Application of Meta-analysis for Determining Cancer Biomarkers
Abstract
The health care professionals are facing the challenge to combine and translate the findings from a plethora of, often conflicting, clinical trials or clinical studies in order to reach an evidence-based decision. The application of a meta-analytical approach in the medical field allows the systematic synthesis and assessment of the results across studies to draw conclusions about the main body of the research, such as a more accurate estimate of treatment effect or determining disease risk factors. Herein, we review the advantages and the basic steps of meta-analysis towards the identification of powerful cancer biomarkers.
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