Melanocytic Nevus of the Tarsal Conjunctiva

Yıl 2016, Cilt: 33 Sayı: 4, 477 - 479, 01.07.2016

Bülent Yazıcı Ayşe Dolar Bilge Ayşe Yağcı Faisal Naqadan Filiz Altıntepe

Öz

Background: Melanocytic nevus is a rare occurrence in the tarsal conjunctiva and only 7 well-described cases have been reported previously in the English literature. Case Report: The medical records of 4 patients with tarsal conjunctival melanocytic nevus were reviewed, together with the relevant literature. All patients (3 women and 1 man; age range: 17 - 40 years) had been referred with a suspicion of melanoma. There was one tarsal nevus in the lower eyelid in 3 patients and 2 nevi in the upper eyelid in 1 patient. All lesions were darkly pigmented with irregular borders and were associated with a history of a recent growth in size. An intralesional cyst was present in 1 nevus only. After surgical excision, no recurrence or complication occurred during the follow-up period (range: 7 - 48 months). Conclusion: Tarsal melanocytic nevus has been described in detail in 11 cases, including these 4 cases, in the English literature. The lesion arose from the lower eyelid in all cases except one. Tarsal melanocytic nevi may frequently display clinical features suggesting melanoma, such as advanced patient age, recent growth, dark and irregular pigmentation, nodularity, hypervascularity, and the absence of an intralesional cyst. After total excision, nevus recurrence or malignant trans-formation has not been reported.

Anahtar Kelimeler

Conjunctiva, conjunctival nevus, melanocytic nevus, tarsal plate

Kaynakça

• 1. Buckman G, Jakobiec FA, Folberg R, McNally LM. Melanocytic nevi of the palpebral conjunctiva: an extremely rare location usually signifying melanoma. Ophthalmology 1988;95:1053-7. [Crossref]
• 2. Obata H, Kubota M, Kawai T, Tsuru T. Nevocellular nevus of the palpebral conjunctiva. Acta Ophthalmol Scand 2004;82:632- 3. [Crossref]
• 3. Gerner N, Nørregaard JC, Jensen OA, Prause JU. Conjunctival naevi in Denmark 1960–1980. A 21-year follow-up study. Acta Ophthalmol Scand 1996;74:334-7. [Crossref]
• 4. Shields CL, Fasiuddin AF, Mashayekhi A, Shields JA. Conjunctival nevi: clinical features and natural course in 410 consecutive patients. Arch Ophthalmol 2004;122:167-75. [Crossref]
• 5. Kim HJ, McCormick SA, Nath S, Moskowitz B, Milman T. Melanocytic nevi of the tarsal conjunctiva: Clinicopathologic case series with review of literature. Ophthal Plast Reconstr Surg 2010;26:438-42. [Crossref]
• 6. Paridaens AD, Minassian DC, McCartney AC, Hungerford JL. Prognostic factors in primary malignant melanoma of the conjunctiva: clinicopathological study of 256 cases. Br J Ophthalmol 1994;78:252-9. [Crossref]
• 7. Shields CL, Markowitz JS, Belinsky I, Schwartzstein H, George NS, Lally SE, et al. Conjunctival melanoma: outcomes based on tumor origin in 382 consecutive cases. Ophthalmology 2011;118:389-95. [Crossref