Öz
Anahtar Kelimeler
Kaynakça
- O’Neill BM, Alessi AS, George EB, et al. Disseminated rhinocerebral mu- cormycosis: a case report and review of literature. J Oral Maxillofac Surg 2006; 64:326-333.
- Blitzer A, Lawson W, Meyers BR, et al. Patient survival factors in paranasal sinus mucormycosis. Laryngoscope 1980;90:635-648.
- Sugar AM. Mucormycosis. Clin Infect Dis 1992;14:126-129.
- Naussbaum ES, Holl WA. Rhinocerebral mucormycosis: changing patterns of disease. Surg Neurol 1994;41:152-156.
- Victor M, Ropper AH. Infections of the nervous system and sarcoidosis. In: Principles of neurology. 8th ed. New York: McGraw-Hill; 2005. p. 1110- 1177.
- Mohinra S, Mohinra S, Gupta R, et al. Rhinocerebral mucormycosis: the dis- ease spectrum in 27 patients. Mycosis 2007;50:290-296.
- Yohai RA, Bullock JD, Aziz AA, et al. Survival factors in rhino- orbital- cere- bral mucormycosis. Surv Ophthalmol 1994;39:3-22.
- Ladurner R, Brandacher G, Steurer W, et al. Lessons to be learned from a complicated case of rhinocerebral mu- cormycosis in a renal allograft reci- pient. Transpl Int 2003;16:885-889.
- Garg R, Grupta VV, Ashok L. Rhi- nomaxillary mucormycosis: A palatal ulcer. Contemp Clin Dent. 2011;2:119- 123.
- Thomas S, Singh VD, Vaithilimgam Y, et al. Rhinocerebral mucormycosis: a case report. Oral Maxillofac Surg. 2012; 16(2):233-236.
- Viterbo S, Fasolis M, Garzino-Demo P, et al. Management and outcomes of three cases of rhinocerebral mucormy- cosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112(6): e69-74
- Cortez KJ, Walsh TJ. Space-occupying fungal lesions. In Scheld WM, Whitley RJ, Marra CM, editors: Infections of the central nervous system, ed 3, Philadephia, Lippincott Willams & Wilkins; 2004. p. 713-733.
- Johnson RT, Griffin JW, McArthur JC. Fungal Infections. In: Current Therapy in Neurologic Disease. 7th ed. Philadephia: Mosby Inc; 2006. p. 161- 169.
- Roden MM, Zaoutis TE, Buchanan WL, et al. Epidemiology and outcome of zygomycosis: a review of 929 re- ported cases. Clin Infect Dis 2005;41:634-653.
- Elinav H, Zimhony O, Cohen MJ, et al. Rhinocerebral mucormycosis in pa- tients without predisposing medical conditions: a review of the literature. Clin Microbiol Infect 2009;15:693-697.
Öz
Rinoserebral mukormikozis nadir görülen, ilerleyici ve ölümcül olabilen oportunistik fungal bir
infeksiyondur. Yüksek mortalite ve morbiditeye sahiptir. Erken tanı, medikal ve cerrahi tedavi
prognozun düzelmesi için önemlidir. Biz, predispozan faktörü aplastik anemi ve akut myeloblastik
lösemi olan iki olgu sunduk. Mukormikozis, olgularımızın etkilenen gözünde oküler hareketlerde
bozulmaya, propitozise, kemozise ve hiperemiye neden olmuștur. Ayrıca ilk olgumuzda
mukormikozis nedeni ile trigeminal sinirin birinci ve ikinci dalıda etkilenmiștir. Her iki
olgumuzda da mukormikozis infeksiyonu histopatolojik olarak doğrulanmıștır. İlk olgumuzun
manyetik rezonans görüntülemesinde sol taraftaki maksiller, sfenoid ve etmoid sinuste
yumușak doku artıșı ve etkilenen bölge çevresindeki dura ve ekstraokuler kaslarda kontrast
tutulumu mevcuttur. İkinci olgunun orbitofrontal bilgisayarlı tomografisinde sol frontal, maksiller,
etmoid ve sfenoid sinuste radio-opasite ve sol etmoid sinusun kemik duvarında delikli
destruksiyon vardır. Her iki olgumuzda antifungal tedavi verilmesine rağmen ölmüștür. Mukormikozisin
bașarılı tedavisi için erken tanı, altta yatan predispozan risk faktörün düzelebilir
olması, cerrahi debridman ve erken antifugal tedavi gerekmektedir.
Anahtar Kelimeler
Rinoserebral mukormikozis oküler palsi presdispozan faktör erken tanı antifungal tedavi
Kaynakça
- O’Neill BM, Alessi AS, George EB, et al. Disseminated rhinocerebral mu- cormycosis: a case report and review of literature. J Oral Maxillofac Surg 2006; 64:326-333.
- Blitzer A, Lawson W, Meyers BR, et al. Patient survival factors in paranasal sinus mucormycosis. Laryngoscope 1980;90:635-648.
- Sugar AM. Mucormycosis. Clin Infect Dis 1992;14:126-129.
- Naussbaum ES, Holl WA. Rhinocerebral mucormycosis: changing patterns of disease. Surg Neurol 1994;41:152-156.
- Victor M, Ropper AH. Infections of the nervous system and sarcoidosis. In: Principles of neurology. 8th ed. New York: McGraw-Hill; 2005. p. 1110- 1177.
- Mohinra S, Mohinra S, Gupta R, et al. Rhinocerebral mucormycosis: the dis- ease spectrum in 27 patients. Mycosis 2007;50:290-296.
- Yohai RA, Bullock JD, Aziz AA, et al. Survival factors in rhino- orbital- cere- bral mucormycosis. Surv Ophthalmol 1994;39:3-22.
- Ladurner R, Brandacher G, Steurer W, et al. Lessons to be learned from a complicated case of rhinocerebral mu- cormycosis in a renal allograft reci- pient. Transpl Int 2003;16:885-889.
- Garg R, Grupta VV, Ashok L. Rhi- nomaxillary mucormycosis: A palatal ulcer. Contemp Clin Dent. 2011;2:119- 123.
- Thomas S, Singh VD, Vaithilimgam Y, et al. Rhinocerebral mucormycosis: a case report. Oral Maxillofac Surg. 2012; 16(2):233-236.
- Viterbo S, Fasolis M, Garzino-Demo P, et al. Management and outcomes of three cases of rhinocerebral mucormy- cosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112(6): e69-74
- Cortez KJ, Walsh TJ. Space-occupying fungal lesions. In Scheld WM, Whitley RJ, Marra CM, editors: Infections of the central nervous system, ed 3, Philadephia, Lippincott Willams & Wilkins; 2004. p. 713-733.
- Johnson RT, Griffin JW, McArthur JC. Fungal Infections. In: Current Therapy in Neurologic Disease. 7th ed. Philadephia: Mosby Inc; 2006. p. 161- 169.
- Roden MM, Zaoutis TE, Buchanan WL, et al. Epidemiology and outcome of zygomycosis: a review of 929 re- ported cases. Clin Infect Dis 2005;41:634-653.
- Elinav H, Zimhony O, Cohen MJ, et al. Rhinocerebral mucormycosis in pa- tients without predisposing medical conditions: a review of the literature. Clin Microbiol Infect 2009;15:693-697.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Mart 2012 |
| Yayımlandığı Sayı | Yıl 2012 Cilt: 65 Sayı: 3 |