Mentha longifolia (L.) Hudson subsp. Typhoides (Briq.) Harley var. Typhoides’in Hidroksil radikali ve Hipokloröz asiti Süpürme Aktivitesi

Yıl 2019, , 406 - 412, 28.06.2019

Mahire Bayramoğlu , Ferda Candan

https://doi.org/10.17798/bitlisfen.473761

Öz

Çalışmada Mentha
longifolia (L.) Hudson subsp.
Typhoides (Briq.) Harley var.
Typhoides’in Etanol
ekstraktının total antioksidan kapasitesi ile hidroksil radikal(OH^.)
ve hipokloröz asiti(HOCI) süpürme aktivitesinin değerlendirilmesi amaçlandı. M. longifolia
subsp. typhoides var. typhoides total antioksidan kapasitesi
569±8.57 mg AAE/gr  olarak belirlendi.
Bitki ekstraktının hidroksil radikali ve hipokloröz asit oluşumunu yüzde elli
inhibe eden derişimleri ise sırasıyla IC₅₀:71.85±1.79 ve IC₅₀:199.30±3.97
µg/mL olarak tesbit edildi. Sonuç olarak M. longifolia subsp. typhoides var. typhoides etanol ekstraktının total antioksidan
kapasitesi ve radikal süpürme aktivitesi değerlendirildiğinde bitkinin
potensiyel bir doğal antioksidan kaynağı olabileceği söylenebilir. Ayrıca, oksidatif
strese bağlı olarak ortaya çıkabilecek birçok hastalığın önlenmesi veya
tedavisinde terapötik ajanlar olarak oldukça yüksek etkiye sahip olabileceği
düşünülmektedir.

Anahtar Kelimeler

Hidroksil radikal, Hipokloröz asit

Kaynakça

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