Yıl 2017,
Cilt: 34 Sayı: 1, 85 - 87, 01.01.2017
Hasan Bozkurt
Serkan Şahin
Kaynakça
- 1. Harmon WJ, Nehra A. Priapism: diagnosis and management. Mayo Clin
Proc 1997;72:350-5.
- 2. Shahani L. Olanzapine-associated priapism. J Neuropsychiatry Clin
Neurosci 2012;24:E28.
- 3. Hosseini SH, Polonowita AK. Priapism associated with olanzapine. Pak J
Biol Sci 2009;12:198-200.
- 4. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al.
A method for estimating the probability of adverse drug reactions. Clin
Pharmacol Ther 1981;30:239-45.
- 5. Jagadheesan K, Thakur A, Akhtar S. Irreversible priapism during
olanzapine and lithium therapy. Aust N Z J Psychiatry 2004;38:381.
- 6. Matthews SC, Dimsadle JE. Priapism after a suicide attempt by ingestion
of olanzapine and gabapentin. Psychosomatics 2001;42:280-1.
- 7. Kuperman JR, Asher I, Modai I. Olanzapine-associated priapism. J Clin
Psychopharmacol 2001;21:247.
- 8. Childers JB, Schwartz AC, Compton MT. Olanzapine-associated priapism.
Psychosomatics 2003;44:351-2.
- 9. Hauri D, Spycher M, Bruhlmann W. Erection and priapism: a new
physiopathological concept. Urol Int 1983;38:138-45.
- 10. Deirmenjian JM, Erhart SM, Wirshing DA, Spellberg BJ, Wirshing
WC. Olanzapine-induced reversible priapism: a case report. J Clin
Psychopharmacol 1998;18:351-3.
Olanzapine-induced Priapism in a Child with Asperger’s Syndrome
Yıl 2017,
Cilt: 34 Sayı: 1, 85 - 87, 01.01.2017
Hasan Bozkurt
Serkan Şahin
Öz
Background: Priapism is a potentially painful and prolonged erection that occurs in the absence of any stimulation. Olanzapine has been reported to induce priapism in several adult cases with schizophrenia and/or mood disorders but very rarely reported in children. Case Report: 9-year-old male with Asperger’s Syndrome (AS) referred to our clinic with the complaints of inattention, hyperactivity and impulsivity. He was diagnosed with attention deficit hyperactivity disorder (ADHD) and given methylphenidate treatment which ameliorated his ADHD symptoms. He started to have severe loss of appetite after methylphenidate treatment so olanzapine 2.5 mg/day was added to cope with severe inappetence. However he experienced priapism after olanzapine and priapism resolved after ceasing the drug. His mother restarted olanzapine because he benefited from olanzapine. But the same episodes occurred soon after olanzapine again and his mother had to stop the medication. Conclusion: Because atypical antipsychotics are now widely used in children, unusual side effects such as priapism should be taken into consideration for the differential diagnosis.
Kaynakça
- 1. Harmon WJ, Nehra A. Priapism: diagnosis and management. Mayo Clin
Proc 1997;72:350-5.
- 2. Shahani L. Olanzapine-associated priapism. J Neuropsychiatry Clin
Neurosci 2012;24:E28.
- 3. Hosseini SH, Polonowita AK. Priapism associated with olanzapine. Pak J
Biol Sci 2009;12:198-200.
- 4. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al.
A method for estimating the probability of adverse drug reactions. Clin
Pharmacol Ther 1981;30:239-45.
- 5. Jagadheesan K, Thakur A, Akhtar S. Irreversible priapism during
olanzapine and lithium therapy. Aust N Z J Psychiatry 2004;38:381.
- 6. Matthews SC, Dimsadle JE. Priapism after a suicide attempt by ingestion
of olanzapine and gabapentin. Psychosomatics 2001;42:280-1.
- 7. Kuperman JR, Asher I, Modai I. Olanzapine-associated priapism. J Clin
Psychopharmacol 2001;21:247.
- 8. Childers JB, Schwartz AC, Compton MT. Olanzapine-associated priapism.
Psychosomatics 2003;44:351-2.
- 9. Hauri D, Spycher M, Bruhlmann W. Erection and priapism: a new
physiopathological concept. Urol Int 1983;38:138-45.
- 10. Deirmenjian JM, Erhart SM, Wirshing DA, Spellberg BJ, Wirshing
WC. Olanzapine-induced reversible priapism: a case report. J Clin
Psychopharmacol 1998;18:351-3.