Genetik bilimi ve kimlik

Yıl 2007, Sayı: 22, 75 - 102, 01.04.2007

Ömer Gökçümen

Öz

Biyoloji ve kimlik arasındaki ilişkiyle ilgili akademik çalışmalar uzun zamandır süregelmektedir. Özellikle ırksal kategoriler, hem akademik çevrelerde, hem de akademi dışında insan gruplarının biyolojik çeşitliliğini anlamada önemli yer tutmuşlardır. Ancak, son yıllarda bilim dünyası kimlik kavramının sabit bir yapı olarak anlayan tutumunu terk etmiştir. Genetik bilgi de, bu çaba içerisinde sabit biyolojik kimliklerin geçerliliğinin çürütülmesinde önemli rol oynamıştır. Bu gelişmelere rağmen, akademi dışında, genelde populasyon genetiği çalışmalarının etnik gruplara özgü `genleri' araştırmakta olduğu düşünülmektedir. Bazı etnik gruplar genetik araştırmaları coğrafi köklerini, etnik kökenlerini ve hatta grup kimliklerini `bilimsel' olarak meşrulaştırmak için kullanmaktadırlar (örn. Amerikan yerlileri, Lemba, Hindistanlı dokunulmazlar ve Afrika kökenli Amerikalılar). Bu çalışmalar gerçekten de bilimsel olarak değişik grupların tarihlerini anlamamıza ciddi katkılar sağlayacaktır. Ancak, etnik merkezli ve hatta ırkçı diskurs aynı verileri çarpıtarak kendi gruplarına avantaj sağlayacak şekilde çarpıtılabilir. Bu yüzden moleküler antropoloji çalışmalarının daha derin ve geniş olarak anlaşılmasını destekleyecek adımların atılması önemlidir. Bunun sonucunda oluşacak diyalog, genetik bilginin politik olarak yanlış kullanılmasını engellemekle kalmayacak, aynı zamanda insanlık tarihinin ve çeşitliliğin anlaşılmasına önemli katkılarda bulunacaktır

Anahtar Kelimeler

Genetik, Kimlik, Irk, Bioetik, Moleküler Antropoloji

GENETICS AND IDENTITY

Öz

The relationship between biology and identity is not a new area of academic inquiry. Racial categories, in particular, have set the framework for understanding human diversity both inside and outside of academia. In recent years, however, Western academics have taken an important role in the deconstruction of identity as a stable object of analysis. Contributing to this effort, genetic data have been utilized to problematize the notion of stable biological identities. Nevertheless, non-academic discourse has sometimes reproduced arguments, based on new genetic developments, which challenge the reflexive anti -essentialist identity that is produced in contemporary academia. For instance, population genetic studies are generally thought to show that certain `genes' are confined to particular ethnic groups. Indeed, several populations from different cultural backgrounds have already utilized genetic techniques to legitimize their origins, ethnicity and even group identity (e.g., indigenous American groups, Lemba, Indian `Untouchables', African Americans). While such studies will broaden our understanding of different population histories, ethnocentric or racist discourse can also represent these genetic data in a distorted way so as to support the claims of particular groups. For this reason, it will be important to promote a more comprehensive and deeper understanding of molecular genetic studies. The resulting dialogue will not only prevent the potential political misuse of genetic data, but also contribute significantly to our understanding of human history and diversity

Anahtar Kelimeler

Genetics, Identity, Race, Bioethics, Molecular Anthropology

Kaynakça

• Al-Azm, JS. 1981 Orientalism and Orientalism in Reverse. Orientalism: A Reader. Ed. A. L. Macfie. Edinburgh UP, 2000. 217-238. Edinburgh
• Althusser, Louis. 1971. Ideology and Ideological State Apparatuses. In: Lenin and Philosophy and Other Essays. Monthly Review Press. New York.
• Azoulay, KG. 2003. Not an Innocent Pursuit: The Politics of a ‘Jewish’ Genetic Signature’. Developing World Bioethics. 3/2:1471
• Bamshad M, Kivisild T, Watkins WS, Dixon ME, Ricker CE, Rao BB, et al. 2001. Genetic evidence on the origins of Indian caste populations. Genome Res. 11: 994-1004
• Barbujani G.et al. 1997 DNA variation and language affinities. American Journal of Human Genetics 61:1011-1014.
• Beaune, C. 1991. The Birth of an Ideology. University of California Press, Berkeley?
• Brodwin, P. 2002. Genetics, Identity, and the Anthropology of Essentialism. Anthropological Quarterly, 75 (2): pp. 323-330.
• Burchard, E.G., et al. 2003. The Importance of Race and Ethnic Background in Biomedical Research and Clinical Practice. New England Journal of Medicine, 348(12):1170-1175
• Butler, R. 1985. Foreword. In: Nicholas Goodrick-Clarke, N. The Occult roots of Nazism. NYU Press. NY
• Cavalli-Sforza, L.L. 2000. Genes, People and Languages. North Point Press. NY.
• Derrida, J. 1978. Writing and Difference. University of Chicago Pres. Chicago
• Dhruvarajan, V., and J. Vickers. 2002, Gender, Race and Nation. University of Toronto Press, Toronto.
• Dula A, C. Royal, M.G. Secundy. 2003. The ethical and social implications of exploring African American genealogies. Developing World Bioethics. 3(2):133-41.
• Eliot, C. and Brodwin P. 2002. Identity and genetic ancestry tracing. British Medical Journal. 325(7378):1469-71.
• Foucault, M. 1990. The History of Sexuality. Vintage Books. NY.
• Foster EA, Jobling MA, Taylor PG, Donnelly P, de Knjff P, Mieremet R, Zerjal T and Tyler-Smith C. 1998. Jefferson fathered slave’s last child. 396(6706):27-8
• Genetics and Identity Project website http://www.bioethics.umn.edu/genetics_and_identity/index.html
• Giddens, A. 1991. Modernity and Self-identity. Polity Press: Oxford.
• Glaberson, W. 2001. Who is a Seminole and who gets to decide? New York Times Jan 29-A1
• Hall, S. and P. du Gay (eds). 1996. Questions of Cultural Identity. Sage Publications: London.
• Hammer MF, Redd AJ, Wood ET, Bonner MR, Jarjanazi H, Karafet T, Santachiara- Benerecetti S, Oppenheim A, Jobling MA, Jenkins T, Ostrer H, Bonne-Tamir B. 1997. Y Chromosome of Jewish Priests. Nature. 385:32.
• Herodotus. 1996. The Histories, (trs) Aubrey De Sélincourt. Penguin Books, NY.
• Jones, J.F., C.K. Ritenbaugh, M.A. Spence, A. Hayward. 1991. Severe combined immunodeficiency among the Navajo. Characterization of phenotypes, epidemiology, and population genetics. Human Biology 63(5):669-82
• Kaestle, F.A., and D.G. Smith. 2001. Ancient native American DNA from western Nevada: Implications for the Numic expansion hypothesis. American Journal of Physical Anthropology 115:1-12.
• Kaiwar, V., and S. Mazumdar. 2003. Antimonies of Modernity. Duke University Press: Durham.
• Kevles, D.J. and L. Hodd (eds). 1992. The Code of Codes: Scientific and Social Issues in the Human Genome Project. Harvard University Press, Cambridge.
• Kleiman, Y. 2001. The Cohanim/DNA Connection: The Fascinating Story of How DNA Studies Confirm an Ancient Biblical Tradition. aish.com. Aish HaTorah. 28 Feb. (http://aish.com/societywork/sciencenature/The_Cohanim_- _DNA_Connection.asp.)
• Kurlansky, M. 1999. The Basque History of the World. Walker and co. NewYork.
• Larson, B. 2004. Trials of Nation Making: Liberalism, race and ethnicity in the Andes, 1810-1910. Cambridge University Press, Cambridge.
• Marshall, E. 1998. DNA Studies challenge the meaning of Race. Science 282:654- 655.
• Mosse, G. 1984. Towards the Final Solution: A History of European Racism. University of Wisconsin Press: Madison.
• Nokwisa Yona, "DNA testing in Vermont," The Abolitionist Examiner, Apr./May, 2001, http://www.multiracial.com/abolitionist/word/yona-parttwo.html.
• Olson, S. 2003. Mapping Human History: Genes, Race, and Our Common Origins. Mariner Books, Boston.
• Preucel, B., and I. Hodder. 1996. Contemporary Archaeology Theory. Blackwell Publishers Ltd., Malden, MA
• Price, R.A., M.A. Charles, D.J. Pettitt, W.C. Knowler. 1994. Obesity in Pima Indians: genetic segregation analyses of body mass index complicated by temporal increases in obesity. Human Biology 66(2):251-74.
• Price, R.A., K. Lunetta, R. Ness, M.A. Charles, M.F. Saad, E. Ravussin, P.H. Bennett, D.J. Pettitt, W.C. Knowler. 1992. Obesity in Pima Indians. Distribution characteristics and possible thresholds for genetic studies. Int J Obes Relat Metab Disord 16(11):851-7.
• Renfrew, C., and K. Boyle (eds). 2000. Archaeogenetics: DNA and the Population Prehistory of Europe. McDonald Institute Press. Cambridge.
• Ridley M. 2000. Genome. New York: Harper Collins.
• Rotimi CN. 2003. Genetic ancestry tracing and the African identity. A double edged sword. Developing World Bioethics 3/2: 156.
• Satel, S. 2001. Medicine’s Race Problem. Policy Review, December/110. (http://www.policyreview.org/DEC01/satel.html)
• Tallbear, K. 2000. Genetics, culture and identity in Indian Country. Paper presented at the 7th International Congress of Ethnobiology. Athens, GA, Oct 23-27, 2000?
• Tallbear, K. 2002. DNA, blood and racializing the tribe. Wicazo SA Review 17: 2- 19.
• Tallbear, K. 2003. TallBear: Can DNA determine who is American Indian? Indian County Today. December 03. (http://www.indiancountry.com/index.php?1070457107).
• Thomas, M., T. Parfitt, D.A. Weiss, K. Skorecki, J.F. Wilson, M. Roux, N. Bradman, D.B. Goldstin. 2000. Y-Chromosomes traveling south: The Cohen modal haplotype and the origins of Lemba – “The Black Jews of Southern Africa.” Am J Hum Genet 66(2): 674-86.
• Torroni A, Schurr TG, Cabell MF, Brown MD, Neel JV, Larsen M, Smith DG, Vullo C, Wallace DC. 1993. Asian affinities and continental radiation of the four founding Native American mitochondrial DNAs. Am. J. Hum. Genet. 53(3): 563-590.
• Wade, N. 2001. For genome mappers, the tricky terrain of race requires some careful navigation. New York Times, July 20.
• Walston J, Silver K, Bogardus C, Knowler WC, Celi FS, Austin S, Manning B, Strosberg AD, Stern MP, Raben N. 1995. Time of onset of non-insulin- dependent diabetes mellitus and genetic variation in the beta 3-adrenergic- receptor gene. N Engl J Med 333(6): 343-7.
• Weitz E. 2003. A Century of Genocide: Utopias of Race and Nation. Princeton: Princeton University Press.
• Wilson JF, Weiss DA, Richards M, Thomas MG, Bradman N, Goldstein DB. 2001 Genetic evidence for different male and female roles during cultural transitions in the British Isles. Proc Natl Acad Sci USA. 98(9): 5078-83
• Wolpe PR. 2002. Bioethics, the Genome and the Jewish Body. In: Conservative Judaism. 54(3):14-25.
• Zoloth, L. 2003 Yearning for the long lost home: The Lemba and the Jewish narrative of genetic return. Developing World Bioethics 3/2: 1471.