BibTex RIS Kaynak Göster

Endometriosis and Implantation

Yıl 2007, Cilt: 2007 Sayı: 2, 90 - 97, 01.02.2007

Öz

Implantation is a complex process by which the embryo attaches to the endometrium. The human endometrium becomes receptive to the embryo during the luteal phase of the menstrual cycle under the influence of steroid hormones and paracrine factors originating from endometrial cells and the embryo. Several paracrine factors influencing the implantation include leukemia inhibitory factor (LIF) and interleukin (IL)-11. Moreover, timely development of pinopodes, and expression of integrins and Hox genes in endometrium, and oocyte quality also determines the implantation outcome. Endometriosis is a common gynecologic disorder and estimated that 25 to 50% of infertile women have endometriosis. Although the mechanisms contributing to infertility are poorly understood, accumulating evidence suggests that altered folliculogenesis, sperm dysfunction, impaired fertilization, toxicity against early embryonic development, defective implantation, and poor oocyte quality with decreased ability to implant may be the contributing factors in some endometriosis patients. Turkish Başlık: Endometriosis ve implantasyon Anahtar Kelimeler: İmplantasyon; endometriosis; infertilite; oosit kalitesi İmplantasyon, embriyonun endometriuma yerleşmesinin gerçekleştiği kompleks bir işlemdir. İnsan endometriumu; endometrial hücreler ve embriyodan kaynaklanan steroid hormonlar ve parakrin faktörlerin etkisi altında, luteal faz süresince embriyoyu kabul etmeye hazır hale gelir. Lösemi inhibitor faktör (LİF) ve interlökin (İL)-11'de dahil olmak üzere, pek çok parakrin faktör implantasyonu etkiler. Bunun yanısıra endometriyumda gelişen pinopodlar, integrinler, HOX genleri ve aynı zamanda oosit kalitesi de implantasyon sonucunu belirler. Endometriosis; yaygın bir jinekolojik hastalıktır ve infertil kadınların yaklaşık %25-50'si endometriosislidir. İnfertiliteye sebep olan mekanizmalar tam olarak anlaşılamamış olmasına rağmen, bu konu hakkındaki genel kanı; normal olmayan folikülogenez, sperm disfonksiyonu, implantasyon başarısızlığı, erken dönem embriyo gelişimine karşı oluşan toksisite, implante olma yeteneği azalmış düşük oosit kalitesinin bazı endometriosisli hastalarda infertiliteye neden olan etkili faktörler olabileceği yönündedir.

Kaynakça

  • Berkkanoglu M, Arici A. Immunology and endometriosis. Am J Reprod Immunol 2003;50:48-59.
  • Jamieson DJ, Steege JF. The prevalence of dysmenor- rhea, dyspareunia, pelvic pain, and irritable bowel syndrome in primary care practices. Obstet Gynecol 1996;87:55-8.
  • Houston DE. Evidence for the risk of pelvic endometriosis by age, race and socioeconomic sta- tus. Epidemiol Rev 1984;6:167-91.
  • Strathy JH, Molgaard CA, Coulam CB, Melton LJ. Endometriosis and infertility: a laparoscopic study of endometriosis among fertile and infertile women. Fertil Steril 1982;38:667-72.
  • Tummon IS, Maclin VM, Radwanska E, Binor Z, Dmowski WP. Occult ovulatory dysfunction in women with minimal endometriosis or unexplained infertility. Fertil Steril 1988;50:716-20.
  • Dmowski WP, Radwanska E, Binor Z, Rana N. Mild endometriosis and ovulatory dysfunction: effect of danazol treatment on success of ovulation induc- tion. Fertil Steril 1986;46:784-9.
  • Soldati G, Piffaretti-Yanez A, Campana A, Marchini M, Luerti M, Balerna M. Effect of peritoneal fluid on sperm motility and velocity distribution using objec- tive measurements. Fertil Steril 1989;52:113-9.
  • Mahadevan MM, Trounson AO, Leeton JF. The rela- tionship of tubal blockage, infertility of unknown cause, suspected male infertility, and endometriosis to success of in vitro fertilization and embryo trans- fer. Fertil Steril 1983;40:755-62.
  • Wardle PG, Mitchell JD, McLaughlin EA, Ray BD, McDermott A, Hull MG. Endometriosis and ovula- tory disorder: reduced fertilisation in vitro com- pared with tubal and unexplained infertility. Lancet 1985;2:236-9.
  • Damewood MD, Hesla JS, Schlaff WD, Hubbard M, Gearhart JD, Rock JA. Effect of serum from patients with minimal to mild endometriosis on mouse embryo development in vitro. Fertil Steril 1990; 54:917-20.
  • Simón C, Gómez E, Mir A, De los Santos MJ, Pellicer A. Glucocorticoid treatment decreases sera embry- otoxicity in endometriosis patients. Fertil Steril 1992; 58:284-9.
  • Matson PL, Yovich JL. The treatment of infertility associated with endometriosis by in vitro fertiliza- tion. Fertil Steril 1986;46:432-4.
  • Simón C, Gutiérrez A, Vidal A, de los Santos MJ, Tarín JJ, Remohí J, et al. Outcome of patients with endometriosis in assisted reproduction: results from in-vitro fertilization and oocyte donation. Hum Reprod 1994;9:725-9.
  • Seli E, Berkkanoglu M, Arici A. Pathogenesis of endometriosis. Obstet Gynecol Clin North [Am] 2003;30:41-61.
  • Hill JA, Faris HM, Schiff I, Anderson DJ. Characterization of leukocyte subpopulations in the peritoneal fluid of women with endometriosis. Fertil Steril 1988;50:216-22.
  • Fakih H, Baggett B, Holtz G, Tsang KY, Lee JC, Williamson HO. Interleukin-1: a possible role in the infertility associated with endometriosis. Fertil Steril 1987;47:213-7.
  • Hill JA, Anderson DJ. Lymphocyte activity in the presence of peritoneal fluid from fertile women and infertile women with and without endometriosis. Am J Obstet Gynecol 1989;161:861-4.
  • Mori H, Sawairi M, Nakagawa M, Itoh N, Wada K, Tamaya T. Peritoneal fluid interleukin-1 beta and tumor necrosis factor in patients with benign gyne- cologic disease. Am J Reprod Immunol 1991;26:62-7.
  • Arici A, Tazuke SI, Attar E, Kliman HJ, Olive DL. Interleukin-8 concentration in peritoneal fluid of patients with endometriosis and modulation of interleukin-8 expression in human mesothelial cells. Mol Hum Reprod 1996;2:40-5.
  • Ryan IP, Tseng JF, Schriock ED, Khorram O, Landers DV, Taylor RN. Interleukin-8 concentrations are ele- vated in peritoneal fluid of women with endometriosis. Fertil Steril 1995;63:929-32.
  • Arici A, Oral E, Attar E, Tazuke SI, Olive DL. Monocyte chemotactic protein-1 concentration in peritoneal fluid of women with endometriosis and its modulation of expression in mesothelial cells. Fertil Steril 1997;67:1065-72.
  • Taketani Y, Kuo TM, Mizuno M. Comparison of cytokine levels and embryo toxicity in peritoneal fluid in infertile women with untreated or treated endometriosis. Am J Obstet Gynecol 1992;167:265-70.
  • Khorram O, Taylor RN, Ryan IP, Schall TJ, Landers DV. Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometrio- sis. Am J Obstet Gynecol 1993;169:1545-9.
  • McLaren J, Prentice A, Charnock-Jones DS, Millican SA, Müller KH, Sharkey AM, et al. Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids. J Clin Invest 1996;98:482-9.
  • Navarro J, Garrido N, Remohi J, Pellicer A. How does endometriosis affect infertility? Obstet Gynecol Clin North [Am] 2003;30:181-92.
  • Pellicer A, Albert C, Mercader A, Bonilla-Musoles F, Remohi J, Simon C. The follicular and endocrine environment in women with endometriosis: local and systemic cytokine production. Fertil Steril 1998; 70:425-31.
  • Carlberg M, Nejaty J, Fröysa B, Guan Y, Söder O, Bergqvist A. Elevated expression of tumour necrosis factor alpha in cultured granulosa cells from women with endometriosis. Hum Reprod 2000;15:1250-5.
  • Abaé M, Glassberg M, Majercik MH, Yoshida H, Vestal R, Puett D. Immunoreactive endothelin-1 con- centrations in follicular fluid of women with and without endometriosis undergoing in vitro fertiliza- tion-embryo transfer. Fertil Steril 1994;61:1083-7.
  • Oral E, Seli E, Bahtiyar MO, Jones EE, Arici A. Growth-regulated alpha expression in human pre- ovulatory follicles and ovarian cells. Am J Reprod Immunol 1997;38:19-25.
  • Lee KS, Joo BS, Na YJ, Yoon MS, Choi OH, Kim WW. Relationships between concentrations of tumor necrosis factor-alpha and nitric oxide in follicular fluid and oocyte quality. J Assist Reprod Genet 2000; 17:222-8.
  • Van Blerkom J, Antczak M, Schrader R. The devel- opmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: association with vascular endothelial growth factor levels and perifollicular blood flow characteristics. Hum Reprod 1997;12:1047-55.
  • Kasson BG, Gorospe WC. Effects of interleukins 1, 2 and 3 on follicle-stimulating hormone-induced dif- ferentiation of rat granulosa cells. Mol Cell Endocrinol 1989;62:103-11.
  • Roby KF, Terranova PF. Effects of tumor necrosis fac- tor-alpha in vitro on steroidogenesis of healthy and atretic follicles of the rat: theca as a target. Endocrinology 1990;126:2711-8.
  • Barnhart K, Dunsmoor-Su R, Coutifaris C. Effect of endometriosis on in vitro fertilization. Fertil Steril 2002;77:1148-55.
  • Mahutte NG, Arici A. New advances in the under- standing of endometriosis related infertility. J Reprod Immunol 2002;55:73-83.
  • Nakahara K, Saito H, Saito T, Ito M, Ohta N, Takahashi T, Hiroi M. The incidence of apoptotic bodies in membrana granulosa can predict progno- sis of ova from patients participating in in vitro fer- tilization programs. Fertil Steril 1997;68:312-7.
  • Saito H, Seino T, Kaneko T, Nakahara K, Toya M, Kurachi H. Endometriosis and oocyte quality. Gynecol Obstet Invest 2002;53:46-51.
  • Abu-Musa A, Takahashi K, Kitao M. The effect of serum obtained before and after treatment for endometriosis on in vitro development of two-cell mouse embryos. Fertil Steril 1992;57:1098-102.
  • Morcos RN, Gibbons WE, Findley WE. Effect of peri- toneal fluid on in vitro cleavage of 2-cell mouse embryos: possible role in infertility associated with endometriosis. Fertil Steril 1985;44:678-83.
  • Prough SG, Aksel S, Gilmore SM, Yeoman RR. Peritoneal fluid fractions from patients with endometriosis do not promote two-cell mouse embryo growth. Fertil Steril 1990;54:927-30.
  • Martinez-Roman S, Balasch J, Creus M, Fabregues F, Carmona F, Vilella R, et al. Immunological factors in endometriosis-associated reproductive failure: stud- ies in fertile and infertile women with and without endometriosis. Hum Reprod 1997;12:1794-9.
  • Brizek CL, Schlaff S, Pellegrini VA, Frank JB, Worrilow KC. Increased incidence of aberrant mor- phological phenotypes in human embryogenesis-an association with endometriosis. J Assist Reprod Genet 1995;12:106-12.
  • Pellicer A, Oliveira N, Ruiz A, Remohí J, Simón C. Exploring the mechanism(s) of endometriosis-relat- ed infertility: an analysis of embryo development and implantation in assisted reproduction. Hum Reprod 1995;10 Suppl 2:91-7.
  • Tanbo T, Omland A, Dale PO, Abyholm T. In vitro fertilization/embryo transfer in unexplained infer- tility and minimal peritoneal endometriosis. Acta Obstet Gynecol Scand 1995;74:539-43.
  • Giudice LC. Potential biochemical markers of uter- ine receptivity. Hum Reprod 1999;14 Suppl 2:3-16.
  • Navot D, Scott RT, Droesch K, Veeck LL, Liu HC, Rosenwaks Z. The window of embryo transfer and the efficiency of human conception in vitro. Fertil Steril 1991;55:114-8.
  • Cavagna M, Mantese JC. Biomarkers of endometrial receptivity-a review. Placenta 2003;24 Suppl B:S39-47.
  • Lessey BA. The role of the endometrium during embryo implantation. Hum Reprod 2000;15:39-50.
  • Edwards RG. Clinical approaches to increasing uter- ine receptivity during human implantation. Hum Reprod 1995;10:60-6.
  • Taylor HS, Vanden Heuvel GB, Igarashi P. A con- served Hox axis in the mouse and human female reproductive system: late establishment and persis- tent adult expression of the Hoxa cluster genes. Biol Reprod 1997;57:1338-45.
  • Taylor HS, Arici A, Olive D, Igarashi P. HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium. J Clin Invest 1998;101:1379-84.
  • Salehnia M. Different pattern of pinopodes expres- sion in stimulated mouse endometrium. Exp Anim 2005;54:349-52.
  • Nikas G. Cell-surface morphological events relevant to human implantation. Hum Reprod 1999;14:37-44.
  • Garcia-Velasco JA, Simon C, Ardiles G. Assessment of endometrial response to HRT using the detection of pinopodes in women with endometriosis under- going oocyte donation. In: 4th Meeting of the American Society of Reproductive Medicine; October 4-9, 1998; San Francisco, California, USA; 1998. p. 242.
  • Taylor HS. The role of HOX genes in human implan- tation. Hum Reprod Update 2000;6:75-9.
  • Taylor HS, Bagot C, Kardana A, Olive D, Arici A. HOX gene expression is altered in the endometrium of women with endometriosis. Hum Reprod 1999; 14:1328-31.
  • Daftary GS, Taylor HS. EMX2 gene expression in the female reproductive tract and aberrant expression in the endometrium of patients with endometriosis. J Clin Endocrinol Metab 2004;89:2390-6.
  • Lessey BA, Damjanovich L, Coutifaris C, Castelbaum A, Albelda SM, Buck CA. Integrin adhe- sion molecules in the human endometrium. Correlation with the normal and abnormal menstru- al cycle. J Clin Invest 1992;90:188-95.
  • Adams EC, Hertig AT, Rock J. A description of 34 human ova within the first 17 days of development. Am J Anat 1956;98:435-93.
  • Navot D, Bergh PA, Williams M, Garrisi GJ, Guzman I, Sandler B, et al. An insight into early reproductive processes through the in vivo model of ovum dona- tion. J Clin Endocrinol Metab 1991;72:408-14.
  • Lessey BA, Castelbaum AJ, Sawin SW, Buck CA, Schinnar R, Bilker W, et al. Aberrant integrin expres- sion in the endometrium of women with endometrio- sis. J Clin Endocrinol Metab 1994;79:643-9.
  • Lessey BA, Young SL. Integrins and other cell adhe- sion molecules in endometrium and endometriosis. Semin Reprod Endocrinol 1997;15:291-9.
  • Cakmak H, Schatz F, Huang ST, Buchwalder L, Rahman M, Arici A, et al. Progestin suppresses thrombin- and interleukin-1beta-induced inter- leukin-11 production in term decidual cells: implica- tions for preterm delivery. J Clin Endocrinol Metab 2005;90:5279-86.
  • Seli E, Kayisli UA, Cakmak H, Bukulmez O, Bildirici I, Guzeloglu-Kayisli O, et al. Removal of hydrosalp- inges increases endometrial leukaemia inhibitory factor (LIF) expression at the time of the implanta- tion window. Hum Reprod 2005;20:3012-7.
  • Bilinski P, Roopenian D, Gossler A. Maternal IL- 11Ralpha function is required for normal decidua and fetoplacental development in mice. Genes Dev 1998;12:2234-43.
  • Robb L, Li R, Hartley L, Nandurkar HH, Koentgen F, Begley CG. Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uter- ine response to implantation. Nat Med 1998;4:303-8.
  • Stewart CL, Kaspar P, Brunet LJ, Bhatt H, Gadi I, Köntgen F, et al. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature 1992;359:76-9.
  • Aghajanova L, Stavreus-Evers A, Nikas Y, Hovatta O, Landgren BM. Coexpression of pinopodes and leukemia inhibitory factor, as well as its receptor, in human endometrium. Fertil Steril 2003;79:808-14.
  • Cork BA, Li TC, Warren MA, Laird SM. Interleukin- 11 (IL-11) in human endometrium: expression throughout the menstrual cycle and the effects of cytokines on endometrial IL-11 production in vitro. J Reprod Immunol 2001;50:3-17.
  • Cullinan EB, Abbondanzo SJ, Anderson PS, Pollard JW, Lessey BA, Stewart CL. Leukemia inhibitory fac- tor (LIF) and LIF receptor expression in human en- dometrium suggests a potential autocrine/paracrine function in regulating embryo implantation. Proc Natl Acad Sci USA 1996;93:3115-20.
  • Dimitriadis E, Stoikos C, Stafford-Bell M, Clark I, Paiva P, Kovacs G, et al. Interleukin-11, IL-11 recep- toralpha and leukemia inhibitory factor are dysreg- ulated in endometrium of infertile women with endometriosis during the implantation window. J Reprod Immunol 2006;69:53-64.
  • Inoue M, Kobayashi Y, Honda I, Awaji H, Fujii A. The impact of endometriosis on the reproductive outcome of infertile patients. Am J Obstet Gynecol 1992;167:278-82.
  • Dmowski WP, Rana N, Michalowska J, Friberg J, Papierniak C, el-Roeiy A. The effect of endometrio- sis, its stage and activity, and of autoantibodies on in vitro fertilization and embryo transfer success rates. Fertil Steril 1995;63:555-62.
  • Olivennes F, Feldberg D, Liu HC, Cohen J, Moy F, Rosenwaks Z. Endometriosis: a stage by stage anal- ysis-the role of in vitro fertilization. Fertil Steril 1995; 64:392-8.
  • Pal L, Shifren JL, Isaacson KB, Chang Y, Leykin L, Toth TL. Impact of varying stages of endometriosis on the outcome of in vitro fertilization-embryo transfer. J Assist Reprod Genet 1998;15:27-31.
  • Bukulmez O, Yarali H, Gurgan T. The presence and extent of endometriosis do not effect clinical preg- nancy and implantation rates in patients undergoing intracytoplasmic sperm injection. Eur J Obstet Gynecol Reprod Biol 2001;96:102-7.
  • Azem F, Lessing JB, Geva E, Shahar A, Lerner-Geva L, Yovel I, et al. Patients with stages III and IV endometriosis have a poorer outcome of in vitro fer- tilization-embryo transfer than patients with tubal infertility. Fertil Steril 1999;72:1107-9.
  • Diaz I, Navarro J, Blasco L, Simon C, Pellicer A, Remohi J. Impact of stage III-IV endometriosis on recipients of sibling oocytes: matched case-control study. Fertil Steril 2000;74:31-4.
  • Remohi J, Ardiles G, Garcia-Velasco JA, Gaitan P, Simon C, Pellicer A. Endometrial thickness and serum oestradiol concentrations as predictors of outcome in oocyte donation. Hum Reprod 1997;12:2271-6.

Endometriosis ve implantasyon

Yıl 2007, Cilt: 2007 Sayı: 2, 90 - 97, 01.02.2007

Öz

Kaynakça

  • Berkkanoglu M, Arici A. Immunology and endometriosis. Am J Reprod Immunol 2003;50:48-59.
  • Jamieson DJ, Steege JF. The prevalence of dysmenor- rhea, dyspareunia, pelvic pain, and irritable bowel syndrome in primary care practices. Obstet Gynecol 1996;87:55-8.
  • Houston DE. Evidence for the risk of pelvic endometriosis by age, race and socioeconomic sta- tus. Epidemiol Rev 1984;6:167-91.
  • Strathy JH, Molgaard CA, Coulam CB, Melton LJ. Endometriosis and infertility: a laparoscopic study of endometriosis among fertile and infertile women. Fertil Steril 1982;38:667-72.
  • Tummon IS, Maclin VM, Radwanska E, Binor Z, Dmowski WP. Occult ovulatory dysfunction in women with minimal endometriosis or unexplained infertility. Fertil Steril 1988;50:716-20.
  • Dmowski WP, Radwanska E, Binor Z, Rana N. Mild endometriosis and ovulatory dysfunction: effect of danazol treatment on success of ovulation induc- tion. Fertil Steril 1986;46:784-9.
  • Soldati G, Piffaretti-Yanez A, Campana A, Marchini M, Luerti M, Balerna M. Effect of peritoneal fluid on sperm motility and velocity distribution using objec- tive measurements. Fertil Steril 1989;52:113-9.
  • Mahadevan MM, Trounson AO, Leeton JF. The rela- tionship of tubal blockage, infertility of unknown cause, suspected male infertility, and endometriosis to success of in vitro fertilization and embryo trans- fer. Fertil Steril 1983;40:755-62.
  • Wardle PG, Mitchell JD, McLaughlin EA, Ray BD, McDermott A, Hull MG. Endometriosis and ovula- tory disorder: reduced fertilisation in vitro com- pared with tubal and unexplained infertility. Lancet 1985;2:236-9.
  • Damewood MD, Hesla JS, Schlaff WD, Hubbard M, Gearhart JD, Rock JA. Effect of serum from patients with minimal to mild endometriosis on mouse embryo development in vitro. Fertil Steril 1990; 54:917-20.
  • Simón C, Gómez E, Mir A, De los Santos MJ, Pellicer A. Glucocorticoid treatment decreases sera embry- otoxicity in endometriosis patients. Fertil Steril 1992; 58:284-9.
  • Matson PL, Yovich JL. The treatment of infertility associated with endometriosis by in vitro fertiliza- tion. Fertil Steril 1986;46:432-4.
  • Simón C, Gutiérrez A, Vidal A, de los Santos MJ, Tarín JJ, Remohí J, et al. Outcome of patients with endometriosis in assisted reproduction: results from in-vitro fertilization and oocyte donation. Hum Reprod 1994;9:725-9.
  • Seli E, Berkkanoglu M, Arici A. Pathogenesis of endometriosis. Obstet Gynecol Clin North [Am] 2003;30:41-61.
  • Hill JA, Faris HM, Schiff I, Anderson DJ. Characterization of leukocyte subpopulations in the peritoneal fluid of women with endometriosis. Fertil Steril 1988;50:216-22.
  • Fakih H, Baggett B, Holtz G, Tsang KY, Lee JC, Williamson HO. Interleukin-1: a possible role in the infertility associated with endometriosis. Fertil Steril 1987;47:213-7.
  • Hill JA, Anderson DJ. Lymphocyte activity in the presence of peritoneal fluid from fertile women and infertile women with and without endometriosis. Am J Obstet Gynecol 1989;161:861-4.
  • Mori H, Sawairi M, Nakagawa M, Itoh N, Wada K, Tamaya T. Peritoneal fluid interleukin-1 beta and tumor necrosis factor in patients with benign gyne- cologic disease. Am J Reprod Immunol 1991;26:62-7.
  • Arici A, Tazuke SI, Attar E, Kliman HJ, Olive DL. Interleukin-8 concentration in peritoneal fluid of patients with endometriosis and modulation of interleukin-8 expression in human mesothelial cells. Mol Hum Reprod 1996;2:40-5.
  • Ryan IP, Tseng JF, Schriock ED, Khorram O, Landers DV, Taylor RN. Interleukin-8 concentrations are ele- vated in peritoneal fluid of women with endometriosis. Fertil Steril 1995;63:929-32.
  • Arici A, Oral E, Attar E, Tazuke SI, Olive DL. Monocyte chemotactic protein-1 concentration in peritoneal fluid of women with endometriosis and its modulation of expression in mesothelial cells. Fertil Steril 1997;67:1065-72.
  • Taketani Y, Kuo TM, Mizuno M. Comparison of cytokine levels and embryo toxicity in peritoneal fluid in infertile women with untreated or treated endometriosis. Am J Obstet Gynecol 1992;167:265-70.
  • Khorram O, Taylor RN, Ryan IP, Schall TJ, Landers DV. Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometrio- sis. Am J Obstet Gynecol 1993;169:1545-9.
  • McLaren J, Prentice A, Charnock-Jones DS, Millican SA, Müller KH, Sharkey AM, et al. Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids. J Clin Invest 1996;98:482-9.
  • Navarro J, Garrido N, Remohi J, Pellicer A. How does endometriosis affect infertility? Obstet Gynecol Clin North [Am] 2003;30:181-92.
  • Pellicer A, Albert C, Mercader A, Bonilla-Musoles F, Remohi J, Simon C. The follicular and endocrine environment in women with endometriosis: local and systemic cytokine production. Fertil Steril 1998; 70:425-31.
  • Carlberg M, Nejaty J, Fröysa B, Guan Y, Söder O, Bergqvist A. Elevated expression of tumour necrosis factor alpha in cultured granulosa cells from women with endometriosis. Hum Reprod 2000;15:1250-5.
  • Abaé M, Glassberg M, Majercik MH, Yoshida H, Vestal R, Puett D. Immunoreactive endothelin-1 con- centrations in follicular fluid of women with and without endometriosis undergoing in vitro fertiliza- tion-embryo transfer. Fertil Steril 1994;61:1083-7.
  • Oral E, Seli E, Bahtiyar MO, Jones EE, Arici A. Growth-regulated alpha expression in human pre- ovulatory follicles and ovarian cells. Am J Reprod Immunol 1997;38:19-25.
  • Lee KS, Joo BS, Na YJ, Yoon MS, Choi OH, Kim WW. Relationships between concentrations of tumor necrosis factor-alpha and nitric oxide in follicular fluid and oocyte quality. J Assist Reprod Genet 2000; 17:222-8.
  • Van Blerkom J, Antczak M, Schrader R. The devel- opmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: association with vascular endothelial growth factor levels and perifollicular blood flow characteristics. Hum Reprod 1997;12:1047-55.
  • Kasson BG, Gorospe WC. Effects of interleukins 1, 2 and 3 on follicle-stimulating hormone-induced dif- ferentiation of rat granulosa cells. Mol Cell Endocrinol 1989;62:103-11.
  • Roby KF, Terranova PF. Effects of tumor necrosis fac- tor-alpha in vitro on steroidogenesis of healthy and atretic follicles of the rat: theca as a target. Endocrinology 1990;126:2711-8.
  • Barnhart K, Dunsmoor-Su R, Coutifaris C. Effect of endometriosis on in vitro fertilization. Fertil Steril 2002;77:1148-55.
  • Mahutte NG, Arici A. New advances in the under- standing of endometriosis related infertility. J Reprod Immunol 2002;55:73-83.
  • Nakahara K, Saito H, Saito T, Ito M, Ohta N, Takahashi T, Hiroi M. The incidence of apoptotic bodies in membrana granulosa can predict progno- sis of ova from patients participating in in vitro fer- tilization programs. Fertil Steril 1997;68:312-7.
  • Saito H, Seino T, Kaneko T, Nakahara K, Toya M, Kurachi H. Endometriosis and oocyte quality. Gynecol Obstet Invest 2002;53:46-51.
  • Abu-Musa A, Takahashi K, Kitao M. The effect of serum obtained before and after treatment for endometriosis on in vitro development of two-cell mouse embryos. Fertil Steril 1992;57:1098-102.
  • Morcos RN, Gibbons WE, Findley WE. Effect of peri- toneal fluid on in vitro cleavage of 2-cell mouse embryos: possible role in infertility associated with endometriosis. Fertil Steril 1985;44:678-83.
  • Prough SG, Aksel S, Gilmore SM, Yeoman RR. Peritoneal fluid fractions from patients with endometriosis do not promote two-cell mouse embryo growth. Fertil Steril 1990;54:927-30.
  • Martinez-Roman S, Balasch J, Creus M, Fabregues F, Carmona F, Vilella R, et al. Immunological factors in endometriosis-associated reproductive failure: stud- ies in fertile and infertile women with and without endometriosis. Hum Reprod 1997;12:1794-9.
  • Brizek CL, Schlaff S, Pellegrini VA, Frank JB, Worrilow KC. Increased incidence of aberrant mor- phological phenotypes in human embryogenesis-an association with endometriosis. J Assist Reprod Genet 1995;12:106-12.
  • Pellicer A, Oliveira N, Ruiz A, Remohí J, Simón C. Exploring the mechanism(s) of endometriosis-relat- ed infertility: an analysis of embryo development and implantation in assisted reproduction. Hum Reprod 1995;10 Suppl 2:91-7.
  • Tanbo T, Omland A, Dale PO, Abyholm T. In vitro fertilization/embryo transfer in unexplained infer- tility and minimal peritoneal endometriosis. Acta Obstet Gynecol Scand 1995;74:539-43.
  • Giudice LC. Potential biochemical markers of uter- ine receptivity. Hum Reprod 1999;14 Suppl 2:3-16.
  • Navot D, Scott RT, Droesch K, Veeck LL, Liu HC, Rosenwaks Z. The window of embryo transfer and the efficiency of human conception in vitro. Fertil Steril 1991;55:114-8.
  • Cavagna M, Mantese JC. Biomarkers of endometrial receptivity-a review. Placenta 2003;24 Suppl B:S39-47.
  • Lessey BA. The role of the endometrium during embryo implantation. Hum Reprod 2000;15:39-50.
  • Edwards RG. Clinical approaches to increasing uter- ine receptivity during human implantation. Hum Reprod 1995;10:60-6.
  • Taylor HS, Vanden Heuvel GB, Igarashi P. A con- served Hox axis in the mouse and human female reproductive system: late establishment and persis- tent adult expression of the Hoxa cluster genes. Biol Reprod 1997;57:1338-45.
  • Taylor HS, Arici A, Olive D, Igarashi P. HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium. J Clin Invest 1998;101:1379-84.
  • Salehnia M. Different pattern of pinopodes expres- sion in stimulated mouse endometrium. Exp Anim 2005;54:349-52.
  • Nikas G. Cell-surface morphological events relevant to human implantation. Hum Reprod 1999;14:37-44.
  • Garcia-Velasco JA, Simon C, Ardiles G. Assessment of endometrial response to HRT using the detection of pinopodes in women with endometriosis under- going oocyte donation. In: 4th Meeting of the American Society of Reproductive Medicine; October 4-9, 1998; San Francisco, California, USA; 1998. p. 242.
  • Taylor HS. The role of HOX genes in human implan- tation. Hum Reprod Update 2000;6:75-9.
  • Taylor HS, Bagot C, Kardana A, Olive D, Arici A. HOX gene expression is altered in the endometrium of women with endometriosis. Hum Reprod 1999; 14:1328-31.
  • Daftary GS, Taylor HS. EMX2 gene expression in the female reproductive tract and aberrant expression in the endometrium of patients with endometriosis. J Clin Endocrinol Metab 2004;89:2390-6.
  • Lessey BA, Damjanovich L, Coutifaris C, Castelbaum A, Albelda SM, Buck CA. Integrin adhe- sion molecules in the human endometrium. Correlation with the normal and abnormal menstru- al cycle. J Clin Invest 1992;90:188-95.
  • Adams EC, Hertig AT, Rock J. A description of 34 human ova within the first 17 days of development. Am J Anat 1956;98:435-93.
  • Navot D, Bergh PA, Williams M, Garrisi GJ, Guzman I, Sandler B, et al. An insight into early reproductive processes through the in vivo model of ovum dona- tion. J Clin Endocrinol Metab 1991;72:408-14.
  • Lessey BA, Castelbaum AJ, Sawin SW, Buck CA, Schinnar R, Bilker W, et al. Aberrant integrin expres- sion in the endometrium of women with endometrio- sis. J Clin Endocrinol Metab 1994;79:643-9.
  • Lessey BA, Young SL. Integrins and other cell adhe- sion molecules in endometrium and endometriosis. Semin Reprod Endocrinol 1997;15:291-9.
  • Cakmak H, Schatz F, Huang ST, Buchwalder L, Rahman M, Arici A, et al. Progestin suppresses thrombin- and interleukin-1beta-induced inter- leukin-11 production in term decidual cells: implica- tions for preterm delivery. J Clin Endocrinol Metab 2005;90:5279-86.
  • Seli E, Kayisli UA, Cakmak H, Bukulmez O, Bildirici I, Guzeloglu-Kayisli O, et al. Removal of hydrosalp- inges increases endometrial leukaemia inhibitory factor (LIF) expression at the time of the implanta- tion window. Hum Reprod 2005;20:3012-7.
  • Bilinski P, Roopenian D, Gossler A. Maternal IL- 11Ralpha function is required for normal decidua and fetoplacental development in mice. Genes Dev 1998;12:2234-43.
  • Robb L, Li R, Hartley L, Nandurkar HH, Koentgen F, Begley CG. Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uter- ine response to implantation. Nat Med 1998;4:303-8.
  • Stewart CL, Kaspar P, Brunet LJ, Bhatt H, Gadi I, Köntgen F, et al. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature 1992;359:76-9.
  • Aghajanova L, Stavreus-Evers A, Nikas Y, Hovatta O, Landgren BM. Coexpression of pinopodes and leukemia inhibitory factor, as well as its receptor, in human endometrium. Fertil Steril 2003;79:808-14.
  • Cork BA, Li TC, Warren MA, Laird SM. Interleukin- 11 (IL-11) in human endometrium: expression throughout the menstrual cycle and the effects of cytokines on endometrial IL-11 production in vitro. J Reprod Immunol 2001;50:3-17.
  • Cullinan EB, Abbondanzo SJ, Anderson PS, Pollard JW, Lessey BA, Stewart CL. Leukemia inhibitory fac- tor (LIF) and LIF receptor expression in human en- dometrium suggests a potential autocrine/paracrine function in regulating embryo implantation. Proc Natl Acad Sci USA 1996;93:3115-20.
  • Dimitriadis E, Stoikos C, Stafford-Bell M, Clark I, Paiva P, Kovacs G, et al. Interleukin-11, IL-11 recep- toralpha and leukemia inhibitory factor are dysreg- ulated in endometrium of infertile women with endometriosis during the implantation window. J Reprod Immunol 2006;69:53-64.
  • Inoue M, Kobayashi Y, Honda I, Awaji H, Fujii A. The impact of endometriosis on the reproductive outcome of infertile patients. Am J Obstet Gynecol 1992;167:278-82.
  • Dmowski WP, Rana N, Michalowska J, Friberg J, Papierniak C, el-Roeiy A. The effect of endometrio- sis, its stage and activity, and of autoantibodies on in vitro fertilization and embryo transfer success rates. Fertil Steril 1995;63:555-62.
  • Olivennes F, Feldberg D, Liu HC, Cohen J, Moy F, Rosenwaks Z. Endometriosis: a stage by stage anal- ysis-the role of in vitro fertilization. Fertil Steril 1995; 64:392-8.
  • Pal L, Shifren JL, Isaacson KB, Chang Y, Leykin L, Toth TL. Impact of varying stages of endometriosis on the outcome of in vitro fertilization-embryo transfer. J Assist Reprod Genet 1998;15:27-31.
  • Bukulmez O, Yarali H, Gurgan T. The presence and extent of endometriosis do not effect clinical preg- nancy and implantation rates in patients undergoing intracytoplasmic sperm injection. Eur J Obstet Gynecol Reprod Biol 2001;96:102-7.
  • Azem F, Lessing JB, Geva E, Shahar A, Lerner-Geva L, Yovel I, et al. Patients with stages III and IV endometriosis have a poorer outcome of in vitro fer- tilization-embryo transfer than patients with tubal infertility. Fertil Steril 1999;72:1107-9.
  • Diaz I, Navarro J, Blasco L, Simon C, Pellicer A, Remohi J. Impact of stage III-IV endometriosis on recipients of sibling oocytes: matched case-control study. Fertil Steril 2000;74:31-4.
  • Remohi J, Ardiles G, Garcia-Velasco JA, Gaitan P, Simon C, Pellicer A. Endometrial thickness and serum oestradiol concentrations as predictors of outcome in oocyte donation. Hum Reprod 1997;12:2271-6.
Toplam 79 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Gülnur Kızılay Bu kişi benim

Gülnur Kızılay Bu kişi benim

Hakan Çakmak Bu kişi benim

Aydın Arıcı Bu kişi benim

Yayımlanma Tarihi 1 Şubat 2007
Yayımlandığı Sayı Yıl 2007 Cilt: 2007 Sayı: 2

Kaynak Göster

APA Kızılay, G., Kızılay, G., Çakmak, H., Arıcı, A. (2007). Endometriosis ve implantasyon. Balkan Medical Journal, 2007(2), 90-97.
AMA Kızılay G, Kızılay G, Çakmak H, Arıcı A. Endometriosis ve implantasyon. Balkan Medical Journal. Şubat 2007;2007(2):90-97.
Chicago Kızılay, Gülnur, Gülnur Kızılay, Hakan Çakmak, ve Aydın Arıcı. “Endometriosis Ve Implantasyon”. Balkan Medical Journal 2007, sy. 2 (Şubat 2007): 90-97.
EndNote Kızılay G, Kızılay G, Çakmak H, Arıcı A (01 Şubat 2007) Endometriosis ve implantasyon. Balkan Medical Journal 2007 2 90–97.
IEEE G. Kızılay, G. Kızılay, H. Çakmak, ve A. Arıcı, “Endometriosis ve implantasyon”, Balkan Medical Journal, c. 2007, sy. 2, ss. 90–97, 2007.
ISNAD Kızılay, Gülnur vd. “Endometriosis Ve Implantasyon”. Balkan Medical Journal 2007/2 (Şubat 2007), 90-97.
JAMA Kızılay G, Kızılay G, Çakmak H, Arıcı A. Endometriosis ve implantasyon. Balkan Medical Journal. 2007;2007:90–97.
MLA Kızılay, Gülnur vd. “Endometriosis Ve Implantasyon”. Balkan Medical Journal, c. 2007, sy. 2, 2007, ss. 90-97.
Vancouver Kızılay G, Kızılay G, Çakmak H, Arıcı A. Endometriosis ve implantasyon. Balkan Medical Journal. 2007;2007(2):90-7.