A Severe Complication of Accidental Epidural Administration of Glutaraldehyde

Yıl 2009, Cilt: 2009 Sayı: 1, 83 - 86, 01.01.2009

ALKIN Çolak Turan Ege CAVİDAN Arar Cavidan Arar VOLKAN Yüksel Enver Duran

https://izlik.org/JA82ZC88PR

Öz

In a patient operated for left femoropopliteal bypass under epidural anesthesia, 3 ml of 3% glutaraldehyde solution was administered through the epidural catheter at the postoperative sixth hour accidentally. Following glutaraldehyde administration, the patient developed paraplegia in addition to systemic symptoms such as hypotension, tachycardia, nausea and vomiting. At the end of the first year, neurologic symptoms didn't improve despite medical treatment and rehabilitation program. Turkish Başlık: Glutaraldehidin Kazara Epidural Uygulanmasının Ağır Komplikasyonu Anahtar Kelimeler: Glutaraldehid; epidural; analjezi; parapleji Epidural anestezi altında sol femoropopliteal bypass uygulanan hastaya ameliyat sonrası altıncı saatte epidural kateter yoluyla kazara 3 ml %3 glutaraldehid solüsyonu uygulandı. Glutaraldehid uygulamasını takiben hastada hipotansiyon, taşikardi, bulantı ve kusma gibi sistemik semptomlara ek olarak parapleji gelişti. Bir yıllık medikal tedavi ve rehabilitasyon programı sonunda nörolojik semptomlarda iyileşme olmadı.

Anahtar Kelimeler

Glutaraldehyde; epidural; analgesia; paraplegia

Glutaraldehidin Kazara Epidural Uygulanmasının Ağır Komplikasyonu

https://izlik.org/JA82ZC88PR

Öz

Epidural anestezi altında sol femoropopliteal bypass uygulanan hastaya ameliyat sonrası altıncı saatte epidural kateter yoluyla kazara 3 ml %3 glutaraldehid solüsyonu uygulandı. Glutaraldehid uygulamasını takiben hastada hipotansiyon, taşikardi, bulantı ve kusma gibi sistemik semptomlara ek olarak parapleji gelişti. Bir yıllık medikal tedavi ve rehabilitasyon programı sonunda nörolojik semptomlarda iyileşme olmadı.

Anahtar Kelimeler

Glutaraldehid , epidural , analjezi , parapleji

Kaynakça

• Wu CL, Thomsen RW. Effect of postoperative epidural analgesia on patient outcomes. Techniques in Regional Anesthesia and Pain Management 2003;7:140-7.
• Ballantyne JC, McKenna JM, Ryder E. Epidural analgesia-experience of 5628 patients in a large teaching hospital derived through audit. Acute Pain 2003;4:89-97.
• Moore JM. Epidural analgesia and clinical outcomes. Seminars in Anesthesia, Perioperative Medicine and Pain 2003;22:197-208.
• Haetzman M, Stickle B. Epidural analgesia for postoperative pain. Current Anaesthesia and Critical Care 1999;10:140-6.
• Horlocker TT, Wedel DJ. Neurologic complications of spinal and epidural anesthesia. Reg Anesth Pain Med 2000;25:83-98.
• Albright GA, Forster RM. The safety and efficacy of combined spinal and epidural analgesia/anesthesia (6,002 blocks) in a community hospital. Reg Anesth Pain Med 1999;24:117-25.
• Rieder E, Seebacher G, Kasimir MT, Eichmair E, Winter B, Dekan B, et al. Tissue engineering of heart valves: decellularized porcine and human valve scaffolds differ importantly in residual potential to attract monocytic cells. Circulation 2005;111:2792-7.
• Kim SS, Lim SH, Cho SW, Gwak SJ, Hong YS, Chang BC, et al. Tissue engineering of heart valves by recellularization of glutaraldehyde-fixed porcine valves using bone marrow-derived cells. Exp Mol Med 2006;38:273-83.
• Karpelowsky JS, Maske CP, Sinclair-Smith C, Rode H. Glutaraldehyde-induced bowel injury after laparoscopy. J Pediatr Surg 2006;41:23-5.
• Kietzmann D, Foth H, Geng WP, Rathgeber J, Gundert-Remy U, Kettler D. Transpulmonary disposition of prilocaine, mepivacaine, and bupivacaine in humans in the course of epidural anaesthesia. Acta Anaesthesiol Scand 1995;39:885-90.