Kurşun, Civa, Kadmiyum: Çocuk Sağlığına Etkileri ve Temasın Belirlenmesinde Saç Örneklerinin Kullanımı

Öz

Ağır metaller yaygın kullanımları nedeniyle en zararlı çevresel kirleticilerdendir. Kurşun, civa ve kadmiyum çevresel kaynakları, vücuda alınış yolları, toksik etkileri ve vücutta saptanma yöntemleri iyi bilinen metallerdir. Çocukluk döneminde ağır metal temasının saptanmasında saç materyalinin kullanılması, toplanması, saklanması ve taşınması kolay ve düşük maliyetlidir. Bununla birlikte saçın alınacağı yer ve miktarının net olmaması, kontaminasyon riski, güvenilir referans aralıklarının olmayışı dezavantajlarıdır. Günümüzde kan ve saç düzeyleri ile büyüyen fetusta etkileri arasında ilişki için yeterli verisi olan tek element metil civadır. Bununla birlikte kurşun ve kadmiyum temasının ve toksik etkilerinin değerlendirmesinde saç örneklerinin kullanılması sınırlıdır. Çevresel teması göstermede saç analizinin iyi bir yöntem haline gelmesi için birçok bilimsel konunun aydınlatılmaya ihtiyacı vardır

Anahtar Kelimeler

• Kurşun
• Civa
• Kadmiyum
• Saç Örneği
• Çocuk

Lead, Mercury, Cadmium: Effects on Child Health and Using Hair Samples in Determination of Exposure

Öz

Heavy metals are the most harmful environmental pollutants, due to widespread use. Lead, mercury, and cadmium are well-known regard as environmental resources, ways of receiving the body, the toxic effects, detection methods in biological markers. Using hair sample have many advantages such as easily and noninvasively collected with minimal cost collection, and it is easily stored and transported to the laboratory for analysis. However, it have disadvantages risk of contamination, lack of reliable reference values, and no consensus exists on the length of the hair specimen to be collected, or the amount, or the position on scalp. Nowadays, methylmercury is the only element for which sufficient data exist to define the relationship between concentrations in blood, concentrations in hair, and effects on the target (the developing fetus). But, analysis of lead and cadmium in hair samples is limited to use for the exposure to lead and cadmium and their toxic effects. Many scientiŞc issues need to be highlighted before hair analysis can become a useful tool in understanding environmental exposures

Anahtar Kelimeler

• Lead
• Mercury
• Cadmium
• Hair sample
• Child

Kaynakça

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