Derleme
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Hidrojellerin Tıpta Uygulamaları

Yıl 2020, Cilt: 29 Sayı: 2, 129 - 137, 30.06.2020
https://doi.org/10.17827/aktd.603432

Öz




Hidrojeller
“Smart (akıllı)” yapılar olarak tanımlanan ilaç taşınım sistemleri, enjekte
edilebilen polimer sistemleri, doku mühendisliği ve hücre enkapsülasyonu gibi
tıpta yaygın olarak kullanılan polimerlerdir. Hidrojeller suyu yapılarında
tutabilme özellikleri, yumuşak ve esnek yapıda olmaları ile canlı dokulara
büyük benzerlik göstermektedirler. Toksisitesi olmayan, biyolojik olarak
parçalanan ve biyolojik uyum gösterebilen yapıları sebebiyle hidrojellerin
biyomalzeme olarak kullanılması giderek güvenli hale gelmektedir. Aynı zamanda
hidrojellerin kontrollü serbest bırakma mekanizması, ilacın salınım hızını
düzenleyen geleneksel dozaj yöntemleri karşısında birçok avantaj sağlamaktadır.
Bu derlemede genel olarak yara örtüsünde, yanık, anevrizma tedavilerinde, kemik
rejenerasyonunda, kardiyak doku onarım ve rejenerasyonunda, kontrollü ilaç
salınımında, kontakt lenslerde, glokom tedavisinde kullanılan ve biyolojik
araştırmaları devam etmekte olan hidrojellerden bahsedilmektedir.




Teşekkür

Hidrojeller konusuna yönlenmem sürecinde fikirlerini esirgemeyen ve yeni ufuklar açan Doç.Dr. Burcu Okutucu’ya sonsuz teşekkürlerimi sunarım.

Kaynakça

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Toplam 36 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Derleme
Yazarlar

Ayşe Ulusoy 0000-0002-1472-9850

Nurten Dikmen 0000-0002-7411-9640

Yayımlanma Tarihi 30 Haziran 2020
Kabul Tarihi 7 Ekim 2019
Yayımlandığı Sayı Yıl 2020 Cilt: 29 Sayı: 2

Kaynak Göster

AMA Ulusoy A, Dikmen N. Hidrojellerin Tıpta Uygulamaları. aktd. Haziran 2020;29(2):129-137. doi:10.17827/aktd.603432