kullanılan İlaçlar. aktd. 2024;33(4):287-293. doi:10.17827/aktd.1492043

Opioid Kullanım Bozukluğu ve Farmakolojik Tedavisinde Kullanılan İlaçlar

Opioid Kullanım Bozukluğu ve Farmakolojik Tedavisinde Kullanılan İlaçlar

Öz

Anahtar Kelimeler

Opioid Use Disorder and Drugs Used in Pharmacological Treatment

Abstract

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster