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Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi

Yıl 2012, Cilt: 1 Sayı: 2, 42 - 45, 01.10.2012

Öz

Çalışmamızda trombosit indekslerinin diyabetik ve diyabetik olmayan geriatrik hemodiyaliz hastalarında karşılaştırılması amaçlandı.Çalışmaya 42 diyabetik 20 erkek, 22 kadın; ortalama yaş: 71,2±5,5 55 diyabetik olmayan 30 erkek, 25 kadın ortalama yaş:72,1±4,6 geriatrik hemodiyaliz hastası alındı. Tam kan sayımı için EDTA'lı tüplere 2ml venöz kan örneği alındı ve trombosit indeksleri [Ortalama Trombosit Hacmi OTH , Trombosit Dağılım Genişliği TDG ] otomatize kan sayım cihazında çalışıldı. OTH ve TDG anlamlı olarak diyabetik hastalarda diyabetik olmayanlara kıyasla yüksek bulundu P

Kaynakça

  • 1. Chu SG, Becker RC, Berger PB, Bhatt DL, Eikelboom JW, Konkle B, Mohler ER, Reilly MP, Berger JS. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and metaanalysis. J Thromb Haemost 2010; 8: 148–56.
  • 2. Sandhaus LM, Meyer P. How useful are CBC and reticulocyte reports to clinicians? Am J Clin Pathol 2002;118(5): 787-93.
  • 3. Bath PM, Butterworth RJ. Platelet size: measurement, physiology and vascular disease. Blood Coagul Fibrinolysis 1996; 7(2): 157-61.
  • 4. Martin TJ, Smith IL, Nolan RD, Dusting GJ. Prostanoids in platelet-vascular interactions. Am J Cardiol 1983; 52(2): 22A-27A.
  • 5. Kishk YT, Trowbridge EA, Martin JF. Platelet volume subpopulations in acute myocardial infarction: an investigation of their homogeneity for smoking, infarct size and site. Clin Sci (Lond) 1985; 68(4): 419-25.
  • 6. Tohgi H, Suzuki H, Tamura K, Kimura B. Platelet volume, aggregation, and adenosine triphosphate release in cerebral thrombosis. Stroke 1991; 22(1): 17-21.
  • 7. Sharpe PC, Trinick T. Mean platelet volume in diabetes mellitus. Q J Med 1993; 86(11): 739-42.
  • 8. Endler G, Klimesch A, Sunder-Plassmann H, et al. Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease. Br J Haematol 2002; 117(2): 399- 404.
  • 9. Jindal S, Gupta S, Gupta R, et al. Platelet indices in diabetes mellitus: indicators of diabetic microvascular complications. Hematology 2011; 16(2): 86-9.
  • 10. American Diabetes Association. Standards of medical care in diabetes-2010. Diab Care 2010; 33(Suppl 1): 11–61.
  • 11. US Renal Data System. USRDS 1994 Annual Data Report. Bethesda, Md: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 1994.
  • 12. McMillan MA, Briggs JD, Junor BJ. Outcome of renal replacement treatment in patients with diabetes mellitus. BMJ 1990; 301: 540 –4.
  • 13. Hirschl MM, Heinz G, Sunder-Plassmann G, Derfler K. Renal replacement therapy in type 2 diabetic patients: 10 years’ experience. Am J Kidney Dis 1992; 20: 564 –8.
  • 14. Rischen-Vos J, van der Woude FJ, Tegzess AM, et al. Increased morbidity and mortality in patients with diabetes mellitus after kidney transplantation as compared with non-diabetic patients. Nephrol Dial Transplant 1992; 7: 433–7.
  • 15. USRDS 2007 Annual Data Report: Atlas of Chronic Kidney Disease And End-Stage Renal Disease in the United States. Volume II Reference Tables. Bethesda, MD: National Kidney and Urologic Diseases Information Clearinghouse, 2007.
  • 16. USRDS 2007 Annual Data Report: Atlas of Chronic Kidney Disease And End-Stage Renal Disease in the United States. Volume 1. Bethesda, MD: National Kidney and Urologic Diseases Information Clearinghouse, 2007.
  • 17. Gritters-van den Oever M, Schoorl M, Schoorl M, Bartels PC, Grooteman MP, Nubé MJ. The role of the extracorporeal circuit in the trapping and degranulation of platelets. Blood Purif 2009; 28(3): 253-9.
  • 18. Henning BF, Zidek W, Linder B, Tepel M. Kidney Blood Press Res. Mean platelet volume and coronary heart disease in hemodialysis patients. Kidney Blood Press Res 2002; 25(2): 103-8.
  • 19. Papanas N, Symeonidis G, Maltezos E, et al. Mean platelet volume in patients with type 2 diabetes mellitus. Platelets 2004; 15(8): 475-8.
  • 20. Hekimsoy Z, Payzin B, Ornek T, Kandoğan G. Mean platelet volume in Type 2 diabetic patients. J Diabetes Complications 2004; 18(3): 173-6.
  • 21. Tavil Y, Sen N, Yazici H, Turfan M, Hizal F, Cengel A, Abaci A. Coronary heart disease is associated with mean platelet volume in type 2 diabetic patients. Platelets 2010; 21(5): 368-72.
  • 22. Muscari A, De Pascalis S, Cenni A, et al. Determinants of mean platelet volume (MPV) in an elderly population: relevance of body fat, blood glucose and ischaemic electrocardiographic changes. Thromb Haemost 2008; 99(6): 1079-84.
  • 23. Park Y, Schoene N, Harris W. Mean platelet volume as an indicator of platelet activation: methodological issues. Platelets 2002; 13: 301-6

The Effect of the Presence of Diabetes to Platelet Indices in Geriatric Hemodialysis Patients

Yıl 2012, Cilt: 1 Sayı: 2, 42 - 45, 01.10.2012

Öz

This study was aimed at evaluating platelet indices in diabetic versus non-diabetic geriatric hemodialysis patients. This study included 42 geriatric hemodialysis patients with DM 20 men, 22 women; mean age 71,2±5,5 and 55 non-DM 30 men, 25 women; mean age 72,1±4,6 from the hospital. Anticoagulated blood was collected and analyzed in an automated blood cell counter for platelet count and indices [Mean platelet volume MPV , platelet distribution width PDW ]. MPV and PDW were significantly higher in diabetic patients compared to the non-diabetics P

Kaynakça

  • 1. Chu SG, Becker RC, Berger PB, Bhatt DL, Eikelboom JW, Konkle B, Mohler ER, Reilly MP, Berger JS. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and metaanalysis. J Thromb Haemost 2010; 8: 148–56.
  • 2. Sandhaus LM, Meyer P. How useful are CBC and reticulocyte reports to clinicians? Am J Clin Pathol 2002;118(5): 787-93.
  • 3. Bath PM, Butterworth RJ. Platelet size: measurement, physiology and vascular disease. Blood Coagul Fibrinolysis 1996; 7(2): 157-61.
  • 4. Martin TJ, Smith IL, Nolan RD, Dusting GJ. Prostanoids in platelet-vascular interactions. Am J Cardiol 1983; 52(2): 22A-27A.
  • 5. Kishk YT, Trowbridge EA, Martin JF. Platelet volume subpopulations in acute myocardial infarction: an investigation of their homogeneity for smoking, infarct size and site. Clin Sci (Lond) 1985; 68(4): 419-25.
  • 6. Tohgi H, Suzuki H, Tamura K, Kimura B. Platelet volume, aggregation, and adenosine triphosphate release in cerebral thrombosis. Stroke 1991; 22(1): 17-21.
  • 7. Sharpe PC, Trinick T. Mean platelet volume in diabetes mellitus. Q J Med 1993; 86(11): 739-42.
  • 8. Endler G, Klimesch A, Sunder-Plassmann H, et al. Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease. Br J Haematol 2002; 117(2): 399- 404.
  • 9. Jindal S, Gupta S, Gupta R, et al. Platelet indices in diabetes mellitus: indicators of diabetic microvascular complications. Hematology 2011; 16(2): 86-9.
  • 10. American Diabetes Association. Standards of medical care in diabetes-2010. Diab Care 2010; 33(Suppl 1): 11–61.
  • 11. US Renal Data System. USRDS 1994 Annual Data Report. Bethesda, Md: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 1994.
  • 12. McMillan MA, Briggs JD, Junor BJ. Outcome of renal replacement treatment in patients with diabetes mellitus. BMJ 1990; 301: 540 –4.
  • 13. Hirschl MM, Heinz G, Sunder-Plassmann G, Derfler K. Renal replacement therapy in type 2 diabetic patients: 10 years’ experience. Am J Kidney Dis 1992; 20: 564 –8.
  • 14. Rischen-Vos J, van der Woude FJ, Tegzess AM, et al. Increased morbidity and mortality in patients with diabetes mellitus after kidney transplantation as compared with non-diabetic patients. Nephrol Dial Transplant 1992; 7: 433–7.
  • 15. USRDS 2007 Annual Data Report: Atlas of Chronic Kidney Disease And End-Stage Renal Disease in the United States. Volume II Reference Tables. Bethesda, MD: National Kidney and Urologic Diseases Information Clearinghouse, 2007.
  • 16. USRDS 2007 Annual Data Report: Atlas of Chronic Kidney Disease And End-Stage Renal Disease in the United States. Volume 1. Bethesda, MD: National Kidney and Urologic Diseases Information Clearinghouse, 2007.
  • 17. Gritters-van den Oever M, Schoorl M, Schoorl M, Bartels PC, Grooteman MP, Nubé MJ. The role of the extracorporeal circuit in the trapping and degranulation of platelets. Blood Purif 2009; 28(3): 253-9.
  • 18. Henning BF, Zidek W, Linder B, Tepel M. Kidney Blood Press Res. Mean platelet volume and coronary heart disease in hemodialysis patients. Kidney Blood Press Res 2002; 25(2): 103-8.
  • 19. Papanas N, Symeonidis G, Maltezos E, et al. Mean platelet volume in patients with type 2 diabetes mellitus. Platelets 2004; 15(8): 475-8.
  • 20. Hekimsoy Z, Payzin B, Ornek T, Kandoğan G. Mean platelet volume in Type 2 diabetic patients. J Diabetes Complications 2004; 18(3): 173-6.
  • 21. Tavil Y, Sen N, Yazici H, Turfan M, Hizal F, Cengel A, Abaci A. Coronary heart disease is associated with mean platelet volume in type 2 diabetic patients. Platelets 2010; 21(5): 368-72.
  • 22. Muscari A, De Pascalis S, Cenni A, et al. Determinants of mean platelet volume (MPV) in an elderly population: relevance of body fat, blood glucose and ischaemic electrocardiographic changes. Thromb Haemost 2008; 99(6): 1079-84.
  • 23. Park Y, Schoene N, Harris W. Mean platelet volume as an indicator of platelet activation: methodological issues. Platelets 2002; 13: 301-6
Toplam 23 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makalesi
Yazarlar

Recep Bentli Bu kişi benim

Süleyman Köz Bu kişi benim

Abdulvahap Coşkun Bu kişi benim

İdris Şahin Bu kişi benim

Yayımlanma Tarihi 1 Ekim 2012
Yayımlandığı Sayı Yıl 2012 Cilt: 1 Sayı: 2

Kaynak Göster

APA Bentli, R., Köz, S., Coşkun, A., Şahin, İ. (2012). Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi. Annals of Health Sciences Research, 1(2), 42-45.
AMA Bentli R, Köz S, Coşkun A, Şahin İ. Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi. Ann Health Sci Res. Ekim 2012;1(2):42-45.
Chicago Bentli, Recep, Süleyman Köz, Abdulvahap Coşkun, ve İdris Şahin. “Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi”. Annals of Health Sciences Research 1, sy. 2 (Ekim 2012): 42-45.
EndNote Bentli R, Köz S, Coşkun A, Şahin İ (01 Ekim 2012) Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi. Annals of Health Sciences Research 1 2 42–45.
IEEE R. Bentli, S. Köz, A. Coşkun, ve İ. Şahin, “Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi”, Ann Health Sci Res, c. 1, sy. 2, ss. 42–45, 2012.
ISNAD Bentli, Recep vd. “Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi”. Annals of Health Sciences Research 1/2 (Ekim 2012), 42-45.
JAMA Bentli R, Köz S, Coşkun A, Şahin İ. Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi. Ann Health Sci Res. 2012;1:42–45.
MLA Bentli, Recep vd. “Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi”. Annals of Health Sciences Research, c. 1, sy. 2, 2012, ss. 42-45.
Vancouver Bentli R, Köz S, Coşkun A, Şahin İ. Geriatrik Hemodiyaliz Hastalarında Diyabet Varlığının Trombosit İndekslerine Etkisi. Ann Health Sci Res. 2012;1(2):42-5.