Primary giant cell tumor of soft tissue on mandibular region: a case report and literature review

Yıl 2013, Cilt: 2 Sayı: 2, 71 - 82, 08.09.2013

Fahrettin Göze , Ahmet Muslehiddinoğlu

https://doi.org/10.12808/bcs.v2i2.28

Öz

Abstract

Primary giant cell tumor of the soft tissue was first defined by Salm and Sissons as a tumoral lesion histologically identical to the giant cell tumor of the bone and clinically benign even though having some local recurrences. However, subsequent studies have demonstrated that besides benign forms, tumor also had potentially malignant and malignant forms. In this case, we evaluated a tumor seen on a woman at 27 years old and rare in location (mandibular region) and diagnosed as 'primary giant cell tumor of the soft tissue' (PGCT-ST). We also impressed on the differential diagnosis of the case by evaluating the morphological and immunohistochemical properties of the tumor. Moreover, since potentially malignant and malignant forms of the tumor were also defined, we reviewed the criteria of differential diagnosis and the literature again and tried to make the clinical behavior of the tumor clear.

Keywords: Low grade giant cell tumor, soft tissue, mandibular region

Özet

Yumuşak dokuların primer dev hücreli tümörü ilk olarak Salm ve Sissons tarafından histolojik olarak kemiğin dev hücreli tümörüne benzer ve klinik olarak bazı lokal rekürrensleri olsa da benign bir lezyon olarak tanımlanmıştır; ama daha sonraki çalışmalar benign formların yanında tümörün potansiyel olarak malign veya malign formlarının olduğunu göstermiştir. Bu olguda 27 yaşında bir kadında ve mandibuler bölge gibi nadir bir yerde saptanan yumuşak dokunun primer dev hücreli tümörü olarak tanımlanan bir tümör sunulmuştur. Bu olgu dolayısı ile bu tümörlerin morfolojik ve immünohistopatolojik özellikleri ele alınmıştır. Bu yaklaşımla tümörün ayırıcı tanısı literatür eşliğinde ele alınarak tümörün klinik özelliklerinin açıklanmasına çalışılmıştır.

Anahtar Sözcükler: Düşük dereceli dev hücreli tümör, yumuşak doku, mandibular bölge

Anahtar Kelimeler

Low grade giant cell tumor, soft tissue, mandibular region

Kaynakça

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