Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi

Ümit Yırtıcı

doi:10.17798/bitlisfen.484336

Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi

Abstract

Çiçeklenme döneminde toplanan Centaurea fenzlii Reichardt’ın toprak üstü kısımları farklı polariteye sahip çözücülerde maserasyon yöntemi kullanılarak çözüldü ve ekstreleri elde edildi. Çalışmalara metanol ekstresi ile devam edildi. Metanol ekstresinin toplam fenolik ve flavonoid içerikleri sırasıyla, 16,72 mg GAE/g ka ve 173,16 mg KAE/g ka olarak belirlendi. Antioksidan kapasiteleri demir indirgeyici gücü (FRAP) için 0,256 mmol TE/g ka, bakır indirgeyici gücü (CUPRAC) için 0,878 mmol TE/g ka, ABTS için 0,354 mmol TE/g ka ve DPPH için 0,661 mmol TE/g ka olarak saptandı. Ayrıca, ekstrelerinin kolinesteraz, α-amilaz, α-glukozidaz ve tirozinaz enzimlerine karşı inhibe edici etkileri de belirlendi. Enzim inhibisyon etkisi sırasıyla, α-Glukozidaz için 0,331 mmol AKE/g ka, α-Amilaz için 0,354 mmol AKE/g ka, AChE için 0,367 mmol GAE/g ka, BChE için 0,878 mmol GAE/g ka ve Tirozinaz için mmol 0,256 KE/g ka olarak bulundu.

Keywords

Centaurea fenzlii Reichardt,Antioksidan,Enzim İnhibisyonu

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Details

Primary Language

Turkish

Subjects

-

Journal Section

Research Article

Authors

Ümit Yırtıcı ^*
Türkiye

Publication Date

March 12, 2019

Submission Date

November 16, 2018

Acceptance Date

January 23, 2019

Published in Issue

Year 2019 Volume: 8 Number: 1

DOI

https://doi.org/10.17798/bitlisfen.484336

IZ

https://izlik.org/JA24WT23FH

Cite

RIS / Bibtex

APA

Yırtıcı, Ü. (2019). Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, 8(1), 66-73. https://doi.org/10.17798/bitlisfen.484336

AMA

1.Yırtıcı Ü. Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi. 2019;8(1):66-73. doi:10.17798/bitlisfen.484336

Chicago

Yırtıcı, Ümit. 2019. “Centaurea Fenzlii Reichardt Özütünün Antioksidan Özellikleri Ve Enzim İnhibisyon Etkisinin Belirlenmesi”. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi 8 (1): 66-73. https://doi.org/10.17798/bitlisfen.484336.

EndNote

Yırtıcı Ü (March 1, 2019) Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi 8 1 66–73.

IEEE

[1]Ü. Yırtıcı, “Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi”, Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, vol. 8, no. 1, pp. 66–73, Mar. 2019, doi: 10.17798/bitlisfen.484336.

ISNAD

Yırtıcı, Ümit. “Centaurea Fenzlii Reichardt Özütünün Antioksidan Özellikleri Ve Enzim İnhibisyon Etkisinin Belirlenmesi”. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi 8/1 (March 1, 2019): 66-73. https://doi.org/10.17798/bitlisfen.484336.

JAMA

1.Yırtıcı Ü. Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi. 2019;8:66–73.

MLA

Yırtıcı, Ümit. “Centaurea Fenzlii Reichardt Özütünün Antioksidan Özellikleri Ve Enzim İnhibisyon Etkisinin Belirlenmesi”. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, vol. 8, no. 1, Mar. 2019, pp. 66-73, doi:10.17798/bitlisfen.484336.

Vancouver

1.Ümit Yırtıcı. Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi. 2019 Mar. 1;8(1):66-73. doi:10.17798/bitlisfen.484336

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