Voltaj Kapılı Kalsiyum Kanalları ve Moleküller Özellikleri

Mustafa Emre

doi:10.17827/aktd.329803

EN TR

Voltaj Kapılı Kalsiyum Kanalları ve Moleküller Özellikleri

Öz

Nöron, kas ve endokrin gibi hücrelerden elde edilen elektrobiyofizik kayıtlar, belirgin karakteristiklere sahip ve voltajla aktive edilebilen kalsiyum (Ca2+) akımların olduğunu ortaya koymuştur. Kalsiyum kanalları aktivasyon durumlarına göre düşük voltajla aktive olan (LVA), düşük eşikli kalsiyum kanallar ve yüksek voltajla aktive olan (HVA), yüksek eşikli kalsiyum kanalları olarak kategorize edilmiştir. Voltaj kapılı kalsiyum kanalları; aktivasyon ve inaktivasyon kinetiklerine, iyon özelliklerine, geçirgenliklerine, ilaç ve toksinlere olan duyarlıklarına göre sınıflandırılmışlar. Voltaj bağımlı kalsiyum kanalların dokulardaki dağılımları farklı olup, değişik dokularda değişik karekteristikler gösterirler. Bu derlemede, voltaj kapılı kalsiyum kanallarıyla ilgili mevcut bilgiler özetlenmiştir.

Anahtar Kelimeler

Kalsiyum kanalları,altaile

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Sağlık Kurumları Yönetimi

Bölüm

Derleme

Yazarlar

Mustafa Emre
ÇUKUROVA ÜNİVERSİTESİ, TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ BÖLÜMÜ, BİYOFİZİK ANABİLİM DALI
Türkiye

Yayımlanma Tarihi

31 Mart 2018

Gönderilme Tarihi

20 Temmuz 2017

Kabul Tarihi

10 Eylül 2017

Yayımlandığı Sayı

Yıl 2018 Cilt: 27 Sayı: 1

DOI

https://doi.org/10.17827/aktd.329803

IZ

https://izlik.org/JA33KX54CZ

AMA

1.Emre M. Voltaj Kapılı Kalsiyum Kanalları ve Moleküller Özellikleri. aktd. 2018;27(1):1-17. doi:10.17827/aktd.329803

Cited By

5G (6 GHz) Radyofrekans Elektromanyetik Alanın Sıçan Kan Hücrelerinde Canlılık, Apopitotik ve Nekrotik Hücre Oranına Etkisinin Araştırılması

Arşiv Kaynak Tarama Dergisi

https://doi.org/10.17827/aktd.1221723

KARDİYOVASKÜLER SİSTEM HASTALIKLARINDA KALSİYUM KANAL BLOKÖRLERİ

Ankara Universitesi Eczacilik Fakultesi Dergisi

https://doi.org/10.33483/jfpau.1597966

Voltaj Kapılı Kalsiyum Kanalları ve Moleküller Özellikleri

Voltage-Gated Calcium Channels and Molecular Features

Abstract

Keywords

Voltaj Kapılı Kalsiyum Kanalları ve Moleküller Özellikleri

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster

Cited By

5G (6 GHz) Radyofrekans Elektromanyetik Alanın Sıçan Kan Hücrelerinde Canlılık, Apopitotik ve Nekrotik Hücre Oranına Etkisinin Araştırılması

KARDİYOVASKÜLER SİSTEM HASTALIKLARINDA KALSİYUM KANAL BLOKÖRLERİ