Comorbidity status of patients with lung cancer

Yıl 2010, Cilt: 1 Sayı: 1, 11 - 16, 05.04.2013

Sulhattin Arslan , İbrahim Akkurt

https://doi.org/10.12808/bcs.v1i1.3

Öz

Abstract

Aim: In this study, we aimed to investigate the associations between comorbidity status and age, gender, stage and histopathological type of tumors in patients with lung cancer. Methods: Age, gender, smoking status, stage, accompanying diseases, and histological types of 148 patients were recorded. The Charlson comorbidity index was used for definition and grading of comorbidity. Results: In 44.6% of our patients, there was at least one comorbid disease. When associations between Charlson comorbidity index and demographic variables, smoking status, histological type and stage of the tumor were investigated, following results were found: 45.5 % of men, 46.7% of the smokers, 56.3 % of undifferentiated and 52.6% of patients with squamous cell carcinoma, 48.2% and 49.2 % of widespread and advanced stages of lung cancers, respectively, had medical comorbidities. Conclusions: In our study, medical comorbidity was more common in men than in women, in smoker than in non-smokers, in undifferentiated and squamous cell carcinomas than in the other histological types. The relationship between comorbidity status and stage of the tumor supports the hypothesis of camouflage.

Keywords: Comorbidity, lung cancer, smoking

Özet

Akciğer kanserli hastaların komorbidite durumu

Amaç: Bu çalışmada amacımız akciğer kanseri hastalarında komorbiditenin yaş, cinsiyet, evre ve histopatolojik tipi ile olan ilişkisini incelemekti. Yöntem: Yüz kırk sekiz akciğer kanserli hastanın yaşları, cinsiyetleri, sigara içme durumları,  hastalık evreleri, eşlik eden hastalıkları ve histolojik tipleri kaydedildi. Komorbiditenin tanım ve derecelendirilmesinde Charlson komorbidite indeksi kullanıldı. Bulgular: Hastalarımızın %44,6'sında en az bir komorbid hastalığı vardı. Charlson indeksine göre komorbidite derecesinin cinsiyet, sigara içme durumu, histolojik tip, evre ile olan ilişkisi değerlendirildiğinde erkeklerin %45,5'inde, sigara içme öyküsü olanların %46,7'inde, squamöz hücreli karsinomların %52,6'sında, tiplendirme yapılamayanların 56,3'ünde,  yaygın ve ileri evreye sahip akciğer kanserli olguların sırasıyla %48,2 ve % 49,2'sinde medikal komorbidite tespit edildi. Sonuçlar: Bulgularımıza göre komorbidite, erkeklerde kadınlara göre, sigara içenlerde içmeyenlere göre, tiplendirilmeyen ve skuamöz hücreli karsinomu olanların diğer histolojik tipleri olanlara göre daha fazladır. Hastalarımızın komorbidite ve evre ilişkisi kamuflaj hipotezini desteklemektedir.

Anahtar sözcükler: komorbidite, akciğer kanseri, sigara içme

Anahtar Kelimeler

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Kaynakça

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