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Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry

Cilt: 2 Sayı: 1 31 Mayıs 2024
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Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry

Öz

Cancer treatment involves a range of treatments aimed at stopping or slowing the uncontrolled growth of abnormal cells in the body. These methods include surgical intervention, radiotherapy, chemotherapy, targeted drugs, and immunotherapy. Cancer treatment can be applied depending on the patient's type, stage, and general health condition. A multidisciplinary approach is taken during cancer treatment, which requires oncologists, surgeons, radiation specialists, and other healthcare professionals to work together. Treatment aims to destroy or control cancer cells, minimize side effects, and improve the patient's quality of life. In this article, Yozgat Bozok University's Department of Chemistry will provide information about the synthesis and activity studies of active pharmaceutical substances that can be used in cancer treatment

Anahtar Kelimeler

Cancer treatment, Activity studies, Pharmaceutical substances, Antiproliferative

Kaynakça

  1. İ. Koca, A. Özgür, K. Açikalin Coşkun, and Y. Tutar, "Synthesis and Anticancer Activity of Acyl Thioureas Bearing Pyrazole Moiety," Bioorg. Med. Chem., vol. 21, no. 13, pp. 3859–3865, Apr. 2013, doi: 10.1016/j.bmc.2013.04.021.
  2. İ. Koca, M. Gümüş, A. Özgür, A. Dişli, and Y. Tutar, "A Novel Approach to Inhibit Heat Shock Response as Anticancer Strategy by Coumarine Compounds Containing Thiazole Skeleton," Anti-Cancer Agents Med. Chem., vol. 15, no. 7, pp. 916–930, Sept. 2015, doi: 10.2174/1871520615666150407155623.
  3. İ. Koca, A. Özgür, M. Er, M. Gümüş, K. Açikalin Coşkun, and Y. Tutar, "Design and Synthesis of Pyrimidinyl Acyl Thioureas as Novel Hsp90 Inhibitors in Invasive Ductal Breast Cancer and its Bone Metastasis," Eur. J. Med. Chem., vol. 122, pp. 280–290, Jun. 2016, doi: 10.1016/j.ejmech.2016.06.032.
  4. M. Gümüş, A. Özgür, L. Tutar, A. Dişli, İ. Koca, and Y. Tutar, "Design, Synthesis, and Evaluation of Heat Shock Protein 90 Inhibitors in Human Breast Cancer and Its Metastasis," Curr Pharm Biotechnol., vol. 17, no. 14, pp. 1231–1245, Nov. 2016, doi:10.2174/1389201017666161031105815.
  5. E. G. Sağlam, S. Akkoç, Y. Zorlu, E. Bulat, and A. Akgün, “New Phenanthroline Nickel(II) Organodithio-Phosphorus Complexes: Syntheses, Structural Characterizations and In Vitro Cytotoxic Activity Studies,” Polyhedron, vol. 199, no. 115097, 1–13, Feb. 2021, doi: 10.1016/j.poly.2021.115097.
  6. E. G. Sağlam, S. Akkoç, C. T. Zeyrek, H. Dal, and O. Tutsak, “New Heterobimetallic Nickel(II) Ferrocenyldithiophosphonato Complexes: Syntheses, Characterization, Antiproliferative Activity and X-ray, DFT, Molecular Docking Studies on Trans-Bis-[O-3-methyl-1-butyl-(ferrocenyl) Dithiophosphonato] Nickel(II),” Inorg. Chim. Acta, vol. 514, pp. 1–11, 2021, doi: 10.1016/j.ica.2020.119991.
  7. İ. Koca, V. Kamaci, C. Özsoy, Y. Sert, İ. Kani, L. Tutar, and Y. Tutar, “Pyrazolyl-Benzoxazinone Derivatives as Dual Hsp Inhibitors in Human Breast Cancer,” ChemistrySelect, vol. 7, no. 19, May. 2022, pp. 1–10, doi: 10.1002/slct.202200359.
  8. İ. E., Kıbrız, S. Akkoç, Y. Sert, Ü. Çay, and Ş. H. Üngören, "Synthesis, Antiproliferative Activity, Molecular Docking Studies of Hydrazone Functionalised Thioparabanic Acid and Rhodanine Analogues," Phosphorus Sulfur Silicon Relat. Elem., vol. 197, no. 9, pp. 918–926, Apr. 2022, doi: 10.1080/10426507.2022.2046578.

Kaynak Göster

APA
Kıbrız, İ. E., & Yakan, M. (2024). Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry. Bozok Journal of Science, 2(1), 1-5. https://izlik.org/JA86NE87DZ
AMA
1.Kıbrız İE, Yakan M. Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry. BJS. 2024;2(1):1-5. https://izlik.org/JA86NE87DZ
Chicago
Kıbrız, İbrahim Evren, ve Mehmet Yakan. 2024. “Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry”. Bozok Journal of Science 2 (1): 1-5. https://izlik.org/JA86NE87DZ.
EndNote
Kıbrız İE, Yakan M (01 Mayıs 2024) Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry. Bozok Journal of Science 2 1 1–5.
IEEE
[1]İ. E. Kıbrız ve M. Yakan, “Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry”, BJS, c. 2, sy 1, ss. 1–5, May. 2024, [çevrimiçi]. Erişim adresi: https://izlik.org/JA86NE87DZ
ISNAD
Kıbrız, İbrahim Evren - Yakan, Mehmet. “Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry”. Bozok Journal of Science 2/1 (01 Mayıs 2024): 1-5. https://izlik.org/JA86NE87DZ.
JAMA
1.Kıbrız İE, Yakan M. Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry. BJS. 2024;2:1–5.
MLA
Kıbrız, İbrahim Evren, ve Mehmet Yakan. “Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry”. Bozok Journal of Science, c. 2, sy 1, Mayıs 2024, ss. 1-5, https://izlik.org/JA86NE87DZ.
Vancouver
1.İbrahim Evren Kıbrız, Mehmet Yakan. Synthesis and Activity Studies of Active Pharmaceutical Substances That Can Be Used in Cancer Treatment by Yozgat Bozok University Department of Chemistry. BJS [Internet]. 01 Mayıs 2024;2(1):1-5. Erişim adresi: https://izlik.org/JA86NE87DZ