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Hastanelerde İlaç Uzlaşısının Önemi

Yıl 2026, Cilt: 35 Sayı: 1, 43 - 57, 02.03.2026
https://izlik.org/JA88PN83YY

Öz

Bu çalışma, hastanelerde ilaç uzlaşısı uygulamalarının hasta güvenliği üzerindeki etkilerini, sağlık hizmetlerinin kalitesine katkılarını ve bu sürecin uygulanabilirliğini incelemek amacıyla hazırlanmıştır. İlaç uzlaşısı; hastaların hastaneye yatışı, birimler arası transferi ve taburculuk gibi bakım geçişlerinde, mevcut ilaç kullanım bilgileri ile yeni tedavi planlarının karşılaştırılarak olası tutarsızlıkların önlenmesini hedefleyen sistematik bir yaklaşımdır. Araştırma kapsamında, ilaç uzlaşısı sürecinin tanımı, temel ilkeleri, klinik eczacının rolü ve bu uygulamanın ulusal ve uluslararası düzeydeki örnekleri değerlendirilmiştir. Polifarmasi, ilaç-ilaç etkileşimleri ve yanlış doz uygulamaları gibi yaygın ilaç hatalarının önlenmesinde uzlaşı sürecinin sağladığı katkılar detaylı biçimde ele alınmıştır. Ayrıca, hasta güvenliği ve sağlıkta maliyet etkinlik açısından ilaç uzlaşısının taşıdığı stratejik önem vurgulanmıştır. Bu çalışma, hastanelerde ilaç güvenliğinin artırılmasında ilaç uzlaşısının temel bir araç olarak değerlendirilmesi gerektiğini ortaya koymakta ve ilaç uzlaşısı uygulamalarının sağlık sistemine entegrasyonu sürecinde karşılaşılan zorluklara da ışık tutarak, etkin bir uygulama için gerekli yapısal ve organizasyonel önerilere yer vermektedir.

Kaynakça

  • 1. WHO Global Patient Safety Challenge (2017). Medication without harm. World Health Organization.
  • 2. Almanasreh E, Moles R, Chen TF. The medication reconciliation process and classification of discrepancies: a systematic review. Br J Clin Pharmacol. 2016;82:645-58.
  • 3. Cornish PL, Knowles SR, Marchesano R, Tam V, Shadowitz S, Juurlink DN et al. Unintended medication discrepancies at the time of hospital admission. Arch Intern Med. 2005;165:424-9.
  • 4. Penm J, Vaillancourt R, Pouliot A. Defining and identifying concepts of medication reconciliation: an international pharmacy perspective. Res Social Adm Pharm. 2019;15:632-40.
  • 5. Zeitouni R, Saha A, Gettys KE, Avey K, Burdon TD. Improving transition of care for patients with high risk for readmission. J Gen Intern Med. 2014;29:486-7.
  • 6. Enver C, Şengel BE, Sancar M, Korten V, Okuyan B. Medication reconciliation service in hospitalized patients with infectious diseases during coronavirus disease 2019 pandemic: An observational study. Turk J Pharm Sci. 2023;20(4).
  • 7. Mueller SK, Sponsler KC, Kripalani S, Schnipper JL. Hospital based medication reconciliation practices: a systematic review. Arch Intern Med. 2012;172:1057-69.
  • 8. Viktil KK, Blix HS, Moger TA, Reikvam A. Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug related problems. Br J Clin Pharmacol. 2007;63:187-95.
  • 9. Blozik E, Rapold R, Von Overbeck J, Reich O. Polypharmacy and potentially inappropriate medication in the adult, community dwelling population in Switzerland. Drugs & Aging. 2013;30:561-8.
  • 10. Bjerrum L, Søgaard J, Hallas J, Kragstrup J. Polypharmacy: correlations with sex, age and drug regimen-a prescription database study. Eur J Clin Pharmacol. 1998;54:197-202.
  • 11. Shah BM, Hajjar ER. Polypharmacy, adverse drug reactions, and geriatric syndromes. Clin Geriatr Med. 2012;28:173-86.
  • 12. Masnoon N, Shakib S, Kalisch-Ellett L, Caughey GE. What is polypharmacy? A systematic review of definitions. BMC Geriatrics. 2017;17:230.
  • 13. Hermann M, Carstens N, Kvinge L, Fjell A, Wennersberg M, Folleso K et al. Polypharmacy and potential drug-drug interactions in home dwelling older people-a cross sectional study. J Multidiscip Healthc. 2021;2021:589-97.
  • 14. Wolff J, Hefner G, Normann C, Kaier K, Binder H, Hiemke C et al. Polypharmacy and the risk of drug-drug interactions and potentially inappropriate medications in hospital psychiatry. Pharmacoepidemiol Drug Saf. 2021;30:1258-68.
  • 15. Marengoni A, Onder G. Guidelines, polypharmacy, and drug drug interactions in patients with multimorbidity. BMJ. 2015.
  • 16. Ernawati DK, Lee YP, Hughes JD. Nature and frequency of medication errors in a geriatric ward: an Indonesian experience. Ther Clin Risk Manag. 2014:413-21.
  • 17. Härkänen M, Vehviläinen-Julkunen K, Murrells T, Rafferty AM, Franklin BD. Medication administration errors and mortality: Incidents reported in England and Wales between 2007 ̶ 2016. Res Social Adm Pharm. 2019;15:858-63.
  • 18. Who Challenge W. Medication without harm. World Health Organization. 2017 2017.
  • 19. Aitken M, Gorokhovich L. Advancing the responsible use of medicines: applying levers for change. 2012 2012.
  • 20. Choi I, Lee S-M, Flynn L, Kim C-m, Lee S, Kim N-K, et al. Incidence and treatment costs attributable to medication errors in hospitalized patients. Research in Social and Administrative Pharmacy. 2016;12:428-37.
  • 21. Al Worafi YM. Medication errors. In Drug Safety in Developing Countries. Academic Press. 2020;59-71.
  • 22. World Health Organization (2016). Medication errors. In Medication Errors [ Medication safety in transitions of care: technical report2019 2019.
  • 23. Organization WH. Medication safety in transitions of care: technical report. Geneva: World Health Organization; 2019 2019. Report No.: WHO/UHC/SDS/2019.9.
  • 24. Eng JA, Steinman MA. Changing chronic medications in hospitalized patients-bridging the inpatient outpatient divide. J Hosp Med. 2014;9(5).
  • 25. Meguerditchian AN, Krotneva S, Reidel K, Huang A, Tamblyn R. Medication reconciliation at admission and discharge: a time and motion study. BMC Health Serv Res. 2013;13:1-10.
  • 26. Gleason KM, Groszek JM, Sullivan C, Rooney D, Barnard C, Noskin GA. Reconciliation of discrepancies in medication histories and admission orders of newly hospitalized patients. Am J Health Syst Pharm. 2004(16).
  • 27. Kwan Y, Fernandes OA, Nagge JJ, Wong GG, Huh JH, Hurn DA et al. Pharmacist medication assessments in a surgical preadmission clinic. Arch Intern Med. 2007;167:1034-40.
  • 28. Abdulghani KH, Aseeri MA, Mahmoud A, Abulezz R. The impact of pharmacist-led medication reconciliation during admission at tertiary care hospital. International Journal of Clinical Pharmacy. 2018;40:196-201.
  • 29. Mogaka B, Clary D, Hong C, Farris C, Perez S. Medication reconciliation in the emergency department performed by pharmacists. Proc (Bayl Univ Med Cent). 2018;31:436-8.
  • 30. Cadman B, Wright D, Bale A, Barton G, Desborough J, Hammad EA et al. Pharmacist provided medicines reconciliation within 24 hours of admission and on discharge: a randomised controlled pilot study. BMJ Open. 2017;7:e013647.
  • 31. Lee JY, Leblanc K, Fernandes OA, Huh JH, Wong GG, Hamandi B et al. Medication reconciliation during internal hospital transfer and impact of computerized prescriber order entry. Ann Pharmacother. 2010;44:1887-95.
  • 32. Marinović I, Bačić Vrca V, Samardžić I, Marušić S, Grgurević I, Papić I, et al. Impact of an integrated medication reconciliation model led by a hospital clinical pharmacist on the reduction of post-discharge unintentional discrepancies. J Clin Pharm Ther. 2021;46:1326-33.
  • 33. Jošt M, Knez L, Mrhar A, Kerec Kos M. Adverse drug events during transitions of care : Randomized clinical trial of medication reconciliation at hospital admission. Wien Klin Wochenschr. 2022;134:130-8.
  • 34. Lee S, Yu YM, Han E, Park MS, Lee JH, Chang MJ. Effect of Pharmacist-Led Intervention in Elderly Patients through a Comprehensive Medication Reconciliation: A Randomized Clinical Trial. Yonsei Med J. 2023;64:336-43.
  • 35. Kripalani S, Roumie CL, Dalal AK, Cawthon C, Businger A, Eden SK et al. Effect of a pharmacist intervention on clinically important medication errors after hospital discharge: a randomized trial. Ann Intern Med. 2012;157:1-10.
  • 36. Polinski JM, Moore JM, Kyrychenko P, Gagnon M, Matlin OS, Fredell JW et al. An Insurer's Care Transition Program Emphasizes Medication Reconciliation, Reduces Readmissions And Costs. Health Aff (Millwood). 2016;35:1222-9.
  • 37. Hellström LM, Bondesson A, Höglund P, Midlöv P, Holmdahl L, Rickhag E et al. Impact of the Lund Integrated Medicines Management (LIMM) model on medication appropriateness and drug-related hospital revisits. Eur J Clin Pharmacol. 2011;67:741-52.
  • 38. Hammad EA, Khaled F, Shafaamri M, Amireh B, Arabyat R, Abu-Farha RK. Impacts of pharmacist-led medication reconciliation on discrepancies and 30-days post-discharge health services utilization in elderly Jordanians. PLoS One. 2025;20:e0320699.
  • 39. Salanitro AH, Osborn CY, Schnipper JL, Roumie CL, Labonville S, Johnson DC et al. Effect of patient- and medication-related factors on inpatient medication reconciliation errors. J Gen Intern Med. 2012;27:924-32.
  • 40. Bolas H, Brookes K, Scott M, McElnay J. Evaluation of a hospital-based community liaison pharmacy service in Northern Ireland. Pharm World Sci. 2004;26:114-20.
  • 41. Gray S, Urwin M, Woolfrey S, Harrington B, Cox J. Copying hospital discharge summaries to practice pharmacists: does this help implement treatment plans? Qual Prim Care. 2008;16:327-34.
  • 42. Gleason KM, McDaniel MR, Feinglass J, Baker DW, Lindquist L, Liss D et al. Results of the Medications at Transitions and Clinical Handoffs (MATCH) study: an analysis of medication reconciliation errors and risk factors at hospital admission. J Gen Intern Med. 2010;25:441-7.
  • 43. Joseph AG, Saji S, Kumbhar AN, Shivakumar G, Bhandari R, Ganachari MS. Pharmacists' Medication Reconciliation Interventions During Admission and Transfer from an Emergency Department at a Tertiary Care Hospital: A Randomized Pilot Study and Evaluation of Physician and Patient Perceptions. Curr Drug Saf. 2024;19):368-76.
  • 44. Vega TG, Sierra-Sánchez JF, Martínez-Bautista MJ, García-Martín F, Suárez-Carrascosa F, Baena-Cañada JM. Medication Reconciliation in Oncological Patients: A Randomized Clinical Trial. J Manag Care Spec Pharm. 2016;22:734-40.
  • 45. Sancar M, Özker PD, Turan B, Okuyan B. Hastane yatışında eczacı tarafından yürütülen ilaç mutabakatı programının değerlendirilmesi. Clin Exp Health Sci. 2014;4(4).
  • 46. van Sluisveld N, Zegers M, Natsch S, Wollersheim H. Medication reconciliation at hospital admission and discharge: insufficient knowledge, unclear task reallocation and lack of collaboration as major barriers to medication safety. BMC Health Serv Res. 2012;12:170.
  • 47. Rogers G, Alper E, Brunelle D, Federico F, Fenn CA, Leape LL et al. Reconciling medications at admission: safe practice recommendations and implementation strategies. Jt Comm J Qual Patient Saf. 2006;32:37-50.
  • 48. Rojas-Ocaña MJ, Teresa-Morales C, Ramos-Pichardo JD, Araujo-Hernández M. Barriers and Facilitators of Communication in the Medication Reconciliation Process during Hospital Discharge: Primary Healthcare Professionals' Perspectives. Healthcare (Basel). 2023;11:1495. doi:10.3390/healthcare11101495.
  • 49. Linden-Lahti C, Holmström AR, Pennanen P, Airaksinen M. Facilitators and barriers in implementing medication safety practices across hospitals within 11 European Union countries. Pharm Pract (Granada). 2019;17:1583.
  • 50. Schnipper JL, Hamann C, Ndumele CD, Liang CL, Carty MG, Karson AS et al. Effect of an electronic medication reconciliation application and process redesign on potential adverse drug events: a cluster-randomized trial. Arch Intern Med. 2009;169:771-80.
  • 51. Manias E, Cranswick N, Newall F, Rosenfeld E, Weiner C, Williams A, et al. Medication error trends and effects of person-related, environment-related and communication-related factors on medication errors in a paediatric hospital. J Paediatr Child Health. 2019;55:320-6.
  • 52. Bishop MA, Cohen BA, Billings LK, Thomas EV. Reducing errors through discharge medication reconciliation by pharmacy services. Am J Health Syst Pharm. 2015;72:120-6.
  • 53. Gillespie U, Alassaad A, Henrohn D, Garmo H, Udenaes H, Toss M, et al. A comprehensive pharmacist intervention to reduce morbidity in patients 80 years or older: a randomized controlled trial. Arch Intern Med. 2009;169:894-900.
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  • 58. Varkey P, Cunningham J, Meara O, Bonacci J, Desai R, Sheeler N. Multidisciplinary approach to inpatient medication reconciliation in an academic setting. Am J Health Syst Pharm. 2007;64:850-4.
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The Importance of Medication Reconciliation in Hospitals

Yıl 2026, Cilt: 35 Sayı: 1, 43 - 57, 02.03.2026
https://izlik.org/JA88PN83YY

Öz

This study aims to examine the impact of medication reconciliation practices in hospitals on patient safety, the quality of healthcare services, and the feasibility of implementation. Medication reconciliation is a systematic process that involves comparing a patient’s current medication usage with newly prescribed treatments during transitions in care, such as hospital admission, intra-hospital transfers, and discharge, in order to prevent possible discrepancies. Within the scope of the research, the definition, fundamental principles, and implementation steps of medication reconciliation, along with the role of clinical pharmacists, have been evaluated through national and international practices. The contribution of this process in preventing common medication errors such as polypharmacy, drug-drug interactions, and incorrect dosing has been discussed in detail. The strategic importance of medication reconciliation in terms of improving patient safety and ensuring cost-effective healthcare is also emphasized. Furthermore, this study addresses the challenges faced in integrating medication reconciliation into healthcare systems and proposes organizational and structural strategies for effective implementation. The findings indicate that medication reconciliation should be regarded as a key tool in enhancing medication safety in hospitals.

Kaynakça

  • 1. WHO Global Patient Safety Challenge (2017). Medication without harm. World Health Organization.
  • 2. Almanasreh E, Moles R, Chen TF. The medication reconciliation process and classification of discrepancies: a systematic review. Br J Clin Pharmacol. 2016;82:645-58.
  • 3. Cornish PL, Knowles SR, Marchesano R, Tam V, Shadowitz S, Juurlink DN et al. Unintended medication discrepancies at the time of hospital admission. Arch Intern Med. 2005;165:424-9.
  • 4. Penm J, Vaillancourt R, Pouliot A. Defining and identifying concepts of medication reconciliation: an international pharmacy perspective. Res Social Adm Pharm. 2019;15:632-40.
  • 5. Zeitouni R, Saha A, Gettys KE, Avey K, Burdon TD. Improving transition of care for patients with high risk for readmission. J Gen Intern Med. 2014;29:486-7.
  • 6. Enver C, Şengel BE, Sancar M, Korten V, Okuyan B. Medication reconciliation service in hospitalized patients with infectious diseases during coronavirus disease 2019 pandemic: An observational study. Turk J Pharm Sci. 2023;20(4).
  • 7. Mueller SK, Sponsler KC, Kripalani S, Schnipper JL. Hospital based medication reconciliation practices: a systematic review. Arch Intern Med. 2012;172:1057-69.
  • 8. Viktil KK, Blix HS, Moger TA, Reikvam A. Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug related problems. Br J Clin Pharmacol. 2007;63:187-95.
  • 9. Blozik E, Rapold R, Von Overbeck J, Reich O. Polypharmacy and potentially inappropriate medication in the adult, community dwelling population in Switzerland. Drugs & Aging. 2013;30:561-8.
  • 10. Bjerrum L, Søgaard J, Hallas J, Kragstrup J. Polypharmacy: correlations with sex, age and drug regimen-a prescription database study. Eur J Clin Pharmacol. 1998;54:197-202.
  • 11. Shah BM, Hajjar ER. Polypharmacy, adverse drug reactions, and geriatric syndromes. Clin Geriatr Med. 2012;28:173-86.
  • 12. Masnoon N, Shakib S, Kalisch-Ellett L, Caughey GE. What is polypharmacy? A systematic review of definitions. BMC Geriatrics. 2017;17:230.
  • 13. Hermann M, Carstens N, Kvinge L, Fjell A, Wennersberg M, Folleso K et al. Polypharmacy and potential drug-drug interactions in home dwelling older people-a cross sectional study. J Multidiscip Healthc. 2021;2021:589-97.
  • 14. Wolff J, Hefner G, Normann C, Kaier K, Binder H, Hiemke C et al. Polypharmacy and the risk of drug-drug interactions and potentially inappropriate medications in hospital psychiatry. Pharmacoepidemiol Drug Saf. 2021;30:1258-68.
  • 15. Marengoni A, Onder G. Guidelines, polypharmacy, and drug drug interactions in patients with multimorbidity. BMJ. 2015.
  • 16. Ernawati DK, Lee YP, Hughes JD. Nature and frequency of medication errors in a geriatric ward: an Indonesian experience. Ther Clin Risk Manag. 2014:413-21.
  • 17. Härkänen M, Vehviläinen-Julkunen K, Murrells T, Rafferty AM, Franklin BD. Medication administration errors and mortality: Incidents reported in England and Wales between 2007 ̶ 2016. Res Social Adm Pharm. 2019;15:858-63.
  • 18. Who Challenge W. Medication without harm. World Health Organization. 2017 2017.
  • 19. Aitken M, Gorokhovich L. Advancing the responsible use of medicines: applying levers for change. 2012 2012.
  • 20. Choi I, Lee S-M, Flynn L, Kim C-m, Lee S, Kim N-K, et al. Incidence and treatment costs attributable to medication errors in hospitalized patients. Research in Social and Administrative Pharmacy. 2016;12:428-37.
  • 21. Al Worafi YM. Medication errors. In Drug Safety in Developing Countries. Academic Press. 2020;59-71.
  • 22. World Health Organization (2016). Medication errors. In Medication Errors [ Medication safety in transitions of care: technical report2019 2019.
  • 23. Organization WH. Medication safety in transitions of care: technical report. Geneva: World Health Organization; 2019 2019. Report No.: WHO/UHC/SDS/2019.9.
  • 24. Eng JA, Steinman MA. Changing chronic medications in hospitalized patients-bridging the inpatient outpatient divide. J Hosp Med. 2014;9(5).
  • 25. Meguerditchian AN, Krotneva S, Reidel K, Huang A, Tamblyn R. Medication reconciliation at admission and discharge: a time and motion study. BMC Health Serv Res. 2013;13:1-10.
  • 26. Gleason KM, Groszek JM, Sullivan C, Rooney D, Barnard C, Noskin GA. Reconciliation of discrepancies in medication histories and admission orders of newly hospitalized patients. Am J Health Syst Pharm. 2004(16).
  • 27. Kwan Y, Fernandes OA, Nagge JJ, Wong GG, Huh JH, Hurn DA et al. Pharmacist medication assessments in a surgical preadmission clinic. Arch Intern Med. 2007;167:1034-40.
  • 28. Abdulghani KH, Aseeri MA, Mahmoud A, Abulezz R. The impact of pharmacist-led medication reconciliation during admission at tertiary care hospital. International Journal of Clinical Pharmacy. 2018;40:196-201.
  • 29. Mogaka B, Clary D, Hong C, Farris C, Perez S. Medication reconciliation in the emergency department performed by pharmacists. Proc (Bayl Univ Med Cent). 2018;31:436-8.
  • 30. Cadman B, Wright D, Bale A, Barton G, Desborough J, Hammad EA et al. Pharmacist provided medicines reconciliation within 24 hours of admission and on discharge: a randomised controlled pilot study. BMJ Open. 2017;7:e013647.
  • 31. Lee JY, Leblanc K, Fernandes OA, Huh JH, Wong GG, Hamandi B et al. Medication reconciliation during internal hospital transfer and impact of computerized prescriber order entry. Ann Pharmacother. 2010;44:1887-95.
  • 32. Marinović I, Bačić Vrca V, Samardžić I, Marušić S, Grgurević I, Papić I, et al. Impact of an integrated medication reconciliation model led by a hospital clinical pharmacist on the reduction of post-discharge unintentional discrepancies. J Clin Pharm Ther. 2021;46:1326-33.
  • 33. Jošt M, Knez L, Mrhar A, Kerec Kos M. Adverse drug events during transitions of care : Randomized clinical trial of medication reconciliation at hospital admission. Wien Klin Wochenschr. 2022;134:130-8.
  • 34. Lee S, Yu YM, Han E, Park MS, Lee JH, Chang MJ. Effect of Pharmacist-Led Intervention in Elderly Patients through a Comprehensive Medication Reconciliation: A Randomized Clinical Trial. Yonsei Med J. 2023;64:336-43.
  • 35. Kripalani S, Roumie CL, Dalal AK, Cawthon C, Businger A, Eden SK et al. Effect of a pharmacist intervention on clinically important medication errors after hospital discharge: a randomized trial. Ann Intern Med. 2012;157:1-10.
  • 36. Polinski JM, Moore JM, Kyrychenko P, Gagnon M, Matlin OS, Fredell JW et al. An Insurer's Care Transition Program Emphasizes Medication Reconciliation, Reduces Readmissions And Costs. Health Aff (Millwood). 2016;35:1222-9.
  • 37. Hellström LM, Bondesson A, Höglund P, Midlöv P, Holmdahl L, Rickhag E et al. Impact of the Lund Integrated Medicines Management (LIMM) model on medication appropriateness and drug-related hospital revisits. Eur J Clin Pharmacol. 2011;67:741-52.
  • 38. Hammad EA, Khaled F, Shafaamri M, Amireh B, Arabyat R, Abu-Farha RK. Impacts of pharmacist-led medication reconciliation on discrepancies and 30-days post-discharge health services utilization in elderly Jordanians. PLoS One. 2025;20:e0320699.
  • 39. Salanitro AH, Osborn CY, Schnipper JL, Roumie CL, Labonville S, Johnson DC et al. Effect of patient- and medication-related factors on inpatient medication reconciliation errors. J Gen Intern Med. 2012;27:924-32.
  • 40. Bolas H, Brookes K, Scott M, McElnay J. Evaluation of a hospital-based community liaison pharmacy service in Northern Ireland. Pharm World Sci. 2004;26:114-20.
  • 41. Gray S, Urwin M, Woolfrey S, Harrington B, Cox J. Copying hospital discharge summaries to practice pharmacists: does this help implement treatment plans? Qual Prim Care. 2008;16:327-34.
  • 42. Gleason KM, McDaniel MR, Feinglass J, Baker DW, Lindquist L, Liss D et al. Results of the Medications at Transitions and Clinical Handoffs (MATCH) study: an analysis of medication reconciliation errors and risk factors at hospital admission. J Gen Intern Med. 2010;25:441-7.
  • 43. Joseph AG, Saji S, Kumbhar AN, Shivakumar G, Bhandari R, Ganachari MS. Pharmacists' Medication Reconciliation Interventions During Admission and Transfer from an Emergency Department at a Tertiary Care Hospital: A Randomized Pilot Study and Evaluation of Physician and Patient Perceptions. Curr Drug Saf. 2024;19):368-76.
  • 44. Vega TG, Sierra-Sánchez JF, Martínez-Bautista MJ, García-Martín F, Suárez-Carrascosa F, Baena-Cañada JM. Medication Reconciliation in Oncological Patients: A Randomized Clinical Trial. J Manag Care Spec Pharm. 2016;22:734-40.
  • 45. Sancar M, Özker PD, Turan B, Okuyan B. Hastane yatışında eczacı tarafından yürütülen ilaç mutabakatı programının değerlendirilmesi. Clin Exp Health Sci. 2014;4(4).
  • 46. van Sluisveld N, Zegers M, Natsch S, Wollersheim H. Medication reconciliation at hospital admission and discharge: insufficient knowledge, unclear task reallocation and lack of collaboration as major barriers to medication safety. BMC Health Serv Res. 2012;12:170.
  • 47. Rogers G, Alper E, Brunelle D, Federico F, Fenn CA, Leape LL et al. Reconciling medications at admission: safe practice recommendations and implementation strategies. Jt Comm J Qual Patient Saf. 2006;32:37-50.
  • 48. Rojas-Ocaña MJ, Teresa-Morales C, Ramos-Pichardo JD, Araujo-Hernández M. Barriers and Facilitators of Communication in the Medication Reconciliation Process during Hospital Discharge: Primary Healthcare Professionals' Perspectives. Healthcare (Basel). 2023;11:1495. doi:10.3390/healthcare11101495.
  • 49. Linden-Lahti C, Holmström AR, Pennanen P, Airaksinen M. Facilitators and barriers in implementing medication safety practices across hospitals within 11 European Union countries. Pharm Pract (Granada). 2019;17:1583.
  • 50. Schnipper JL, Hamann C, Ndumele CD, Liang CL, Carty MG, Karson AS et al. Effect of an electronic medication reconciliation application and process redesign on potential adverse drug events: a cluster-randomized trial. Arch Intern Med. 2009;169:771-80.
  • 51. Manias E, Cranswick N, Newall F, Rosenfeld E, Weiner C, Williams A, et al. Medication error trends and effects of person-related, environment-related and communication-related factors on medication errors in a paediatric hospital. J Paediatr Child Health. 2019;55:320-6.
  • 52. Bishop MA, Cohen BA, Billings LK, Thomas EV. Reducing errors through discharge medication reconciliation by pharmacy services. Am J Health Syst Pharm. 2015;72:120-6.
  • 53. Gillespie U, Alassaad A, Henrohn D, Garmo H, Udenaes H, Toss M, et al. A comprehensive pharmacist intervention to reduce morbidity in patients 80 years or older: a randomized controlled trial. Arch Intern Med. 2009;169:894-900.
  • 54. McDonald HP, Garg AX, Haynes RB. Interventions to enhance patient adherence to medication prescriptions: scientific review. JAMA. 2002;288:2868-79.
  • 55. Cheng A, Kessler D, Mackinnon R, Chang TP, Nadkarni VM, Hunt EA et al. Reporting guidelines for health care simulation research: extensions to the CONSORT and STROBE statements. Guidelines Investigators. 2016;1:1-12.
  • 56. Mouazer A, Dubois S, Léguillon R, Boudegzdame N, Levrard T, Bars YL et al. A randomized simulation trial evaluating ABiMed, a clinical decision support system for medication reviews and polypharmacy management 2024 2024.
  • 57. Stolldorf DP, Ridner SH, Vogus TJ, Roumie CL, Schnipper JL, Dietrich MS et al. Implementation strategies in the context of medication reconciliation: a qualitative study. Implement Sci Commun. 2021;2:63. doi:10.1186/s43058-021-00162-5.
  • 58. Varkey P, Cunningham J, Meara O, Bonacci J, Desai R, Sheeler N. Multidisciplinary approach to inpatient medication reconciliation in an academic setting. Am J Health Syst Pharm. 2007;64:850-4.
  • 59. Yu A, Wei G, Chen F, Wang Z, Fu M, Wang G et al. Study protocol for the evaluation of pharmacist participated medication reconciliation at county hospitals in China: a multicentre, open label, assessor blinded, non randomised, controlled study. BMJ Open. 2022;12:e053741. doi: 10.1136/bmjopen-2021-053741.
  • 60. Huibers CJ, Sallevelt BT, De Groot DA, Boer MJ, Van Campen JP, Davids CJ et al. Conversion of STOPP/START version 2 into coded algorithms for software implementation: a multidisciplinary consensus procedure. Int J Med Inform. 2019;125:110-7.
  • 61. Lang PO, Dramé M, Guignard B, Mahmoudi R, Payot I, Latour J et al. Les critères STOPP/START v2: adaptation en langue française. NPG Neurol Psychiatr Gériatr. 2015;15:323-36.
  • 62. Boussadi A, Caruba T, Karras A, Berdot S, Degoulet P, Durieux P et al. Validity of a clinical decision rule-based alert system for drug dose adjustment in patients with renal failure intended to improve pharmacists’ analysis of medication orders in hospitals. Int J Med Inform. 2013;82:964-72.
  • 63. Marien S, Krug B, Spinewine A. Electronic tools to support medication reconciliation: a systematic review. J Am Med Inform Assoc. 2017;24:227-40.
  • 64. Shahzad Aslam M. The impact of pharmacybernetic in reducing medication error2012. 2012.
  • 65. Lesselroth B, Adams S, Felder R, Dorr DA, Cauthers P, Church V et al. Using consumer based kiosk technology to improve and standardize medication reconciliation in a specialty care setting: the Automated Patient History Intake Device (APHID). Jt Comm J Qual Patient Saf. 2009;35:264-P5.
  • 66. Lesselroth BJ, Felder RS, Adams SM, Cauthers PD, Dorr DA, Wong GJ et al. Design and implementation of a medication reconciliation kiosk: the Automated Patient History Intake Device (APHID). J Am Med Inform Assoc. 2009;16:300-4.
Toplam 66 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Hizmetleri ve Sistemleri (Diğer)
Bölüm Derleme
Yazarlar

Mert Emre Gündoğdu 0009-0009-7337-7688

Sevgin Memili 0009-0000-3480-2296

Nursel Surmelioglu 0000-0001-7758-7100

Gönderilme Tarihi 30 Ağustos 2025
Kabul Tarihi 11 Şubat 2026
Yayımlanma Tarihi 2 Mart 2026
DOI https://doi.org/10.17827/aktd.1773960
IZ https://izlik.org/JA88PN83YY
Yayımlandığı Sayı Yıl 2026 Cilt: 35 Sayı: 1

Kaynak Göster

AMA 1.Gündoğdu ME, Memili S, Surmelioglu N. Hastanelerde İlaç Uzlaşısının Önemi. aktd. 2026;35(1):43-57. doi:10.17827/aktd.1773960