The effect of decortication on spinal fusion: an in vivo study in guinea pigs

Cilt: 35 Sayı: 2 11 Eylül 2006
  • Nikola Azar
  • Cuneyt Mirzanli
  • Erol Bozkurt
  • Bunyamin Berber
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The effect of decortication on spinal fusion: an in vivo study in guinea pigs

Abstract

Objectives: Although spinal fusion is one of the most commonly used procedures in spinal surgery its properties are not fully known. The role of decortication is still not clear. In this animal model, we investigated the effect of decortication on spinal fusion. Methods: The study included 30 male guinea pigs (Cavia porcellus). Spine exposure was obtained through the right subperiosteal dissection between L2 and L6 in all animals, whereas the left sides were used as controls. The animals were assigned to three groups including decortication and autografting (group 1), decortication, instrumentation, and autografting (group 2), and instrumentation and autografting without decortication (group 3). All animals were sacrificed in the sixth postoperative week. The fusion mass was assessed by means of macroscopic evaluation, manual stress test, radiologic examination, and microscopic evaluation. Results: Based on segmentary evaluations, fusion was obtained in 80%, 95%, and 92.5% in groups 1, 2, and 3, respectively. The results were found statistically significant (Kruskal-Wallis nonparametric ANOVA test, p<0.001). Conclusion: The results show that decortication should be an essential step for spinal fusion if spinal instrumentation is not considered. However, in case of a stable instrumentation, decortication seems to exert no positive effect on the formation of spinal fusion.

Keywords

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Nikola Azar Bu kişi benim

Cuneyt Mirzanli Bu kişi benim

Erol Bozkurt Bu kişi benim

Bunyamin Berber Bu kişi benim

Yayımlanma Tarihi

11 Eylül 2006

Gönderilme Tarihi

6 Mart 2014

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2001 Cilt: 35 Sayı: 2

Kaynak Göster

APA
Azar, N., Mirzanli, C., Bozkurt, E., & Berber, B. (2006). The effect of decortication on spinal fusion: an in vivo study in guinea pigs. Acta Orthopaedica et Traumatologica Turcica, 35(2), 163-168. https://doi.org/10.3944/aott.v35i2.1717
AMA
1.Azar N, Mirzanli C, Bozkurt E, Berber B. The effect of decortication on spinal fusion: an in vivo study in guinea pigs. Acta Orthopaedica et Traumatologica Turcica. 2006;35(2):163-168. doi:10.3944/aott.v35i2.1717
Chicago
Azar, Nikola, Cuneyt Mirzanli, Erol Bozkurt, ve Bunyamin Berber. 2006. “The effect of decortication on spinal fusion: an in vivo study in guinea pigs”. Acta Orthopaedica et Traumatologica Turcica 35 (2): 163-68. https://doi.org/10.3944/aott.v35i2.1717.
EndNote
Azar N, Mirzanli C, Bozkurt E, Berber B (01 Eylül 2006) The effect of decortication on spinal fusion: an in vivo study in guinea pigs. Acta Orthopaedica et Traumatologica Turcica 35 2 163–168.
IEEE
[1]N. Azar, C. Mirzanli, E. Bozkurt, ve B. Berber, “The effect of decortication on spinal fusion: an in vivo study in guinea pigs”, Acta Orthopaedica et Traumatologica Turcica, c. 35, sy 2, ss. 163–168, Eyl. 2006, doi: 10.3944/aott.v35i2.1717.
ISNAD
Azar, Nikola - Mirzanli, Cuneyt - Bozkurt, Erol - Berber, Bunyamin. “The effect of decortication on spinal fusion: an in vivo study in guinea pigs”. Acta Orthopaedica et Traumatologica Turcica 35/2 (01 Eylül 2006): 163-168. https://doi.org/10.3944/aott.v35i2.1717.
JAMA
1.Azar N, Mirzanli C, Bozkurt E, Berber B. The effect of decortication on spinal fusion: an in vivo study in guinea pigs. Acta Orthopaedica et Traumatologica Turcica. 2006;35:163–168.
MLA
Azar, Nikola, vd. “The effect of decortication on spinal fusion: an in vivo study in guinea pigs”. Acta Orthopaedica et Traumatologica Turcica, c. 35, sy 2, Eylül 2006, ss. 163-8, doi:10.3944/aott.v35i2.1717.
Vancouver
1.Nikola Azar, Cuneyt Mirzanli, Erol Bozkurt, Bunyamin Berber. The effect of decortication on spinal fusion: an in vivo study in guinea pigs. Acta Orthopaedica et Traumatologica Turcica. 01 Eylül 2006;35(2):163-8. doi:10.3944/aott.v35i2.1717