Derleme
BibTex RIS Kaynak Göster

Kimyasal Maddelerin Savaşı: Boğucu Gazlar

Yıl 2025, Cilt: 8 Sayı: 1, 1 - 12, 30.06.2025

Öz

Boğucu gazlar kişiyi esas olarak solunum sistemi üzerinde etkileyen, endüstri alanında kullanılması nedeniyle terör grupları tarafından kolay elde edilen ve kontrolü oldukça zor olan, büyük miktarlarda üretilen kimyasal savaş ajanlarıdır. Birinci Dünya Savaşı sırasından bu yana kullanılmaya başlanan ve kullanımıyla ağır zaiyatlara sebep olan boğucu kimyasal savaş ajanları ne yazık ki günümüzde de hala varlığını sürdürmekte ve bir savaş aracı olarak kullanılmaya devam etmektedir. KBRN olaylarında hastane öncesi alanda görev alan bütün çalışanlar tarafından başlıca boğucu gazların neler oldukları, fiziksel ve kimyasal özellikleri, toksisite mekanizmalarının bilinmesi; kullanımının önüne geçemediğimiz bu gazların etkilerinin hafifletilmesinde yardımcı olacaktır. Boğucu gazların antidotu olmamakla birlikte kortikoid kullanımı önerilmektedir. Tedavi bronkodilatörler, yüksek doz kortikosteroidler ve profilaktik antibiyotiklerle solunum desteği içermektedir. Tedavi semptomlara dayalı uygulanmaktadır. Boğucu gazlara maruziyet durumunda yeni tedavi yöntemleri ve antidot çalışmaları geliştirilmelidir.

Kaynakça

  • Allegaert, K., van den Anker, J. N. (2015). Adverse drug reactions in neonates and infants: a population-tailored approach is needed. Br J Clin Pharmacol, 80(4), 788-795.
  • Arpaci, T., Toruner, E. K., Altay, N. (2018). Assessment of Nutritional Problems in Pediatric Patients with Cancer and the Information Needs of Their Parents: A Parental Perspective. Asia Pac J Oncol Nurs, 5(2), 231-236.
  • Ayşegül, T., Avci, A. (2011). Metabolic and Endocrine Side Effects of Atypical Antipsychotic Drugs in Children and Adolescents. Psikiyatride Guncel Yaklasimlar, 3.
  • Bacharier, L. B., Boner, A., Carlsen, K. H., Eigenmann, P. A., Frischer, T., Götz, M., Wildhaber, J. (2008). Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report. Allergy, 63(1), 5-34.
  • Cook, R. C., Blinman, T. A. (2010). Nutritional support of the pediatric trauma patient. Semin Pediatr Surg, 19(4), 242-251.
  • Corkins, M. R., Griggs, K. C., Groh-Wargo, S., Han-Markey, T. L., Helms, R. A., Muir, L. V., Szeszycki, E. E. (2013). Standards for nutrition support: pediatric hospitalized patients. Nutr Clin Pract, 28(2), 263-276.
  • Costi, S., Giani, T., Orsini, F., Cimaz, R. (2022). Drug Treatment of Low Bone Mass and Other Bone Conditions in Pediatric Patients. Paediatr Drugs, 24(2), 103-119.
  • Ekvall, S., Ekvall, R. (2005). Pediatric Nutrition In Chronic Diseases And Developmental Disorders: Prevention, Assessment, And Treatment.
  • Heidari, H., Mohammadbeigi, A., Soltanzadeh, A., Darabi, M., Asadi-Ghalhari, M. (2019). Respiratory effects of occupational exposure to low concentration of hydrochloric acid among exposed workers: a case study in steel industry. Med Gas Res, 9(4), 208-212.
  • Hughes, E. (2017). Nutritional Protocol for Asthma. Journal of Nutrition and Dietetics, 3.
  • Kleinman, R. E., Baldassano, R. N., Caplan, A., Griffiths, A. M., Heyman, M. B., Issenman, R. M., Udall, J. N. (2004). Nutrition support for pediatric patients with inflammatory bowel disease: a clinical report of the North American Society for Pediatric Gastroenterology, Hepatology And Nutrition. J Pediatr Gastroenterol Nutr, 39(1), 15-27.
  • McCloud, E., Papoutsakis, C. (2011). A medical nutrition therapy primer for childhood asthma: current and emerging perspectives. J Am Diet Assoc, 111(7), 1052-1064.
  • Papoutsakis, C., Priftis, K. N., Drakouli, M., Prifti, S., Konstantaki, E., Chondronikola, M., Matziou, V. (2013). Childhood overweight/obesity and asthma: is there a link? A systematic review of recent epidemiologic evidence. J Acad Nutr Diet, 113(1), 77-105.
  • Pesonen, M., Vähäkangas, K. (2020). Chloropicrin-induced toxicity in the respiratory system. Toxicol Lett, 323, 10-18.
  • Petersson, K. J., Hanze, E., Savic, R. M., Karlsson, M. O. (2009). Semiparametric distributions with estimated shape parameters. Pharm Res, 26(9), 2174-2185.
  • Pitschmann, V., Hon, Z. (2023). Drugs as Chemical Weapons: Past and Perspectives. Toxics, 11(1).
  • Sanghera, N., Chan, P. Y., Khaki, Z. F., Planner, C., Lee, K. K., Cranswick, N. E., Wong, I. C. (2006). Interventions of hospital pharmacists in improving drug therapy in children: a systematic literature review. Drug Saf, 29(11), 1031-1047.
  • Tripodi, S. I., Bergami, E., Panigari, A., Caissutti, V., Brovia, C., De Cicco, M., Zecca, M. (2023). The role of nutrition in children with cancer. Tumori, 109(1), 19-27.
  • Ty, S. H., Sudha Ty, D. S., Sasanka, K. K., Nageswar Rao, K., T, P. (2023). Accidental Phosgene Poisoning: A Case Report and Short Review of Management. Cureus, 15(7), e41679.
  • Veiby, G., Engelsen, B. A., Gilhus, N. E. (2013). Early child development and exposure to antiepileptic drugs prenatally and through breastfeeding: a prospective cohort study on children of women with epilepsy. JAMA Neurol, 70(11), 1367-1374.
  • Williams, M., Armstrong, L., Sizemore, D. C. (2024). Biologic, Chemical, and Radiation Terrorism Review. In StatPearls. Treasure Island (FL) ineligible companies.

WAR OF CHEMİCAL AGENTS: CHOKİNG GASES

Yıl 2025, Cilt: 8 Sayı: 1, 1 - 12, 30.06.2025

Öz

Choking gases are chemical warfare agents produced in large quantities that affect the person mainly on the respiratory system, are easily obtained by terrorist groups due to their use in industry, and are very difficult to control. Choking chemical warfare agents, which have been used since the First World War and caused heavy casualties, unfortunately still exist today and continue to be used as a tool of war. In CBRN incidents, all employees working in the pre-hospital area should know what the main choking gases are, their physical and chemical properties, and their toxicity mechanisms; It will help alleviate the effects of these gases, the use of which we cannot prevent. Although there is no antidote for choking gases, the use of corticoids is recommended. Treatment includes respiratory support with bronchodilators, high-dose corticosteroids, and prophylactic antibiotics. Treatment is applied based on symptoms. In case of exposure to choking gases, new treatment methods and antidote studies should be developed.

Kaynakça

  • Allegaert, K., van den Anker, J. N. (2015). Adverse drug reactions in neonates and infants: a population-tailored approach is needed. Br J Clin Pharmacol, 80(4), 788-795.
  • Arpaci, T., Toruner, E. K., Altay, N. (2018). Assessment of Nutritional Problems in Pediatric Patients with Cancer and the Information Needs of Their Parents: A Parental Perspective. Asia Pac J Oncol Nurs, 5(2), 231-236.
  • Ayşegül, T., Avci, A. (2011). Metabolic and Endocrine Side Effects of Atypical Antipsychotic Drugs in Children and Adolescents. Psikiyatride Guncel Yaklasimlar, 3.
  • Bacharier, L. B., Boner, A., Carlsen, K. H., Eigenmann, P. A., Frischer, T., Götz, M., Wildhaber, J. (2008). Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report. Allergy, 63(1), 5-34.
  • Cook, R. C., Blinman, T. A. (2010). Nutritional support of the pediatric trauma patient. Semin Pediatr Surg, 19(4), 242-251.
  • Corkins, M. R., Griggs, K. C., Groh-Wargo, S., Han-Markey, T. L., Helms, R. A., Muir, L. V., Szeszycki, E. E. (2013). Standards for nutrition support: pediatric hospitalized patients. Nutr Clin Pract, 28(2), 263-276.
  • Costi, S., Giani, T., Orsini, F., Cimaz, R. (2022). Drug Treatment of Low Bone Mass and Other Bone Conditions in Pediatric Patients. Paediatr Drugs, 24(2), 103-119.
  • Ekvall, S., Ekvall, R. (2005). Pediatric Nutrition In Chronic Diseases And Developmental Disorders: Prevention, Assessment, And Treatment.
  • Heidari, H., Mohammadbeigi, A., Soltanzadeh, A., Darabi, M., Asadi-Ghalhari, M. (2019). Respiratory effects of occupational exposure to low concentration of hydrochloric acid among exposed workers: a case study in steel industry. Med Gas Res, 9(4), 208-212.
  • Hughes, E. (2017). Nutritional Protocol for Asthma. Journal of Nutrition and Dietetics, 3.
  • Kleinman, R. E., Baldassano, R. N., Caplan, A., Griffiths, A. M., Heyman, M. B., Issenman, R. M., Udall, J. N. (2004). Nutrition support for pediatric patients with inflammatory bowel disease: a clinical report of the North American Society for Pediatric Gastroenterology, Hepatology And Nutrition. J Pediatr Gastroenterol Nutr, 39(1), 15-27.
  • McCloud, E., Papoutsakis, C. (2011). A medical nutrition therapy primer for childhood asthma: current and emerging perspectives. J Am Diet Assoc, 111(7), 1052-1064.
  • Papoutsakis, C., Priftis, K. N., Drakouli, M., Prifti, S., Konstantaki, E., Chondronikola, M., Matziou, V. (2013). Childhood overweight/obesity and asthma: is there a link? A systematic review of recent epidemiologic evidence. J Acad Nutr Diet, 113(1), 77-105.
  • Pesonen, M., Vähäkangas, K. (2020). Chloropicrin-induced toxicity in the respiratory system. Toxicol Lett, 323, 10-18.
  • Petersson, K. J., Hanze, E., Savic, R. M., Karlsson, M. O. (2009). Semiparametric distributions with estimated shape parameters. Pharm Res, 26(9), 2174-2185.
  • Pitschmann, V., Hon, Z. (2023). Drugs as Chemical Weapons: Past and Perspectives. Toxics, 11(1).
  • Sanghera, N., Chan, P. Y., Khaki, Z. F., Planner, C., Lee, K. K., Cranswick, N. E., Wong, I. C. (2006). Interventions of hospital pharmacists in improving drug therapy in children: a systematic literature review. Drug Saf, 29(11), 1031-1047.
  • Tripodi, S. I., Bergami, E., Panigari, A., Caissutti, V., Brovia, C., De Cicco, M., Zecca, M. (2023). The role of nutrition in children with cancer. Tumori, 109(1), 19-27.
  • Ty, S. H., Sudha Ty, D. S., Sasanka, K. K., Nageswar Rao, K., T, P. (2023). Accidental Phosgene Poisoning: A Case Report and Short Review of Management. Cureus, 15(7), e41679.
  • Veiby, G., Engelsen, B. A., Gilhus, N. E. (2013). Early child development and exposure to antiepileptic drugs prenatally and through breastfeeding: a prospective cohort study on children of women with epilepsy. JAMA Neurol, 70(11), 1367-1374.
  • Williams, M., Armstrong, L., Sizemore, D. C. (2024). Biologic, Chemical, and Radiation Terrorism Review. In StatPearls. Treasure Island (FL) ineligible companies.
Toplam 21 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Politikası, Politika ve Yönetim (Diğer)
Bölüm Derleme
Yazarlar

Elif Demirbaş 0000-0003-3326-4822

Beyza Armağan 0009-0001-2584-9989

Sude Yamaç 0009-0008-6356-8564

Murat Ihlamur 0000-0002-0458-5638

Yayımlanma Tarihi 30 Haziran 2025
Gönderilme Tarihi 11 Mayıs 2024
Kabul Tarihi 31 Mayıs 2024
Yayımlandığı Sayı Yıl 2025 Cilt: 8 Sayı: 1

Kaynak Göster

APA Demirbaş, E., Armağan, B., Yamaç, S., Ihlamur, M. (2025). WAR OF CHEMİCAL AGENTS: CHOKİNG GASES. Biruni Sağlık ve Eğitim Bilimleri Dergisi, 8(1), 1-12.