Mikroalbüminüri: Kardiyovasküler Risk Faktörü

Ertuğrul Ercan

Microalbuminuria: a Cardiovascular Risk Factor

Yıl 2010, Cilt: 2010 Sayı: 1, 42 - 48, 01.01.2010

Öz

Albumin is a protein which is charged negatively. By correcting for the daily excretion of creatinine, the albumin creatinin ratio implicates the daily excretion of albumin in spot urine. Albuminuria is a cardiovascular risk factor in patients with diabetes, hypertension, and the general population. Urinary albumin excretion is independently associated with an increased risk of cardiovascular events, even after adjustment for risk factors. Risk has been shown to increase continuously with increasing urinary albumin levels. Urinary albumin excretion rate should be monitorized routinely in a group of patients with high cardiovascular risk. Albümin negatif yüklü bir proteindir. Albümin kreatinin oranı spot idrarda protein içeriğini değerlendirmek için kullanılır. Albüminüri genel populasyonda hipertansiflerde ve diabetiklerde yüksek risk göstergesidir. Albüminüri ve kardiyovasküler olaylar arasındaki ilişki risk faktörlerinin etkisi dışlanıldıktan sonra dahi devam etmektedir. Risk düzeyi idrar albümin miktarı ile doğru orantılı olarak artış göstermektedir. İdrar albümin atılım hızının takip edilmesi yüksek kardiyovasküler riske sahip olgularda önerilir.

Anahtar Kelimeler

Microalbuminuria, cardiovascular, risk

Kaynakça

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