OTOJEN DİŞ KEMİK GREFTİNİN BİYOLOJİK ÖZELLİKLERİ VE KLİNİK KULLANIMI

Öz

Kemik dokunun tamiri ve yenilenmesinde, allogreft, ksenogreft ve sentetik kemik greftlerinin eksikliklerinin üstesinden gelebilecek ve otojen kemik greftlerine benzer kemik rejenerasyon kapasitesine sahip yeni materyaller geliştirmek için çalışmalar devam etmektedir. Otojen diş kemik greftleri, fiziksel ve biyolojik yapısı kemik doku ile benzer olan bir materyaldir. Bu greft, inorganik ve organik olmak üzere iki bileşene sahiptir. Organik yapı içerisinde yer alan kemik morfogenetik proteinleri, kollajen ve kollajen olmayan proteinler ile inorganik yapının oluşumunda bir iskelet görevi görür. İnorganik yapının büyük bir yüzdesini oluşturan hidroksiapatit kristalleri dokuya dayanıklılık kazandırır ve organik yapı ile birlikte yeni kemik doku oluşumunu sağlar. Bu derleme, geleneksel kemik greft materyallerine göre daha iyi bir alternatif olarak hizmet edebileceği düşünülen otojen diş kemik greftleri hakkında bilgi sunmaktadır. Anahtar kelimeler: Otojen diş kemik grefti, kemik ogmentasyonu, yeni geliştirilen kemik greft materyalleri BIOLOGICAL FEATURES AND CLINICAL USE OF AUTOGENOUS TOOTH BONE GRAFT ABSTRACT The studies focus on new bone grafts which as an alternative of allograft, xenograft and synthetic bone graft and, have a similar bone regeneration capacity with autogenous bone grafts. Autogenous tooth bone grafts are materials whose physical and biological structure is similar that of the bone tissue. This graft has two components, inorganic and organic. Organic structure that includes bone morphogenetic proteins, collagen and non-collagen proteins act as a scaffold for the formation of the inorganic structure. Hydroxyapatite crystals, which make up a large percentage of the inorganic structure, give the tissue durability and provide new bone tissue formation with the organic structure. This review provides knowledge on autogenous tooth bone grafts that may serve as a better alternative to conventional bone graft materials. Key words: Autogenous tooth bone graft; bone augmentation; novel bone grafting materials

Anahtar Kelimeler

• Otojen diş kemik grefti
• kemik ogmentasyonu
• novel bone grafting materials

Kaynakça

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