Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Hidroksil radikali ve Hipokloröz asiti Süpürme Aktivitesi

Mahire Bayramoğlu; Ferda Candan

doi:10.17798/bitlisfen.473761

Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Hidroksil radikali ve Hipokloröz asiti Süpürme Aktivitesi

Abstract

Çalışmada Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Etanol ekstraktının total antioksidan kapasitesi ile hidroksil radikal(OH^.) ve hipokloröz asiti(HOCI) süpürme aktivitesinin değerlendirilmesi amaçlandı. M. longifolia subsp. typhoides var. typhoides total antioksidan kapasitesi 569±8.57 mg AAE/gr olarak belirlendi. Bitki ekstraktının hidroksil radikali ve hipokloröz asit oluşumunu yüzde elli inhibe eden derişimleri ise sırasıyla IC₅₀:71.85±1.79 ve IC₅₀:199.30±3.97 µg/mL olarak tesbit edildi. Sonuç olarak M. longifolia subsp. typhoides var. typhoides etanol ekstraktının total antioksidan kapasitesi ve radikal süpürme aktivitesi değerlendirildiğinde bitkinin potensiyel bir doğal antioksidan kaynağı olabileceği söylenebilir. Ayrıca, oksidatif strese bağlı olarak ortaya çıkabilecek birçok hastalığın önlenmesi veya tedavisinde terapötik ajanlar olarak oldukça yüksek etkiye sahip olabileceği düşünülmektedir.

Keywords

Hidroksil radikal,Hipokloröz asit

References

1. Özgen U., Mavi A., Terzi Z., Yιldιrιm A., Coşkun M., Houghton P.J. 2006. Antioxidant properties of some medicinal Lamiaceae (Labiatae) species, Pharmaceutical biology, 44(2): 107-112.
2. Birben E., Sahiner U.M., Sackesen C., Erzurum S., Kalayci O. 2012. Oxidative stress and antioxidant defense, World Allergy Organization Journal, 5(1): 9.
3. Kasprzak K.S. 2002. Oxidative DNA and protein damage in metal-induced toxicity and carcinogenesis1, 3, Free Radical Biology and Medicine, 32(10): 958-967.
4. Iwasaki A., Gagnon C. 1992. Formation of reactive oxygen species in spermatozoa of infertile patients, Fertility and sterility, 57(2): 409-416.
5. Letelier M.E., Molina-Berríos A., Cortés-Troncoso J., Jara-Sandoval J., Holst M., Palma K., González-Lira V. 2008. DPPH and oxygen free radicals as pro-oxidant of biomolecules, Toxicology in vitro, 22(2): 279-286.
6. Alscher R.G., Donahue J.L., Cramer C.L. 1997. Reactive oxygen species and antioxidants: relationships in green cells, Physiologia Plantarum, 100(2): 224-233.
7. Sevindik M., Akgul H., Pehlivan M., Selamoglu Z. 2017. Determination of therapeutic potential of Mentha longifolia ssp. Longifolia, Fresen Environ Bull, 26, 4757-4763.
8. Mikaili P., Mojaverrostami S., Moloudizargari M., Aghajanshakeri S. 2013. Pharmacological and therapeutic effects of Mentha Longifolia L. and its main constituent, menthol, Ancient science of life, 33(2): 131.

9. Mimica-Dukic N., Popovic M., Jakovljevic V., Szabo A., Gašic O. 1999. Pharmacological studies of Mentha longifolia phenolic extracts. II. Hepatoprotective activity, Pharmaceutical biology, 37(3): 221-224.
10. Prieto P, Pineda M, Aguilar M. 1999. Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E, Anal Biochem, 269: 337-341.
11. Kunchandy E., Rao M.N.A. 1990. Oxygen radical scavenging activity of curcumin,Int. J.Pharmacog, 58: 237-240.
12. Aruoma OI, Halliwell B. 1987. Action of hypochlorous acid on the antioxidant protective enzymes superoxide dismutase, catalase and glutathione peroxidase. Biochem J 248: 973– 97.
13. Pedraza‐Chaverrí J., Arriaga‐Noblecía G., Medina‐Campos O.N. 2007. Hypochlorous acid scavenging capacity of garlic. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 21(9); 884-888.
14. Gulluce M., Sahin F., Sokmen M., Ozer H., Daferera D., Sokmen A., Ozkan, H. Antimicrobial and antioxidant properties of the essential oils and methanol extract from Mentha longifolia L. ssp. longifolia. Food chemistry, 2007;103(4): 1449-1456.
15. Singh S., Das S.S., Singh G., Perotti M., Schuff C., Catalán C.A. 2015. In vitro antioxidant potentials and chemistry of essential oils and oleoresins from fresh and sun-dried Mentha longifolia L. Journal of Essential Oil Research, 27(1): 61-69.
16. Djeridane A., Yousfi M., Nadjemi B., Boutassouna D., Stocker P., Vidal N. 2006. Antioxidant activity of some Algerian medicinal plants extracts containing phenolic compounds. Food chemistry, 97(4): 654-660.
17. Abootalebian M., Keramat J., Kadivar M., Ahmadi F., Abdinian M. 2016. Comparison of total phenolic and antioxidant activity of different Mentha spicata and M. longifolia accessions, Annals of Agricultural Sciences, 61(2): 175-179.
18. Stanisavljević D.M., Stojičević S.S., Đorđević S.M., Zlatković B.P., Veličković D.T., Karabegović I.T., Lazić M.L. 2012. Antioxidant activity, the content of total phenols and flavonoids in the ethanol extracts of Mentha longifolia (L.) Hudson dried by the use of different techniques, Chemical Industry and Chemical Engineering Quarterly, 18(3): 411-420.
19. Hajlaoui H., Trabelsi N., Noumi E., Snoussi M., Fallah H., Ksouri R., Bakhrouf A. 2009. Biological activities of the essential oils and methanol extract of tow cultivated mint species (Mentha longifolia and Mentha pulegium) used in the Tunisian folkloric medicine. World Journal of Microbiology and Biotechnology, 25(12): 2227-2238.
20. Fatiha B., Didier H., Naima G., Khodir M., Martin K., Léocadie K., Pierre D. 2015. Phenolic composition, in vitro antioxidant effects and tyrosinase inhibitory activity of three Algerian Mentha species: M. spicata (L.), M. pulegium (L.) and M. rotundifolia (L.) Huds (Lamiaceae), Industrial crops and products, 74, 722-730.
21. Orhan F., Barış Ö., Yanmış D., Bal T., Güvenalp Z., Güllüce M. 2012. Isolation of some luteolin derivatives from Mentha longifolia (L.) Hudson subsp. longifolia and determination of their genotoxic potencies. Food chemistry, 135(2): 764-769.
22. Bahadori M.B., Zengin G., Bahadori S., Dinparast L., Movahhedin N. 2018. Phenolic composition and functional properties of wild mint (Mentha longifolia var. calliantha (Stapf) Briq.), International Journal of Food Properties, 21(1): 183-193
23. Battino M., Bullon P., Wilson M., Newman H. 1999. Oxidative injury and inflammatory periodontal diseases: the challenge of anti-oxidants to free radicals and reactive oxygen species, Critical Reviews in Oral Biology & Medicine, 10(4): 458-476.
24. Valko M., Rhodes C., Moncol J., Izakovic M.M., Mazur M. 2006. Free radicals, metals and antioxidants in oxidative stress-induced cancer, Chemico-biological interactions, 160(1): 1-40.
25. Pullar J.M., Vissers M.C., Winterbourn C.C. 2000. Living with a killer: the effects of hypochlorous acid on mammalian cells, IUBMB life, 50(4‐5): 259-266.
26. Mika D., Guruvayoorappan C. 2011. Myeloperoxidase: the yin and yang in tumour progression, Journal of experimental therapeutics & oncology, 9(2):93-100.
27. Panasenko O.M., Gorudko I.V., Sokolov A.V. 2013. Hypochlorous acid as a precursor of free radicals in living systems, Biochemistry (Moscow), 78(13): 1466-1489
28. Senkardes I., Tuzlaci E. 2014. Some Ethnobotanical Notes from Gundogmus District (Antalya/Turkey). Clinical and Experimental Health Sciences, 4(2): 63.
29. Arasan S., Kaya I. 2015. Some important plants belonging to asteraceae family used in folkloric medicine in Savur (Mardin/Turkey) area and their application areas. J Food Nutr Res, 3:337-340.
30. Dekigai H., Murakami M., Kita T. 1995. Mechanism ofhelicobacter pylori-associated gastric mucosal injury. Digestive diseases and sciences, 40(6); 1332-1339.
31. Lapenna D., Cuccurullo F. 1996. Hypochlorous acid and its pharmacological antagonism: an update Picture, General pharmacology, 27(7):1145-1147.

Details

Primary Language

Turkish

Subjects

-

Journal Section

Research Article

Authors

Mahire Bayramoğlu ^*
0000-0001-5150-5402
Türkiye

Ferda Candan This is me

Publication Date

June 28, 2019

Submission Date

October 23, 2018

Acceptance Date

March 12, 2019

Published in Issue

Year 2019 Volume: 8 Number: 2

DOI

https://doi.org/10.17798/bitlisfen.473761

IZ

https://izlik.org/JA78JD23DC

Cite

RIS / Bibtex

APA

Bayramoğlu, M., & Candan, F. (2019). Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Hidroksil radikali ve Hipokloröz asiti Süpürme Aktivitesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, 8(2), 406-412. https://doi.org/10.17798/bitlisfen.473761

AMA

1.Bayramoğlu M, Candan F. Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Hidroksil radikali ve Hipokloröz asiti Süpürme Aktivitesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi. 2019;8(2):406-412. doi:10.17798/bitlisfen.473761

Chicago

Bayramoğlu, Mahire, and Ferda Candan. 2019. “Mentha Longifolia (L.) Hudson Subsp. Typhoides (Briq.) Harley Var. Typhoides’in Hidroksil Radikali Ve Hipokloröz Asiti Süpürme Aktivitesi”. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi 8 (2): 406-12. https://doi.org/10.17798/bitlisfen.473761.

EndNote

Bayramoğlu M, Candan F (June 1, 2019) Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Hidroksil radikali ve Hipokloröz asiti Süpürme Aktivitesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi 8 2 406–412.

IEEE

[1]M. Bayramoğlu and F. Candan, “Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Hidroksil radikali ve Hipokloröz asiti Süpürme Aktivitesi”, Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, vol. 8, no. 2, pp. 406–412, June 2019, doi: 10.17798/bitlisfen.473761.

ISNAD

Bayramoğlu, Mahire - Candan, Ferda. “Mentha Longifolia (L.) Hudson Subsp. Typhoides (Briq.) Harley Var. Typhoides’in Hidroksil Radikali Ve Hipokloröz Asiti Süpürme Aktivitesi”. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi 8/2 (June 1, 2019): 406-412. https://doi.org/10.17798/bitlisfen.473761.

JAMA

1.Bayramoğlu M, Candan F. Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Hidroksil radikali ve Hipokloröz asiti Süpürme Aktivitesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi. 2019;8:406–412.

MLA

Bayramoğlu, Mahire, and Ferda Candan. “Mentha Longifolia (L.) Hudson Subsp. Typhoides (Briq.) Harley Var. Typhoides’in Hidroksil Radikali Ve Hipokloröz Asiti Süpürme Aktivitesi”. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, vol. 8, no. 2, June 2019, pp. 406-12, doi:10.17798/bitlisfen.473761.

Vancouver

1.Mahire Bayramoğlu, Ferda Candan. Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Hidroksil radikali ve Hipokloröz asiti Süpürme Aktivitesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi. 2019 Jun. 1;8(2):406-12. doi:10.17798/bitlisfen.473761

Cited By

Determination of Antioxidant-Antiradical Activity and Vitamin C Content of Peucedanum longifolium Waldst. & Kit

Türk Doğa ve Fen Dergisi

https://doi.org/10.46810/tdfd.1743281