Primary Immunodeficiency Diseases and Hematopoietic Stem Cell Transplantation

Yıl 2014, Cilt: 23 Sayı: 1, 108 - 117, 30.10.2014

Ayşe Özkan

https://doi.org/10.17827/aktd.81569

Öz

Hematopoietic stem cell transplantation (HSCT) is the only curative therapy for primary immunodeficiency diseases. Early diagnosis, including prenatally, and early transplantation improve HSCT outcomes. Survival rates improve with advances in the methods of preparing hosts and donor cells, and in supportive and conditioning regimes.

Anahtar Kelimeler

Hematopoietic stem cell transplantation, primary immunodeficiency

Primer İmmün Yetmezlik Hastalıkları ve Hematopoetik Kök Hücre Nakli

Öz

Hematopoetik kök hücre nakli (HKHN) birçok primer immün yetmezlik hastalıkları için tek küratif tedavi yöntemidir. Prenatal dönemi kapsayan erken tanı ve erken nakil ile HKHN ile daha iyi sonuçlar alınmaktadır. Hazırlık ve destek tedavilerinin, alıcıların ve verici hücrelerinin hazırlanmasındaki metodların geliştirilmesi ile sağkalım oranlarında artış olmaktadır.

Anahtar Kelimeler

Hematopoetik kök hücre nakli, primer immün yetmezlik

Kaynakça

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