İskemik İnme ve Akut Faz Reaktanları

Mustafa Şahan; Salim Satar; A. Filiz Koç; Ahmet Sebe

EN TR

İskemik İnme ve Akut Faz Reaktanları

Öz

İnme olarak tanımlanan serebrovasküler hastalıklar (SVH); ciddi mortalite ve morbiditeye yol açan hastalıklardan biridir. İnme ölüm sebepleri içerisinde üçüncü ve sakatlık yönünden de birinci sırada olan hastalık grubudur. İnmenin % 80-85'ini iskemik inme oluşturur. İnme morbit olabildiği gibi; kişi, aile ve toplum üzerinde psikososyal problemlere yol açar ayrıca, ekonomik yönden de yük teşkil eder.

Anahtar Kelimeler

İnme, Akut Faz Reaktanları, Serebrovasküler Hastalıklar

Kaynakça

Salford LG, Plum F, Berierley JB. Graded hypoxia-oligemia in rat brain. II. Neuropathological alterations and their implications. Arch Neurol, 1973;29:234.
Özbay G. Hemodinamik bozukluklar, tromboz ve şok. In: Kumar V, Cotran RS, Robins SL
(eds). Temel Patoloji. 6
th, İstanbul: Nobel Kitabevleri, 2000: 60.
Touzani O, Young AR. Progressive impairment of brain oxidative metabolism reversed by reperfusion following middle cerebral artery occlusion in anaesthetized baboons. Brain Res.1997:767: 17-25.
Sharp FR, Lu A, Tang Y, Millhorn DE. Multiple molecular penumbras after focal cerebral ischemia. J Cereb Blood Flow Metab. 2000 : 20:1011-1032.
Fishman RA. Brain edema. N Engl J Med, 1975;293:706.
Rothman S. Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death. J Neurosci, 1984; 4: 1884.
Muir KW, Less KR. Clinical experience with excitatory amino acid antagonist drugs. Stroke, 1995; 26: 503. 15
Siejko BK. Pathophysiology and treatment of focal cerebral ischemia. Part II, Mechanisms of damage and treatment. J Neurosurg, 1992; 77:337.

Slivka A, Brannan TS, Weinberger J, et al. Increase in extracellular dopamine in the striatum during cerebral ischemia: a study utilizing cerebral microdialysis. J Nerochem, 1988;50:1714.
Weinberger J, Nieves-Rosa J, Colen G. Nerve terminal damage in cerebral ischemia: protective effect of alpha-methyl-paratyrosine. Stroke, 1985;16:864.
Weinberger J, Nieves-Rosa J. Monoamine neurotransmitters in the evolution in infarction in ischemic striatum: morphologic correlation. J Neurol Trans, 1988;71:133.
Eliasson MJ, Sampei K, Mandir AS, et al. Poly (AD ribose) polymerase gene disruption render mice resistance to cerebral ischemia. Nat Med, 1997; 3:1089.
Siejko BK. Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiologia. J Neurosurgery,1992;77:169.
Brown AW, Brierly JB. The earliest alterations in ratneurones and astrocytes and after anoxia-ischemia. Acta Neuropathol (Berl), 1973;23:9.
Park CK, Nehls DG, Graham DI, et al. The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat. Ann. Neurol, 1988;24:543.
Linnik MD, Miller JA, Sprinkle-Cavolla J, et al. Apoptotic DNA fragmentation in the rat cerebral cortex induced by permanent middle cerebral artery occlusion. Brain Res Mol, 1995;32:116.
Weinberger J, Cohen G, Nieves-Rosa J. Nerve terminal damage in cerebral ischemia: greater suosceptibility of catecholamine nerve terminals relative to serotonin nerve terminals. Stroke, 1983;14:986. Utku U, Çelik Y. Strokta Etyoloji, Sınıflandırma ve Risk Faktörleri. Serebrovasküler Hastalıklar, Edt. Balkan S. Güneş Kitapevi, Antalya, 2005. 57-71.
Kutluk K. İskemik inme. İn: Kutluk K. Klinik yaklaşım ve sınıflama. Nobel Tıp Kitapevi,
İstanbul, 2004:61-73.
Bougousslavsky J, Regli F, Besson G, et al. Early clinical diagnosis of stroke subtypes. Cerebrovasculer Disease .1993; 3:39-44.
Adams Jr HP, Bendixen BH, Capelle J, and TOAST investigators. Classifications of subtype of acute ischemic stroke. Definition for use in multicenter clinical trial. Stroke, 1993;24:35.
Bakaç G. Kardiyoembolik inme. Edt Balkan S. Serebrovasküler Hastalıklar. Güneş Kitapevi, Antalya, 2005, 117-127.
Dora B, Balkan S. Laküner infarktlar. Edt Balkan S. Serebrovasküler Hastalıklar. Güneş
Kitapevi, Antalya, 2005, 103-115.
Steinke W, Ley SC. Lacunar stroke is the major cause of progressive motor deficits. Stroke. 2002; 33: 1510-1516.
Staessen JA, Fagard R, Thijs L, et al. Randomized double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension: The systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Lancet, 1997;350:757.
Curp JD, Pressel SL, Cutler JA, et al. Effect of diuretic-based antihypertensive treatment on cardiovascular disease risk in older diabetic patients with isolated systolic hypertension. Hypertension in the Elderly Program Cooperative Research Group. JAMA, 1996;276:1886.
Kagan A, Poper JS, Rhoads GG. Factors related to stroke incidence in Hawaii, Japanese man: The Honolulu Heart Study. Stroke, 1980;11:14.
UK prospective diabetes study group: Tight blood pressure control risk of macrovascular and microvascular complications in Type-II diabetes: UKPDS, 38. BMJ, 1998;317:703.
Benfante R Yano K, Hwang LJ, et al. Elevated serum cholesterol is a risk factor for both coronary heart disease and thromboembolic stroke in Hawaiian, Japanese man: Implications of shared risk. Stroke, 1994;25:814. Bakar M, Erhan O. Tıkayıcı Tip Serebrovasküler Hastalıklar. Balkan S edt. Serebrovasküler Hastalıklar; Güneş Kitabevi, Antalya, 2005:83-101.
The National Instutite of Nourological Disorders and Stroke rt-PA Stroke Study Group: Tissue plasminogen activator for acut ischemic stroke. N Engl J Med 1995;333:15811587.
Taesdale G, Jennet B: Assessment of coma and impaired comsciosness. A practical scale. Lancet 1974;2:81-84.
Kannel WB, Gordon T, Wolf PA, et all. Hemoglobin and the risk of cerebral infarction: The Franingham study. Stroke, 1972;3:409.
Silverstein A. Thrombotic thrombocytopenic purpura. The initial neurological manifestations. Arch. Neurol, 1968;18:358.
The APASS Group: Anticardiolipin antibodies are an independent risk factor for first ischemic stroke. Neurology, 1993;43:2069.
D’Angelo A, Viggano-D’angelo S, Esmon CT, et al. Acquired deficiencies of protein S. Protein S activity during oral anticoagulation, in liver disease, and in disseminated intravascular coagulation. J. Clin İnvest, 1988;81:1145.
Kohler J, Kasper J, Witt L, et al. Ischemic stroke due top protein C deficiency. Stroke, 1990;21:1077.
Hart FG, Miller VT. Cerebral infarction in young adults. A Practical approach. Stroke, 1983;14:110.
Woo J, Lam CW, Kay R, et al. The influence of hyperglycemia and diabetes mellitus on in mediate and 3-month morbidity and mortality after acute stroke. Arch Neurol, 1990;47:1174.
Wolf PA, Dawber TR, Thomas HE, et al. Epidemiologic assessment of chronic atrial fibrilation and risk of stroke. The Framingham Study. Neurology, 1978;28:973.
Weinberger J, Rothlauf E, Materese E, et al. Noninvasive evaluation of the extracranial carotid arteries in patients with cerebrovascular events and atrial fibrilations. Arch Intern Med, 1998;148:1785.
Dimanth J, Grop D. Electrocardiographic changes and myocardial damage in patients with acute cerbrovascular accidents. Stroke, 1977;8:448.
Hatano S: Variability of the diagnosis of stroke by clinical judgment and by a scoring method. Bull World Health Org. 1976;54:533.
Bamford J. Clinical examination in diagnosis and subclassification of stroke. Lancet, 1992; 339:400.
Önal MZ, Fisher M, Bogousslavsky J. Current Review Of .Cerebrovascular Disease Fourth Edition, edt. Fisher M, Bogousslavsky J, Current Medicine Inc, Philadelphia, 2001, Clinical Evaluation Of Stroke, , 101.
International Stroke Trial Collaborative Group. The International Stroke Trial (IST): A randomized trial of aspirin, subcutaneous heparin, both or neither among 19.435 patients with acute ischemic stroke. Lancet, 1997;349:1569.
CAST (Chinese Acute Stroke Trial) Collaboratice Group. CAST: Randomized placebo control trial of early aspirin use in 200.000 patients with acute ischemic stroke. Lancet, 1997;349:668.
Multicenter Acute Stroke Trial-Italy (MAST-1) Group. Randomized control trial of streptokinase, aspirin, and combination of both in treatment of ischemic stroke. Lancet, 1995;346:1509.
Adams HP, Adams RJ, Brott T, et al. Guidelines for the early management of patients with ischemic stroke. A scientific statement from the stroke council of the American stroke association. Stroke. 2003;34:1056.
Cerebral Embolism Study group. Immediate anticoagulation of embolic stroke: A randomized trial. Stroke, 1983;14:668
Cerebral Embolism TASK Force. Cardiogenic brain embolism. Arch Neurol, 1986;43:7
Kay R, Wong KS, Yu YL, et al. Low molecular weight heparin for the treatment of acute ischemic stroke. N Eng J Med, 1995;333:1588.
The Publications Committee for the trial of ORG 10.712 in Acute Stroke Treatment (TOAST) Investigators. Low molecular weight heparinoid, ORG 10.172 (danaparoid), and outcome after acute ischemic stroke: A randomized controlled trial. JAMA, 1998;279:1265.
Kutluk K. İskemik inme. İn: Kutluk K. Akut Dönemde Antikoagülan Tedavi. Nobel Tıp
Kitapevi, İstanbul, 2004:165-171.
Kutluk K. İskemik inme. İn: Kutluk K. Trombolitik Tedavi. Nobel Tıp Kitapevi, İstanbul, 2004:173-190.
Kutluk K. İskemik inme. İn: Kutluk K. Nöroprotektif Tedavi. Nobel Tıp Kitapevi, İstanbul, 2004: 201-211.
Işıkay CT, Mutluer N. Strok Komplikasyonları. Edt Balkan S. Serebrovasküler Hastalıklar.
Güneş Kitapevi, Antalya, 2005, 345-361.
Dinçel A.S, Sepici V. İnflamasyonun labaratuvar değerlendirilmesi. Çev. Edt. Arasıl T. Kelley
Romatoloji. 7. baskı. Güneş Kitabevi, Ankara, 2006, 720-725.
Camcı C. Granülositler ve monositlerin hastalıkları. Çev. Edt Sağlıker Y. Harrıson İç
Hastalıkları Prensipleri. Nobel tıp kitabevleri. 15. baskı, Adana, 2004,366-374.
Canataroğlu A, Güvenç B. İmmün sistem hastalıkları. Çev. Edt Sağlıker Y. Harrıson İç
Hastalıkları Prensipleri. Nobel tıp kitabevleri. 15. baskı, Adana, 2004,1805-1830.
Bamford J, Sandercock P, Dennis M, Burn J, Warlow C. Classification and natural history of clinical subtypes of cerebral infarction. Lancet 1991; 337:1521-1526 Demir S. Proteinler. Çev. Edt. Aslan T. Tietz Klinik Kimyada Temel İlkeler. 5. baskı. Palme Yayıncılık, Ankara, 2005, 325-351. Öztürk Ş. İnmede biyolojik ve elektrofizyolojik tanı özellikleri. Edt Balkan S. Serebrovasküler Hastalıklar. Güneş Kitapevi, Antalya, 2005, 263-288. Borman P. Fibroblast fonksiyonu ve fibrozis. Çev. Edt. Arasıl T. Kelley Romatoloji. 7. baskı. Güneş Kitabevi, Ankara, 2006, 189-202.
Hakgüder A. Sitokinler. Çev. Edt. Arasıl T. Kelley Romatoloji. 7. baskı. Güneş Kitabevi,
Ankara, 2006, 379-406.

Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

-

Yazarlar

Mustafa Şahan Bu kişi benim

Salim Satar Bu kişi benim

A. Filiz Koç Bu kişi benim

Ahmet Sebe Bu kişi benim

Yayımlanma Tarihi

1 Haziran 2010

Gönderilme Tarihi

30 Ekim 2014

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2010 Cilt: 19 Sayı: 2

IZ

https://izlik.org/JA43AG98NA

AMA

1.Şahan M, Satar S, Koç AF, Sebe A. İskemik İnme ve Akut Faz Reaktanları. aktd. 2010;19(2):85-140. https://izlik.org/JA43AG98NA

İskemik İnme ve Akut Faz Reaktanları

Acute Phase Reactants and Ischemic Stroke

Abstract

Keywords

İskemik İnme ve Akut Faz Reaktanları

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

IZ

Kaynak Göster