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The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis

Yıl 2017, Cilt: 34 Sayı: 6, 487 - 492, 01.11.2017

Öz

This paper reviews translational research in psychiatry, focusing on those programs addressing the problem of the validity of psychiatric diagnoses. In medicine in general, and in psychiatry in particular, the term “translational” is used with different meanings. A conceptual analysis suggests that there are at least seven different types of translational research in psychiatry: T1 (“bench-to-bedside” development of tools and treatments), T2 (application of animal models to human psychiatry), T3 (papers focusing on the mind-brain gap, studying biological, neurobiological and cognitive dysfunctions), T4 (personalised therapies and prediction of treatment responses), T5 (“bedside-to-bench” translation of population data for laboratories), T6 (implementation of treatments at the population level, including accessibility and quality of services), and T7 (improving translational knowledge in residents’ trainings and researchers’ careers).Concerning the problem of validity of psychiatric diagnoses, new neurocognitive models like the Research Domain Criteria project are considered, in particular the translational program of cross-validation aimed at reducing the gap between neuroimaging data and psychopathological scores derived from rating-scales. It is shown that these programs are useful, filling some of the current research gaps, but it is also stressed that they carry implicit realist and reductionist assumptions. It is finally suggested that the formation of mental symptoms is a complex process involving both neurocognitive and semantic factors, which raises doubts about the possibility of complete translations, without residuals.

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Ayrıntılar

Diğer ID JA99ZE36FG
Bölüm Araştırma Makalesi
Yazarlar

Massimiliano Aragona Bu kişi benim

Yayımlanma Tarihi 1 Kasım 2017
Yayımlandığı Sayı Yıl 2017 Cilt: 34 Sayı: 6

Kaynak Göster

APA Aragona, M. (2017). The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis. Balkan Medical Journal, 34(6), 487-492.
AMA Aragona M. The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis. Balkan Medical Journal. Kasım 2017;34(6):487-492.
Chicago Aragona, Massimiliano. “The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis”. Balkan Medical Journal 34, sy. 6 (Kasım 2017): 487-92.
EndNote Aragona M (01 Kasım 2017) The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis. Balkan Medical Journal 34 6 487–492.
IEEE M. Aragona, “The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis”, Balkan Medical Journal, c. 34, sy. 6, ss. 487–492, 2017.
ISNAD Aragona, Massimiliano. “The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis”. Balkan Medical Journal 34/6 (Kasım 2017), 487-492.
JAMA Aragona M. The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis. Balkan Medical Journal. 2017;34:487–492.
MLA Aragona, Massimiliano. “The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis”. Balkan Medical Journal, c. 34, sy. 6, 2017, ss. 487-92.
Vancouver Aragona M. The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis. Balkan Medical Journal. 2017;34(6):487-92.