The effects of surgical margins on local control and survival in extremity soft tissue sarcomas

Cilt: 37 Sayı: 5 11 Eylül 2006
  • Cemil Yildiz
  • Kaan Erler
  • Serkan Bilgic
  • A. Atesalp
  • Mustafa Basbozkurt
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The effects of surgical margins on local control and survival in extremity soft tissue sarcomas

Öz

Objectives: We evaluated the effects of surgical margins and other prognostic factors on local control and survival in extremity soft tissue sarcomas. Methods: The study included 40 patients (34 males, 6 females; mean age 45 years; range 13 to 77 years) who underwent treatment for extremity soft tissue sarcomas. Of these, 14 patients presented with recurrences following treatment elsewhere. Preoperatively, nine patients and eight patients; postoperatively, 35 patients and 25 patients received radiotherapy and chemotherapy, respectively. Limb-salvaging surgery was performed in 35 patients (87.5%), of whom 28 patients (70%) received an extended resection, and seven patients received a marginal resection. Five patients (12.5%) required amputation. Negative surgical margins were achieved in 34 patients (85%), while six patients (15%) had positive surgical margins. The mean follow-up period was 58 months (range 13 to 124 months). Results: Five patients (12.5%) developed local recurrences following marginal resection (n=4), and amputation. No local recurrences were seen in patients receiving an extended resection or in those having negative surgical margins. Five-year survival rates were 51% and 49% in patients whose initial diagnoses were made in our department and elsewhere, respectively. Significant correlations were found between extended resection (p=0.0001) and negative surgical margins (p=0.0001) and local control; and between tumor grade and survival (p=0.002). Positive surgical margins and local recurrences did not decrease survival. Conclusion: Achievement of negative surgical margins promotes local control in extremity soft tissue sarcomas. A careful preoperative planning and utilization of neoadjuvant therapies highly increase the possibility of negative surgical margins.

Anahtar Kelimeler

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Cemil Yildiz Bu kişi benim

Kaan Erler Bu kişi benim

Serkan Bilgic Bu kişi benim

A. Atesalp Bu kişi benim

Mustafa Basbozkurt Bu kişi benim

Yayımlanma Tarihi

11 Eylül 2006

Gönderilme Tarihi

6 Mart 2014

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2003 Cilt: 37 Sayı: 5

Kaynak Göster

APA
Yildiz, C., Erler, K., Bilgic, S., Atesalp, A., & Basbozkurt, M. (2006). The effects of surgical margins on local control and survival in extremity soft tissue sarcomas. Acta Orthopaedica et Traumatologica Turcica, 37(5), 359-367. https://doi.org/10.3944/aott.v37i5.800
AMA
1.Yildiz C, Erler K, Bilgic S, Atesalp A, Basbozkurt M. The effects of surgical margins on local control and survival in extremity soft tissue sarcomas. Acta Orthopaedica et Traumatologica Turcica. 2006;37(5):359-367. doi:10.3944/aott.v37i5.800
Chicago
Yildiz, Cemil, Kaan Erler, Serkan Bilgic, A. Atesalp, ve Mustafa Basbozkurt. 2006. “The effects of surgical margins on local control and survival in extremity soft tissue sarcomas”. Acta Orthopaedica et Traumatologica Turcica 37 (5): 359-67. https://doi.org/10.3944/aott.v37i5.800.
EndNote
Yildiz C, Erler K, Bilgic S, Atesalp A, Basbozkurt M (01 Eylül 2006) The effects of surgical margins on local control and survival in extremity soft tissue sarcomas. Acta Orthopaedica et Traumatologica Turcica 37 5 359–367.
IEEE
[1]C. Yildiz, K. Erler, S. Bilgic, A. Atesalp, ve M. Basbozkurt, “The effects of surgical margins on local control and survival in extremity soft tissue sarcomas”, Acta Orthopaedica et Traumatologica Turcica, c. 37, sy 5, ss. 359–367, Eyl. 2006, doi: 10.3944/aott.v37i5.800.
ISNAD
Yildiz, Cemil - Erler, Kaan - Bilgic, Serkan - Atesalp, A. - Basbozkurt, Mustafa. “The effects of surgical margins on local control and survival in extremity soft tissue sarcomas”. Acta Orthopaedica et Traumatologica Turcica 37/5 (01 Eylül 2006): 359-367. https://doi.org/10.3944/aott.v37i5.800.
JAMA
1.Yildiz C, Erler K, Bilgic S, Atesalp A, Basbozkurt M. The effects of surgical margins on local control and survival in extremity soft tissue sarcomas. Acta Orthopaedica et Traumatologica Turcica. 2006;37:359–367.
MLA
Yildiz, Cemil, vd. “The effects of surgical margins on local control and survival in extremity soft tissue sarcomas”. Acta Orthopaedica et Traumatologica Turcica, c. 37, sy 5, Eylül 2006, ss. 359-67, doi:10.3944/aott.v37i5.800.
Vancouver
1.Cemil Yildiz, Kaan Erler, Serkan Bilgic, A. Atesalp, Mustafa Basbozkurt. The effects of surgical margins on local control and survival in extremity soft tissue sarcomas. Acta Orthopaedica et Traumatologica Turcica. 01 Eylül 2006;37(5):359-67. doi:10.3944/aott.v37i5.800