D VİTAMİNİ

Öz

D vitamini, kemik yapımı, kalsiyum ve fosforun sindirim yollarında emilimi, kullanımı ve dengesi, kalsiyumun aktif taşınması, kalsiyum-bağlayıcı proteinlerin oluşumu ve çocuklarda özellikle büyüme için gerekli bir vitamindir. D vitamini, vücuda bitkisel ve hayvansal kaynaklı besinler yoluyla provitamin olarak alınır, güneş ışınlarının etkisiyle deride ve vücutta sentez edilir

Anahtar Kelimeler

• Kalsiyum, D vitamini, kalsitriol, kalsidiol, disbiyozis, hastalıklar, D vitamini eksikliği, UV, provitamin, VDR, kemik, hidroksilasyon

VITAMIN D

Öz

Vitamin D is essential vitamin for normal bone development and maintenance, absorbtion, metabolism and balance of calsium and phosphorus at digestive tract, active transport of calcium, producing od calcium binding protein and especially on for growing children. Vitamin D taken to body as herbal and animal sources as provitamin, synthesized in the skin upon exposure to sunlight and is then metabolized in the liver and kidney to the metabolically active form

Anahtar Kelimeler

• Calsium, Vitamin D, Calsitirol, calsidiol, dysbiozis, diseases, Vitamin D defficency, UV, provitamin, VDR, bone, hidroxilation

Kaynakça

1. http://www.naturalremedies.org/vitamin-d4/
2. Bikle DD. Vitamin D metabolism, mechanism of action, and clinical app- lications. Chem Biol. 2014;21(3):319-329
3. Volmer DA, Mendes LR, Stokes CS. Analysis of vitamin D metabolic mar- kers by mass spectrometry: Current techniques, limitations of the “gold standard” method, and anticipated future directions. Mass Spectrom Rev. 2015;34(1):2-23
4. Holick MF. Vitamin D: A millenium perspective. J Cell Biochem. 2003;88(2):296-307
5. Sutton AL, MacDonald PN. Vitamin D: more than a “bone-a-fide” hormo- ne. Mol Endocrinol. 2003;17(5):777-791.
6. Grober U, Spitz J, Reichrath J, Kisters K, Holick MF. Vitamin D: Update 2013: From rickets prophylaxis to general preventive healthcare. Derma- toendocrinol. 2013;5(3):331-347. (PubMed)
7. Sutton AL, MacDonald PN. Vitamin D: more than a “bone-a-fide” hormo- ne. Mol Endocrinol. 2003;17(5):777-791.
8. Liel Y, Shany S, Smirnoff P, Schwartz B Estrogen increases 1,25-dihydroxy- vitamin D receptors expression and bioresponse in the rat duodenal mu- cosa. Endocrinology. 1999 Jan;140(1):280-5.

9. Chen TC, Persons KS, Lu Z, Mathieu JS, Holick MF. An evaluation of the biologic activity and vitamin D receptor binding affinity of the photoiso- mers of vitamin D3 and previtamin D. J Nutr Biochem.2000; 11: 267-272.
10. 1 Boulch Le N, Cancela L, Miravet L. Cholecalciferol sulfate identification in human milk by HPLC. Steroids. 1982;39 (4): 391-398
11. Griffin MD, Xing N, Kumar R. Vitamin D and its analogs as regula- tors of immune activation and antigen presentation. Annu Rev Nutr. 2003;23:117-145
12. Borissova AM, Tankova T, Kirilov G, Dakovska L, Kovacheva R. The effect of vitamin D3 on insulin secretion and peripheral insulin sensitivity in type 2 diabetic patients. Int J Clin Pract. 2003;57(4):258-261.
13. Vitamin D Deficiency and Risk of Cardiovascular Disease. Circulation. Published online before print January 7, 2008.
14. Merke J, Hofmann W, Goldschmidt D, Ritz E. Demonstration of 1,25(OH)2 vitamin D3 receptors and actions in vascular smooth muscle cells in vit- ro. Calcif Tissue Int. 1987;41:112–114
15. Micronutrient Information Center-Linus Pauling Institude
16. Beslenme Bülteni (Prof. Dr. Ahmet Aydın)
17. Nazlıkul H. Gerçek Detoksu Keşfet
18. Nazlıkul H. Nöralterapi Kitabı Nobel Kitabevi 2010 İstanbul
19. DeLuca HF. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr. 2004;80(6 Suppl):1689S-1696S. (PubMed)
20. Fukumoto S. Phosphate metabolism and vitamin D. Bonekey Rep. 2014;3:497.
21. Nazlıkul H. Tamamlayıcı Tıp ve Regülasyon (Komplementär und Regulati- onsmedizin) S6-9 Barnat 5/2006
22. Nazlıkul H. Barnat Bilimsel Tamamlayıcı Tıp, Regülasyon ve Nöralterapi Dergisi, Fibromiyalji Yıl 2 Sayı 3 S: 10-22 Eylül 2007.