Introduction:
Subclinical hyperthyroidsm is associated with negative effects on
cardiovascular system. We aimed to evaluate the association between
pre-operative thyroid hormones and post-operative outcome in patients
undergoing coronary artery by-pass graft (CABG) surgery.
Methods:
A hundred and eighty nine patients with isolated CABG surgery were
included into the study. Patient’s clinical characteristics,
surgical details and post-operative mortality and morbidities were
recorded.Patients were divided into two groups according to their TSH
level with cut-off point of 0,35 was assumed.
Results:
The first group consists of 16 patients (9%) with subclinical
hyperthyroid (SH) and the second group includes 173 euthyroid
patients. In post-operative period; the incidence of arrhythmia,
renal failure and inotropy requirement were significantly higher in
SH group (p<.0001, p: 0.0002 and p<.0001 respectively)
The incidence of
peri-operative mortality was similar between groups. (p: 0.0860).
Lenght of stay in
intesive care unit and overall were significantly higher in patients
with SH (p:
0.0102
and p: 0.0004 respectively).
Discussion and
Conclusion:
Pre-operative subclinical hyperthyroidsm didn’t effect
peri-operative mortality but may lead to higher postoperative
complications such as arrhythmia, renal failure and low cardiacoutput
syndrome in patients undergoing CABG surgery.
subclinical hyperthroidism cardio-vascular disease coronary artery by-pass
Introduction:
Subclinical hyperthyroidsm is associated with negative effects on
cardiovascular system. We aimed to evaluate the association between
pre-operative thyroid hormones and post-operative outcome in patients
undergoing coronary artery by-pass graft (CABG) surgery.
Methods:
A hundred and eighty nine patients with isolated CABG surgery were
included into the study. Patient’s clinical characteristics,
surgical details and post-operative mortality and morbidities were
recorded.Patients were divided into two groups according to their TSH
level with cut-off point of 0,35 was assumed.
Results:
The first group consists of 16 patients (9%) with subclinical
hyperthyroid (SH) and the second group includes 173 euthyroid
patients. In post-operative period; the incidence of arrhythmia,
renal failure and inotropy requirement were significantly higher in
SH group (p<.0001, p: 0.0002 and p<.0001 respectively)
The incidence of
peri-operative mortality was similar between groups. (p: 0.0860).
Lenght of stay in
intesive care unit and overall were significantly higher in patients
with SH (p:
0.0102
and p: 0.0004 respectively).
Discussion and
Conclusion:
Pre-operative subclinical hyperthyroidsm didn’t effect
peri-operative mortality but may lead to higher postoperative
complications such as arrhythmia, renal failure and low cardiacoutput
syndrome in patients undergoing CABG surgery.
subclinical hyperthroidism cardio-vascular disease coronary artery by-pass
Birincil Dil | İngilizce |
---|---|
Bölüm | Araştırma Makalesi |
Yazarlar | |
Yayımlanma Tarihi | 28 Eylül 2018 |
Yayımlandığı Sayı | Yıl 2018 Cilt: 5 Sayı: 3 |