Travma Sonrası Stres Bozukluğunda HPA Ekseninin Disregülasyonu

Miraç Barış Usta

doi:10.17827/aktd.345474

EN TR

Travma Sonrası Stres Bozukluğunda HPA Ekseninin Disregülasyonu

Öz

Endokrinolojik çalışmalar hipotalamik-pitüiter-adrenal ekseninin travma sonrası stres bozukluğu patofizyolojisinde rolünü değerlendirmiş ve modeller oluşturmuştur. Travma sonrası stres bozukluğunda tedavi etkinliğinin izlenmesi başta olmak üzere birçok nedenle biyolojik belirteç arayışı söz konusudur ve travma mağduru hastalarının komorbidite, klinik görünüm, travma etiyolojisi ve travmadan sonra geçen zaman açısından farklılar göstermesi bulgularda çeşitliliklere sebep olmuştur. Bu gözden geçirmede, travma sonrası stres bozukluğunda hipotalamik-pitüiter-adrenal ekseninin fonksiyonu üzerine etkilerini araştıran çalışmaların yöntem ve bulguları gözden geçirilmiştir ve biyolojik terapi belirteci olarak denenen hipotalamik-pitüiter-adrenal ekseninin hormonları ile ilgili bulgular tartışılmıştır.

Anahtar Kelimeler

TSSB,psikoterapi,HPA,biyolojik belirtec

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Sağlık Kurumları Yönetimi

Bölüm

Derleme

Yazarlar

Miraç Barış Usta
Samsun Eğitim ve Araştırma Hastanesi, Çocuk Psikiyatri Kliniği
Türkiye

Yayımlanma Tarihi

31 Mart 2018

Gönderilme Tarihi

20 Ekim 2017

Kabul Tarihi

6 Kasım 2017

Yayımlandığı Sayı

Yıl 2018 Cilt: 27 Sayı: 1

DOI

https://doi.org/10.17827/aktd.345474

IZ

https://izlik.org/JA58YA48MC

AMA

1.Usta MB. Travma Sonrası Stres Bozukluğunda HPA Ekseninin Disregülasyonu. aktd. 2018;27(1):109-125. doi:10.17827/aktd.345474

Travma Sonrası Stres Bozukluğunda HPA Ekseninin Disregülasyonu

Dysregulation of HPA Axis in Post-Traumatic Stress Disorder

Abstract

Keywords

Travma Sonrası Stres Bozukluğunda HPA Ekseninin Disregülasyonu

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

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