Chemical compositions of essential oil obtained from the fruits of Laser trilobum grown in Mersin

Abstract

Laser trilobum (L.) Borkh. is a perennial herbaceous plant growing naturally in some parts of Turkey. Its dried and ground fruits are called 'Kefe kimyonu'. Kefe cumin, from which essential oil is obtained from its fruits rich in nutrients, is not cultivated in our country. In this study, the amount of essential oil obtained from the fruits of kefe cumin and the components of these essential oils were determined. Kefe cumin (Laser trilobum) plant was obtained from Mersin region and the essential oils of its fruits were determined by clevenger aparatus and its components were determined by Gas Chromatography and Gas Chromatography-Mass Spectroscopy method. According to the research findings, the essential oil rate of the plant was determined as 4.4%, and it was determined that the main components of this essential oil were d-limonene and peryl aldehyde (with a total rate of 95.36%).

Keywords

• Mersin
• Kefe cumin
• Laser trilobum
• essential oil

Mersin’ de Yetişen Kefe Kimyonu (Laser trilobum) Meyvelerinden Elde Edilen Uçucu Yağın Kimyasal Bileşenleri

Abstract

Laser trilobum (L.) Borkh. Türkiye'nin bazı bölgelerinde doğal olarak yetişen çok yıllık otsu bir bitkidir. Kurutulmuş ve öğütülmüş meyveleri 'Kefe kimyonu' olarak adlandırılır. Besin elementleri yönünden zengin olan meyvelerinden uçucu yağ elde edilen kefe kimyonunun ülkemizde yetiştiriciliği yapılmamaktadır. Bu çalışma ile kefe kimyonu meyvelerinden elde edilen uçucu yağ miktarını ve bu uçucu yağların bileşenlerini belirlenmiştir. Kefe kimyonu (Laser trilobum) bitkisi Mersin yöresinden temin edilmiş olup meyvelerinin uçucu yağı clevenger cihazı ile bileşenleri ise Gaz Kromatografisi ve Gaz Kromatografisi-Kütle Spektroskopisi yöntemiyle belirlenmiştir. Araştırma bulgularına göre bitkinin uçucu yağ oranı %4,4 olarak tespit edilmiş olup bu uçucu yağın ana bileşenlerini d-limonen ve peril aldehitin (toplam %95,36 oranında) oluşturduğu belirlenmiştir.

Keywords

• Mersin
• Kefe kimyonu
• Laser trilobum
• uçucu yağ

Supporting Institution

Yok

References

1. [1] Turan, B. (1984). Türkiye`de Bitkilerle Tedavi. İstanbul Üniversitesi Yayınları.
2. [2] Senkardes, I., & Tuzlaci, E. (2014). Some Ethnobotanical Notes from Gundogmus District (Antalya/Turkey). Journal of Marmara University Institute of Health Sciences, 4(2), 1.
3. [3] Tutin, T. G. ., Heywood, V. H. ., Burges, N. A. ., Moore, D. M. ., Valentine, D. H. ., Walters, S. M. ., & Webb, D. A. (1981). Flora Europaea. Volume 2. Rosaceae to Umbelliferae (3rd edition) (W. R. 1928-1971 Ernst (ed.)). Madroño; a West American journal of botany.
4. [4] Parlatan, A., Sariçoban, C., & Özcan, M. M. (2009). Chemical composition and antimicrobial activity of the extracts of Kefe cumin (Laser trilobum L.) fruits from different regions. International Journal of Food Sciences and Nutrition, 60(7), 606–617. https://doi.org/10.3109/09637480801993938
5. [5] Kivanç, M., & Akgül, A. (1991). Effect of Laser trilobum spice on natural microflora of köfte, a Turkish ground meat product. Food / Nahrung, 35(2), 149–154. https://doi.org/10.1002/food.19910350206
6. [6] Drobac, M., Petrović, S., Milenković, M., Couladis, M., Kukić-Marković, J., & Niketić, M. (2017). Composition and antimicrobial properties of essential oils of laser trilobum rhizomes and fruits. Natural Product Communications, 12(3), 445–448. https://doi.org/10.1177/1934578x1701200335
7. [7] Güneş, S., Savran, A., Paksoy, M. Y., Koşar, M., & Çakılcıoğlu, U. (2017). Ethnopharmacological survey of medicinal plants in Karaisalı and its surrounding (Adana-Turkey). Journal of Herbal Medicine, 8(April), 68–75. https://doi.org/10.1016/j.hermed.2017.04.002
8. [8] Bulut, G., Tuzlacı, E., Doğan, A., & Şenkardeş, İ. (2014). A review of edible plants on the Turkish Apiaceae species. Journal of Faculty Pharmacy of Istanbul University, 44(2), 251-262–262.

9. [ 9] Harmatha, J., Budešínský, M., Vokáč, K., Kostecká, P., Kmoníčková, E., & Zídek, Z. (2013). Trilobolide and related sesquiterpene lactones from Laser trilobum possessing immunobiological properties. Fitoterapia, 89(1), 157–166. https://doi.org/10.1016/j.fitote.2013.05.025
10. [10] Huml, L., Jurášek, M., Mikšátková, P., Zimmermann, T., Tomanová, P., Buděšínský, M., Rottnerová, Z., Šimková, M., Harmatha, J., Kmoníčková, E., Lapčík, O., & Drašar, P. B. (2017). Immunoassay for determination of trilobolide. Steroids, 117, 105–111. https://doi.org/10.1016/j.steroids.2016.08.019
11. [11] Ebrahimzadeh, M. A., Nabavi, S. M., Nabavi, S. F., Eslami, B., & Rahmani, Z. (2010). Antioxidant and antihaemolytic activities of the leaves of Kefe cumin (Laser trilobum L) Umbelliferae. Tropical Journal of Pharmaceutical Research, 9(5), 441–449. https://doi.org/10.4314/tjpr.v9i5.61053
12. [12] Burdock, G. ., & Fenaroli, G. (1995). Fenaroli’s Handbook of Flavour Ingredients, trid ed. CRC Press.
13. [13] Meriçli, F., & Meriçli, A. H. (1986). Laser Trılobum ve Cumınum Cymınum Meyvalarının Uçucu Yağları. Mar.Üniv.Ecz.Der, 2(1), 85–95.
14. [14] Masoudi, S., Ameri, N., Rustaiyan, A., Moradalizadeh, M., & Azar, P. A. (2005). Volatile constituents of three umbelliferae herbs: Azilia eryngioedes (pau) hedge et lamond, laser trilobum (l.) borkh. and falcaria falcarioides (bornm. et wolff) growing wild in Iran. Journal of Essential Oil Research, 17(1), 98–100. https://doi.org/10.1080/10412905.2005.9698843
15. [15] Akgül, A. (1992). The essential oil composition of turkish Laser trilobum (L.) Borkh. Fruits. Journal of Essential Oil Research, 4(1), 89–90. https://doi.org/10.1080/10412905.1992.9698019
16. [16] Baser, K. H. C., Özek, T., Tümen, G., & Sezik, E. (1993). Composition of the essential oils of Turkish Origanum species with commercial importance. Journal of Essential Oil Research, 5(6), 619–623. https://doi.org/10.1080/10412905.1993.9698294
17. [17] Brunke, E. ., Hammerschmidt, F. ., & Köster, F. H. (1990). The essential oil of Laser trilobum L. Dragoco Report, 37, 182–188.
18. [18] Hobbs, C. A., Taylor, S. V., Beevers, C., Lloyd, M., Bowen, R., Lillford, L., Maronpot, R., & Hayashi, S. mo. (2016). Genotoxicity assessment of the flavouring agent, perillaldehyde. Food and Chemical Toxicology, 97, 232–242. https://doi.org/10.1016/j.fct.2016.08.029
19. [19] Jecfa. (2003). Safety evaluation of certain food additives. In: Fifty-ninth Meeting ofthe Joint FAO/WHO Expert Committee on Food Additives.WHO Food AdditiveSeries, no. 50.
20. [20] Shuge, T., Xiaoying, Z., Fan, Z., Dongqing, A., & Tao, Y. (2010). Essential Oil Composition of the Dracocephalum moldavica L from Xinjiang in China. Pharmacognosy Research, 1(4), 172–174.
21. [21] Tian, J., Wang, Y., Lu, Z., Sun, C., Zhang, M., Zhu, A., & Peng, X. (2016). Perillaldehyde, a Promising Antifungal Agent Used in Food Preservation, Triggers Apoptosis through a Metacaspase-Dependent Pathway in Aspergillus flavus. Journal of Agricultural and Food Chemistry, 64(39), 7404–7413. https://doi.org/10.1021/acs.jafc.6b03546
22. [22] Ji, W. W., Wang, S. Y., Ma, Z. Q., Li, R. P., Li, S. S., Xue, J. S., Li, W., Niu, X. X., Yan, L., Zhang, X., Fu, Q., Qu, R., & Ma, S. P. (2014). Effects of perillaldehyde on alternations in serum cytokines and depressive-like behavior in mice after lipopolysaccharide administration. Pharmacology Biochemistry and Behavior, 116, 1–8. https://doi.org/10.1016/j.pbb.2013.10.026
23. [23] Bassoli, A., Borgonovo, G., Caimi, S., Scaglioni, L., Morini, G., Moriello, A. S., Marzo, V. Di, & Petrocellis, L. De. (2009). Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens. Bioorganic and Medicinal Chemistry, 17(4), 1636–1639. https://doi.org/10.1016/j.bmc.2008.12.057
24. [24] Fan, Y., Li, C., Peng, X., Jiang, N., Hu, L., Gu, L., Zhu, G., Zhao, G., & Lin, J. (n.d.). Keratitis by Activating the Nrf2 / HO-1 Signaling Pathway and Inhibiting Dectin-1-Mediated Inflammation.
25. [25] Luciana, N. A., Patrícia, S., Ricardo, G. A., Grace, A. A. D., Andressa, da S., Melina, A., Ricardo, L. C. A. J., Maria, C. S. L., Claudia, O. P., Adriana, A. C., & Damiao, P. de S. (2018). Evaluation of cytotoxic and antitumor activity of perillaldehyde 1,2-epoxide. Journal of Medicinal Plants Research, 12(30), 590–600. https://doi.org/10.5897/jmpr2018.6699
26. [26] Zielińska-Błajet, M., Pietrusiak, P., & Feder-Kubis, J. (2021). Selected monocyclic monoterpenes and their derivatives as effective anticancer therapeutic agents. International Journal of Molecular Sciences, 22(9). https://doi.org/10.3390/ijms22094763
27. [27] Yu, X., Lin, H., Wang, Y., Lv, W., Zhang, S., Qian, Y., Deng, X., Feng, N., Yu, H., & Qian, B. (2018). D-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer. OncoTargets and Therapy, 11, 1833–1847. https://doi.org/10.2147/OTT.S155716
28. [28] Sun, jidong. (2007). D-Limonene: safety and clinical applications. Altern Med Rev, 12(3), 259–264.
29. [29] Crowell, P. L., Elson, C. E., Bailey, H. H., Elegbede, A., & J D Haag, M. N. G. (1994). Human metabolism of the experimental cancer therapeutic agent d-limonene. Cancer Chemother Pharmacol, 35(1), 31–37.
30. [30] Chizzola, R. (2007). Laser trilobum Grown ın The wıld ın Vıenna. 43(4), 396–397.