Determination of the Antimicrobial Potential of Naturally Grown Rosehip (Rosa canina L.) Fruit in the Giresun Region

Öz

The rise of antibiotic-resistant microorganisms has become a major global public health challenge, prompting the search for alternative antimicrobial agents. In this study, the antimicrobial activity of Rosa canina (rosehip) fruit extract, collected from the Alucra Plateau in Giresun, Türkiye, was evaluated under in vitro conditions. Methanolic extracts were tested against Gram-positive (Bacillus subtilis, Staphylococcus aureus) and Gram-negative (Escherichia coli, Enterobacter aerogenes) bacteria, as well as fungal strains (Candida albicans, Candida glabrata, Candida tropicalis) using the disk diffusion method. At a concentration of 30 mg/mL, the extract demonstrated significant inhibition zones against both bacterial and fungal pathogens. The most notable antifungal effects were observed against C. glabrata (20 mm) and C. tropicalis (16 mm). The absence of antimicrobial activity in the 25% DMSO control confirmed that the effects were solely attributable to the plant extract. These findings suggest that R. canina possesses promising natural antimicrobial properties and could serve as a complementary treatment option, particularly against multidrug-resistant pathogens.

Anahtar Kelimeler

• Rosa canina
• Antimicrobial activity
• Natural extract
• Candida
• Antibacterial effect

Kaynakça

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