Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri

Özlem Görüroğlu Öztürk

EN TR

Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri

Öz

Doğal öldürücü hücre immünglobulin-benzeri reseptörler (Killer cell immunoglobulin-like receptors, KIR), doğal öldürücü hücrelerin yüzeylerinde eksprese olan ve doğal immünitenin düzenlenmesinde önemli rol oynayan moleküllerdir. KIR’lar 19q13.4 kromozomundaki bir gen demeti tarafından kodlanmaktadır. KIR gen demeti oldukça polimorfiktir, bireysel genler allelik polimorfizm içerirken, bireysel haplotipler gen içeriyi açısından farklılıklar gösterir. Human Lökosit Antijen (HLA) genlerine paralel olan KIR lokusunun polimorfizmleri, immün sistemin dinamik ve gelişen çevreye adaptasyonunu kolaylaştırmaktadır. Bu varyasyon pek çok hastalıkla ilişkilidir. Bu derlemede pek çok hastalıkta ve transplantasyon immünolojisinde önem taşıyan KIR moleküllerinin, biyolojisi ve genetiği konuları ele alınmıştır.

Anahtar Kelimeler

Doğal immunite, HLA, KIR, KIR genleri

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

-

Yazarlar

Özlem Görüroğlu Öztürk Bu kişi benim

Yayımlanma Tarihi

1 Eylül 2011

Gönderilme Tarihi

30 Ekim 2014

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2011 Cilt: 20 Sayı: 3

IZ

https://izlik.org/JA38ZE96TB

APA

Öztürk, Ö. G. (2011). Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri. Arşiv Kaynak Tarama Dergisi, 20(3), 131-144. https://izlik.org/JA38ZE96TB

AMA

1.Öztürk ÖG. Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri. aktd. 2011;20(3):131-144. https://izlik.org/JA38ZE96TB

Chicago

Öztürk, Özlem Görüroğlu. 2011. “Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri”. Arşiv Kaynak Tarama Dergisi 20 (3): 131-44. https://izlik.org/JA38ZE96TB.

EndNote

Öztürk ÖG (01 Eylül 2011) Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri. Arşiv Kaynak Tarama Dergisi 20 3 131–144.

IEEE

[1]Ö. G. Öztürk, “Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri”, aktd, c. 20, sy 3, ss. 131–144, Eyl. 2011, [çevrimiçi]. Erişim adresi: https://izlik.org/JA38ZE96TB

ISNAD

Öztürk, Özlem Görüroğlu. “Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri”. Arşiv Kaynak Tarama Dergisi 20/3 (01 Eylül 2011): 131-144. https://izlik.org/JA38ZE96TB.

JAMA

1.Öztürk ÖG. Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri. aktd. 2011;20:131–144.

MLA

Öztürk, Özlem Görüroğlu. “Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri”. Arşiv Kaynak Tarama Dergisi, c. 20, sy 3, Eylül 2011, ss. 131-44, https://izlik.org/JA38ZE96TB.

Vancouver

1.Özlem Görüroğlu Öztürk. Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri. aktd [Internet]. 01 Eylül 2011;20(3):131-44. Erişim adresi: https://izlik.org/JA38ZE96TB

Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri

Killer Cell Immunoglobulin-Like Receptor Genes

Öz

Anahtar Kelimeler

Doğal Öldürücü Hücre Immunglobulin-Benzeri Reseptör Genleri

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

IZ

Kaynak Göster