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Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları

Yıl 2024, Cilt: 4 Sayı: 2, 68 - 82, 23.11.2024
https://doi.org/10.62425/atakim.1459951

Öz

Kozmetikler, antik çağlardan beri kişisel bakım için kullanılan ürünlerdir. Dünya çapında büyük bir pazar payına sahip ve milyonlarca kişi tarafından düzenli olarak tüketilmektedir. Kozmetik ürünlere olan talebin her geçen gün artması ve teknolojik gelişmelerle birlikte nano ölçekli materyaller içeren nanokozmetikler olarak adlandırılan yeni formülasyonlar ortaya çıkmıştır. Nanokozmetiklerde; nanopartiküller, nanoemülsiyonlar, lipozomlar, niozomlar, mikroemülsiyonlar, katı lipit nanopartikülleri, nanoyapılı lipit taşıyıcılar ve nanoküreler gibi çok sayıda nanotaşıyıcı kullanılmaktadır. Kullanılan nanotaşıyıcıların her biri benzersiz fiziksel, kimyasal ve biyolojik özelliklere sahiptir. Bu özellikler, antioksidan, yaşlanma karşıtı ve daha fazlasını kapsayan yeni kozmetik ürünlerin ortaya çıkmasına neden olmaktadır. Nanokozmetikler, geleneksel kozmetiklere göre aktif maddelerin cilde daha iyi nüfuz etmesi, transdermal kontrollü salınım olasılığı, kararsız aktif maddelerin bozulmasına karşı koruma, formülasyonun daha iyi stabilizasyonu ve düşük toksisite gibi avantajlar sunar. Özellikle yeşil sentez metotları kullanılarak metal/metal oksit nanopartiküllerin sentezi ve nanokozmetiklerde kullanımı, kozmetik sektöründe yenilikçi yaklaşımların ortaya çıkmasını sağlamıştır. Kozmetik sektöründe, güneş koruyucu teknolojisi, özellikle ZnO nanopartiküllerinin kullanımıyla önemli ölçüde geliştirilmiştir. Güneş koruyucu ürünlerde ZnO nanopartiküllerinin etkinliğini arttırmaya yönelik araştırmalar, nanoformülasyonların optimizasyonuna odaklanmıştır. ZnO NP’lerinin cilt ile etkileşimi üzerine yapılan çalışmalar, ürünlerin biyouyumluluğunun ve toksisitesinin değerlendirilmesinde önemli bir rol oynamaktadır. Bu derleme makalesinde nanoteknoloji ile kozmetik endüstrisinin kesişimi ayrıntılı olarak incelenerek, nano ölçekli kozmetik ürünler, ZnO NP’lerinin kozmetik ve güneş koruyucu formülasyonlarındaki uygulamaları genel yaklaşımlarla sunulmaktadır.

Kaynakça

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The Role of ZnO Nanoparticles in Sunscreen Products: Innovative Dimensions of Sunscreen Technology

Yıl 2024, Cilt: 4 Sayı: 2, 68 - 82, 23.11.2024
https://doi.org/10.62425/atakim.1459951

Öz

Cosmetics are products used for personal care since ancient times. They have a large market share worldwide and are consumed regularly by millions of people. With the increasing demand for cosmetic products and technological developments, new formulations called nanocosmetics containing nanoscale materials have emerged. Numerous nanocarriers such as nanoparticles, nanoemulsions, liposomes, niosomes, microemulsions, solid lipid nanoparticles, nanostructured lipid carriers and nanospheres are used in nanocosmetics. Each of the nanocarriers used has unique physical, chemical and biological properties. These properties lead to the emergence of new cosmetic products that include antioxidants, anti-aging and more. Nanocosmetics offer advantages such as better penetration of active ingredients into the skin, the possibility of transdermal controlled release, protection against degradation of unstable active ingredients, better stabilization of the formulation and low toxicity compared to traditional cosmetics. Especially the synthesis of metal/metal oxide nanoparticles using green synthesis methods and their use in nanocosmetics have provided innovative approaches in the cosmetics sector. In the cosmetics sector, sunscreen technology has been significantly improved, especially with the use of ZnO nanoparticles. Research to increase the effectiveness of ZnO nanoparticles in sunscreen products has focused on the optimization of nanoformulations. Studies on the interaction of ZnO NPs with the skin play an important role in the evaluation of biocompatibility and toxicity of the products. In this review article, the intersection of nanotechnology and the cosmetics industry is examined in detail, and nanoscale cosmetic products, applications of ZnO NPs in cosmetics and sunscreen formulations are presented with general approaches.

Kaynakça

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  • 2. Mobasser S, Firoozi AA. Review of nanotechnology applications in science and engineering. J Civil Eng Urban. 2016;6(4):84-93.
  • 3. Katz LM, Dewan K, Bronaugh RL. Nanotechnology in cosmetics. Food Chem Toxicol. 2015;85:127-137.
  • 4. Arya K, Bhar R, Kataria R, Mehta SK. Nanomaterials in the cosmetics industry: A greener approach. Green Nanomaterials for Industrial Applications. Elsevier; 2022:207-253.
  • 5. Mihranyan A, Ferraz N, Strømme M. Current status and future prospects of nanotechnology in cosmetics. Prog Mater Sci. 2012;57(5):875-910.
  • 6. Liu Y, Zhao J, Chen J, Miao X. Nanocrystals in cosmetics and cosmeceuticals by topical delivery. Colloids SurF B: Biointerfaces. 2023:113385.
  • 7. Pandey A, Jatana GK, Sonthalia S. Cosmeceuticals. Treasure island (FL). StatPearls Publishing:2019.
  • 8. Cardoza C, Nagtode V, Pratap A, Mali SN. Emerging applications of nanotechnology in cosmeceutical health science: Latest updates. Health Sci Rev. 2022:4:100051.
  • 9. Khezri K, Saeedi M, Dizaj SM. Application of nanoparticles in percutaneous delivery of active ingredients in cosmetic preparations. Biomed Pharmacother. 2018;106:1499-1505.
  • 10. Chiari-Andréo BG, de Almeida-Cincotto MGJ, Oshiro Jr JA, Taniguchi CYY, Chiavacci LA, Isaac VLB. Nanoparticles for cosmetic use and its application. Nanopart Pharmacother. Elsevier; 2019:113-146.
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  • 12. Bruna T, Maldonado-Bravo F, Jara P, Caro N. Silver nanoparticles and their antibacterial applications. Int J Mol Sci. 2021;22(13):7202.
  • 13. Raj S, Jose S, Sumod U, Sabitha M. Nanotechnology in cosmetics: Opportunities and challenges. J. Pharm Bioallied Sci. 2012;4(3):186.
  • 14. Banik B, Borkotoky S, Das MK. Biosynthesized colloidal metallic nanoparticles-based nanocosmetic formulations. Nanocosmeceuticals. 2022:369-388.
  • 15. Pal A, Alam S, Mittal S, et al. UVB irradiation-enhanced zinc oxide nanoparticles-induced DNA damage and cell death in mouse skin. Mutat Res Genet Toxicol Environ Mutagen. 2016;807:15-24.
  • 16. Zou W, Ramanathan R, Urban S, et al. Sunscreen testing: A critical perspective and future roadmap. TrAC Trends Anal Chem. 2022;157:116724.
  • 17. He H, Li A, Li S, Tang J, Li L, Xiong L. Natural components in sunscreens: Topical formulations with sun protection factor (SPF). Biomed Pharmacother. 2020;134:111161
  • 18. Santos A, Marto J, Cha-Cha R, et al. Nanotechnology-based sunscreens—A review. Mater Today Chem. 2022;23:100709.
  • 19. Ahmady A, Amini MH, Zhakfar AM, Babak G, Sediqi MN. Sun protective potential and physical stability of herbal sunscreen developed from afghan medicinal plants. Turk J Pharm Sci. 2020;17(3):285.
  • 20. Sarkany R. Sun protection. Medicine. 2021;49(7):453-456.
  • 21. Bocca B, Caimi S, Senofonte O, Alimonti A, Petrucci F. ICP-MS based methods to characterize nanoparticles of TiO2 and ZnO in sunscreens with focus on regulatory and safety issues. Sci Total Environ. 2018;630:922-930.
  • 22. Breunig HG, Weinigel M, König K. In vivo imaging of ZnO nanoparticles from sunscreen on human skin with a mobile multiphoton tomograph. BioNanoScience. 2015;5:42-47.
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  • 24. Yousefi F, Mousavi SB, Heris SZ, Naghash-Hamed S. UV-shielding properties of a cost-effective hybrid PMMA-based thin film coatings using TiO2 and ZnO nanoparticles: a comprehensive evaluation. Scient Reports. 2023;13(1):7116.
  • 25. Mascarenhas-Melo F, Mathur A, Murugappan S, et al. Inorganic nanoparticles in dermopharmaceutical and cosmetic products: properties, formulation development, toxicity, and regulatory issues. Eur J Pharm Biopharm. 2023;192:25-40.
  • 26. Tiwari N, Kumar D, Priyadarshani A, et al. Recent progress in polymeric biomaterials and their potential applications in skin regeneration and wound care management. J Drug Deliv Sci Tech. 2023:82:104319.
  • 27. Niska K, Zielinska E, Radomski MW, Inkielewicz-Stepniak I. Metal nanoparticles in dermatology and cosmetology: Interactions with human skin cells. Chem Biol Interact. 2018;295:38-51.
  • 28. Abou-Dahech M, Boddu SH, Bachu RD, et al. A mini-review on limitations associated with UV filters. Arab J Chem. 2022;15(11):104212.
  • 29. Nagar V, Singh T, Tiwari Y, et al. ZnO Nanoparticles: Exposure, toxicity mechanism and assessment. Mater Today Proc. 2022;69:56-63.
  • 30. Reinosa JJ, Docio CMÁ, Ramírez VZ, Lozano JFF. Hierarchical nano ZnO-micro TiO2 composites: High UV protection yield lowering photodegradation in sunscreens. Ceram Int. 2018;44(3):2827-2834.
  • 31. Rabani I, Lee S-H, Kim H-S, et al. Engineering-safer-by design ZnO nanoparticles incorporated cellulose nanofiber hybrid for high UV protection and low photocatalytic activity with mechanism. J Environ Chem Eng. 2021;9(5):105845.
  • 32. Ma H, Williams PL, Diamond SA. Ecotoxicity of manufactured ZnO nanoparticles–a review. Environ Pollut. 2013;172:76-85.
  • 33. Uribe-López M, Hidalgo-López M, López-González R, et al. Photocatalytic activity of ZnO nanoparticles and the role of the synthesis method on their physical and chemical properties. J Photochem Photobiol A Chem. 2021;404:112866.
  • 34. Sharma R, Garg R, Kumari A. A review on biogenic synthesis, applications and toxicity aspects of zinc oxide nanoparticles. EXCLI journal. 2020;19:1325.
  • 35. Haque MJ, Bellah MM, Hassan MR, Rahman S. Synthesis of ZnO nanoparticles by two different methods & comparison of their structural, antibacterial, photocatalytic and optical properties. Nano Express. 2020;1(1):010007.
  • 36. Awan F, Islam MS, Ma Y, et al. Cellulose nanocrystal–ZnO nanohybrids for controlling photocatalytic activity and UV protection in cosmetic formulation. ACS Omega. 2018;3(10):12403-12411.
  • 37. Sharma RR, Deep A, Abdullah ST. Herbal products as skincare therapeutic agents against ultraviolet radiation-induced skin disorders. J Ayurveda Integr Med. 2022;13(1):100500.
  • 38. Gupta S, Bansal R, Gupta S, Jindal N, Jindal A. Nanocarriers and nanoparticles for skin care and dermatological treatments. Indian Dermatol Online J. 2013;4(4):267.
  • 39. Chauhan R, Kumar A, Tripathi R, Kumar A. Advancing of zinc oxide nanoparticles for cosmetic applications. Handbook of consumer Nanoproducts. Springer; 2022:1-16.
  • 40. Adawi HI, Newbold MA, Reed JM, et al. Nano-enabled personal care products: Current developments in consumer safety. NanoImpact. 2018;11:170-179.
  • 41. Soenen SJ, Rivera-Gil P, Montenegro J-M, Parak WJ, De Smedt SC, Braeckmans K. Cellular toxicity of inorganic nanoparticles: common aspects and guidelines for improved nanotoxicity evaluation. Nano today. 2011;6(5):446-465.
  • 42. Saikia T, Sahu BP, Das MK. Safety evaluation and assessment of nanocosmeceutical products. Nanocosmeceuticals. Elsevier; 2022:511-524.
  • 43. Çağlar AB, Saral S. Kozmetolojide Toksisite Sorunu. Turk J Dermatol. 2014;8(4):248-251
  • 44. Singha LR, Das MK. Nanosunscreens for cosmeceutical applications. Nanocosmeceuticals. Elsevier; 2022:347-368.
  • 45. Ryu HJ, Seo MY, Jung SK, et al. Zinc oxide nanoparticles: a 90-day repeated-dose dermal toxicity study in rats. Int J Nanomedicine. 2014;9(sup2):137-144.
  • 46. Subramaniam VD, Prasad SV, Banerjee A, et al. Health hazards of nanoparticles: understanding the toxicity mechanism of nanosized ZnO in cosmetic products. Drug Chem Toxicol. 2019;42(1):84-93.
  • 47. Muthuraman P, Ramkumar K, Kim DH. Analysis of dose-dependent effect of zinc oxide nanoparticles on the oxidative stress and antioxidant enzyme activity in adipocytes. Appl Biochem Biotechnol. 2014;174:2851-2863.
  • 48. Khan M, Naqvi AH, Ahmad M. Comparative study of the cytotoxic and genotoxic potentials of zinc oxide and titanium dioxide nanoparticles. Toxicol Rep. 2015;2:765-774.
  • 49. Khare P, Sonane M, Nagar Y, et al. Size dependent toxicity of zinc oxide nano-particles in soil nematode Caenorhabditis elegans. Nanotoxicology. 2015;9(4):423-432.
  • 50. Du J, Tang J, Xu S, et al. ZnO nanoparticles: recent advances in ecotoxicity and risk assessment. Drug Chem Toxicol. 2020;43(3):322-333.
  • 51. Bartczak D, Baradez M, Merson S, Goenaga-Infante H, Marshall D. Surface ligand dependent toxicity of zinc oxide nanoparticles in HepG2 cell model. IOP Publishing; 2013:429:012015.
  • 52. Hascicek c. Surface modification of polymeric nanoparticulate drug. J Fac Pharm Ankara. 38(2):137-154.
  • 53. Girigoswami K, Viswanathan M, Murugesan R, Girigoswami A. Studies on polymer-coated zinc oxide nanoparticles: UV-blocking efficacy and in vivo toxicity. Mater Sci Eng C. 2015;56:501-510.
  • 54. Ickrath P, Wagner M, Scherzad A, et al. Time-dependent toxic and genotoxic effects of zinc oxide nanoparticles after long-term and repetitive exposure to human mesenchymal stem cells. Int J Environ Res Public Health. 2017;14(12):1590.
  • 55. Morganti P. Use and potential of nanotechnology in cosmetic dermatology. Clin Cosmet Investig Dermatol. 2010:5-13.
  • 56. Mirzaei H, Darroudi M. Zinc oxide nanoparticles: Biological synthesis and biomedical applications. Ceram Int. 2017;43(1):907-914.
  • 57. Huang X, Wang X, Wang S, Yang J, Zhong L, Pan J. UV and dark-triggered repetitive release and encapsulation of benzophenone-3 from biocompatible ZnO nanoparticles potential for skin protection. Nanoscale. 2013;5(12):5596-5601.
  • 58. Włodarczyk R, Kwarciak-Kozłowska A. Nanoparticles from the cosmetics and medical industries in legal and environmental aspects. Sustainability. 2021;13(11):5805.
  • 59. Morganti P. Nanocosmetics: an introduction. Nanocosmetics. Elsevier; 2020:3-16.
  • 60. Zouboulis CC, Ganceviciene R, Liakou AI, Theodoridis A, Elewa R, Makrantonaki E. Aesthetic aspects of skin aging, prevention, and local treatment. Dermatol Clin. 2019;37(4):365-372.
  • 61. Shanbhag S, Nayak A, Narayan R, Nayak UY. Anti-aging and sunscreens: paradigm shift in cosmetics. Adv Pharm Bull. 2019;9(3):348.
  • 62. Lin C-H, Lin M-H, Chung Y-K, Alalaiwe A, Hung C-F, Fang J-Y. Exploring the potential of the nano-based sunscreens and antioxidants for preventing and treating skin photoaging. Chemosphere. 2023:140702.
  • 63. Sharma S, Chophi R, Kaur H, Singh R. Differentiation of Cosmetic Foundation Creams Using Attenuated Total Reflection Fourier‐Transform Infrared Spectroscopy: A Rapid and NonDestructive Approach in Trace Evidence Analysis. J Forensic Sci. 2020;65(3):751-761.
  • 64. Sonia S, Ruckmani K, Sivakumar M. Antimicrobial and antioxidant potentials of biosynthesized colloidal zinc oxide nanoparticles for a fortified cold cream formulation: a potent nanocosmeceutical application. Mater Sci Eng C. 2017;79:581-589.
  • 65. Aspinall SR, Parker JK, Khutoryanskiy VV. Oral care product formulations, properties and challenges. Colloids Surf B Biointerfaces. 2021;200:111567.
  • 66. Abedi M, Ghasemi Y, Nemati MM. Nanotechnology in toothpaste: Fundamentals, trends, and safety. Heliyon. 2024;
  • 67. Khan ST, Al-Khedhairy AA, Musarrat J. ZnO and TiO 2 nanoparticles as novel antimicrobial agents for oral hygiene: A review. J Nanoparticle Res. 2015;17:1-16.
  • 68. El Shahawi AM. Incorporation of zinc oxide nanoparticles and it’s antibacterial effect on toothpaste. Bull Natl Res Cent. 2023;47(1):2.
  • 69. Sarma A, Chakraborty T, Das MK. Nanocosmeceuticals: Current trends, market analysis, and future trends. Nanocosmeceuticals. Elsevier; 2022:525-558.
  • 70. Fernandes AR, Dario MF, Pinto CASdO, Kaneko TM, Baby AR, Velasco MVR. Stability evaluation of organic Lip Balm. Braz J Pharm Sci. 2013;49:293-299.
  • 71. Ahmad I, Ahmad A, Iftekhar S, Khalid S, Aftab A, Raza SA. Role of nanoparticle in cosmetics industries. Bio Synth Nanopart Appl. CRC Press; 2019:173-204.
  • 72. Poojary PV, Sarkar S, Poojary AA, et al. Novel anti‐dandruff shampoo incorporated with ketoconazole‐coated zinc oxide nanoparticles using green tea extract. J Cosm Derm. 2024; 23: 563-575.
  • 73. Pal TK, Mondal O. Prospect of nanotechnology in cosmetics: Benefit and risk assess‐ment. World J Pharm Res. 2014;3(2):1909-1919.
  • 74. Dubey SK, Dey A, Singhvi G, Pandey MM, Singh V, Kesharwani P. Emerging trends of nanotechnology in advanced cosmetics. Colloids Surf B Biointerfaces. 2022;214:112440.
  • 75. Yadwade R, Gharpure S, Ankamwar B. Nanotechnology in cosmetics pros and cons. Nano Express. 2021;2(2):022003.
  • 76. Dahiya R, Dubey S, Dahiya S. Current global regulations for nanocosmeceuticals. Nanocosmeceuticals. Elsevier; 2022:483-510.
  • 77. Tiwari S, Talreja MS. A concept of nanotechnology in cosmetics: a complete overview. Adalya J. 2020;9(11):14-23.
  • 78. Altıokka İ, Üner M, Safety in Cosmetics and Cosmetovigilance, Current Regulations in Turkey. J Agent. 2022; 19(5): 610-617.
  • 79. Çankaya İİ. Obtaining Cosmetic Raw Materials from the Natural Resources of Turkey and Getting Them to the Industry. Current Persp Med Arom Plants. 2018;1(2):78-89.
  • 80. Gupta V, Mohapatra S, Mishra H, et al. Nanotechnology in cosmetics and cosmeceuticals—A review of latest advancements. Gels. 2022;8(3):173.
  • 81. Kose O, Erkekoglu P, Sabuncuoglu S, Kocer-Gumusel B. Evaluation of skin irritation potentials of different cosmetic products in Turkish market by reconstructed human epidermis model. Regul Toxicol Pharmacol. 2018;98:268-273.
  • 82. Effiong DE, Uwah TO, Jumbo EU, Akpabio AE. Nanotechnology in cosmetics: basics, current trends and safety concerns—A review. Adv Nano. 2019;9(1):1-22.
  • 83. Gadgil VR, Darak A, Patil SJ, et al. Recent developments in chemistry of sunscreens & their photostabilization. J Indian Chem Soc. 2023:100:100858.
  • 84. Geoffrey K, Mwangi A, Maru S. Sunscreen products: Rationale for use, formulation development and regulatory considerations. Saudi Pharm J. 2019;27(7):1009-1018.
Toplam 84 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Analitik Kimya (Diğer)
Bölüm Derlemeler
Yazarlar

Haticenur Kayacı 0009-0008-7637-1138

Müberra Andaç 0000-0001-7262-9762

Yayımlanma Tarihi 23 Kasım 2024
Gönderilme Tarihi 27 Mart 2024
Kabul Tarihi 29 Temmuz 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 4 Sayı: 2

Kaynak Göster

APA Kayacı, H., & Andaç, M. (2024). Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları. Ata-Kimya Dergisi, 4(2), 68-82. https://doi.org/10.62425/atakim.1459951
AMA Kayacı H, Andaç M. Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları. J Ata-Chem. Kasım 2024;4(2):68-82. doi:10.62425/atakim.1459951
Chicago Kayacı, Haticenur, ve Müberra Andaç. “Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları”. Ata-Kimya Dergisi 4, sy. 2 (Kasım 2024): 68-82. https://doi.org/10.62425/atakim.1459951.
EndNote Kayacı H, Andaç M (01 Kasım 2024) Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları. Ata-Kimya Dergisi 4 2 68–82.
IEEE H. Kayacı ve M. Andaç, “Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları”, J Ata-Chem, c. 4, sy. 2, ss. 68–82, 2024, doi: 10.62425/atakim.1459951.
ISNAD Kayacı, Haticenur - Andaç, Müberra. “Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları”. Ata-Kimya Dergisi 4/2 (Kasım 2024), 68-82. https://doi.org/10.62425/atakim.1459951.
JAMA Kayacı H, Andaç M. Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları. J Ata-Chem. 2024;4:68–82.
MLA Kayacı, Haticenur ve Müberra Andaç. “Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları”. Ata-Kimya Dergisi, c. 4, sy. 2, 2024, ss. 68-82, doi:10.62425/atakim.1459951.
Vancouver Kayacı H, Andaç M. Güneş Koruyucu Ürünlerde ZnO Nanopartiküllerinin Rolü: Güneşten Koruyucu Teknolojisinin Yenilikçi Boyutları. J Ata-Chem. 2024;4(2):68-82.

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