Araştırma Makalesi
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Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery

Yıl 2018, Cilt: 5 Sayı: 3, 80 - 83, 28.09.2018

Öz


Introduction:
Subclinical hyperthyroidsm is associated with negative effects on
cardiovascular system. We aimed to evaluate the association between
pre-operative thyroid hormones and post-operative outcome in patients
undergoing coronary artery by-pass graft (CABG) surgery.


Methods:
A hundred and eighty nine patients with isolated CABG surgery were
included into the study. Patient’s clinical characteristics,
surgical details and post-operative mortality and morbidities were
recorded.Patients were divided into two groups according to their TSH
level with cut-off point of 0,35 was assumed.


Results:
The first group consists of 16 patients (9%) with subclinical
hyperthyroid (SH) and the second group includes 173 euthyroid
patients. In post-operative period; the incidence of arrhythmia,
renal failure and inotropy requirement were significantly higher in
SH group (p<.0001, p: 0.0002 and p<.0001 respectively)


The incidence of
peri-operative mortality was similar between groups. (p: 0.0860).


Lenght of stay in
intesive care unit and overall were significantly higher in patients
with SH (p:

0.0102
and p: 0.0004 respectively).







Discussion and
Conclusion:

Pre-operative subclinical hyperthyroidsm didn’t effect
peri-operative mortality but may lead to higher postoperative
complications such as arrhythmia, renal failure and low cardiacoutput
syndrome in patients undergoing CABG surgery.

Kaynakça

  • Referans1- Parle JV, Maisonneuve P, Sheppard MC, Boyle P, Franklyn JA. Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study. Lancet. 2001; 358(9285):861–865.Referans 2-Iervasi G Pingitore A, Landi P, Racitii M, Ripoli A, Scariattini M, L’Abbate A, Donato L.Low-T3 syndrome:a strong progostic predictor of death in patients with herat disease. Circulation. 2003, 11;107(5):708–13. Referans 3- Biondi B, Cooper DS. The clinical significance of subclinical thyroid dysfunction. Endocr Rev. 2008; 29(1):76–131Referans 4-Park, Y.J., Yoon, J.W., Kim, K.I. et al. Subclinical hypothyroidism might increase the risk of transient atrial fibrillation after coronary artery bypass grafting. Ann Thorac Surg. 2009; 87: 1846–1852Referans 5- Surks MI, Ortiz E, Daniels GH, et al. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA. 2004; 291(2):228–238.Referans 6- Parle JV, Maisonneuve P, Sheppard MC, Boyle P, Franklyn JA. Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study. Lancet. 2001; 358(9285):861–865.Referans 7- Sawin CT, Geller A, Wolf PA, et al. Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med. 1994; 331(19):1249–1252.Referans 8- Kaptein EM. Thyroid function in renal failure. Contrib Nephrol. 1986;50:64–72Referans 9- Klein I, Ojamaa K. Thyroid hormone and the cardiovascular system. N Engl J Med. 2001. February 15; 344 7: 501– 9Referans 10-Chu SH, Huang TS, Wang SS, Wang CJ. Thyroid hormon changes after cardiovascular surgery and clinical implications. Ann Thorac Surg 1991;52:791-6

Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery

Yıl 2018, Cilt: 5 Sayı: 3, 80 - 83, 28.09.2018

Öz


Introduction:
Subclinical hyperthyroidsm is associated with negative effects on
cardiovascular system. We aimed to evaluate the association between
pre-operative thyroid hormones and post-operative outcome in patients
undergoing coronary artery by-pass graft (CABG) surgery.


Methods:
A hundred and eighty nine patients with isolated CABG surgery were
included into the study. Patient’s clinical characteristics,
surgical details and post-operative mortality and morbidities were
recorded.Patients were divided into two groups according to their TSH
level with cut-off point of 0,35 was assumed.


Results:
The first group consists of 16 patients (9%) with subclinical
hyperthyroid (SH) and the second group includes 173 euthyroid
patients. In post-operative period; the incidence of arrhythmia,
renal failure and inotropy requirement were significantly higher in
SH group (p<.0001, p: 0.0002 and p<.0001 respectively)


The incidence of
peri-operative mortality was similar between groups. (p: 0.0860).


Lenght of stay in
intesive care unit and overall were significantly higher in patients
with SH (p:

0.0102
and p: 0.0004 respectively).







Discussion and
Conclusion:

Pre-operative subclinical hyperthyroidsm didn’t effect
peri-operative mortality but may lead to higher postoperative
complications such as arrhythmia, renal failure and low cardiacoutput
syndrome in patients undergoing CABG surgery.

Kaynakça

  • Referans1- Parle JV, Maisonneuve P, Sheppard MC, Boyle P, Franklyn JA. Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study. Lancet. 2001; 358(9285):861–865.Referans 2-Iervasi G Pingitore A, Landi P, Racitii M, Ripoli A, Scariattini M, L’Abbate A, Donato L.Low-T3 syndrome:a strong progostic predictor of death in patients with herat disease. Circulation. 2003, 11;107(5):708–13. Referans 3- Biondi B, Cooper DS. The clinical significance of subclinical thyroid dysfunction. Endocr Rev. 2008; 29(1):76–131Referans 4-Park, Y.J., Yoon, J.W., Kim, K.I. et al. Subclinical hypothyroidism might increase the risk of transient atrial fibrillation after coronary artery bypass grafting. Ann Thorac Surg. 2009; 87: 1846–1852Referans 5- Surks MI, Ortiz E, Daniels GH, et al. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA. 2004; 291(2):228–238.Referans 6- Parle JV, Maisonneuve P, Sheppard MC, Boyle P, Franklyn JA. Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study. Lancet. 2001; 358(9285):861–865.Referans 7- Sawin CT, Geller A, Wolf PA, et al. Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med. 1994; 331(19):1249–1252.Referans 8- Kaptein EM. Thyroid function in renal failure. Contrib Nephrol. 1986;50:64–72Referans 9- Klein I, Ojamaa K. Thyroid hormone and the cardiovascular system. N Engl J Med. 2001. February 15; 344 7: 501– 9Referans 10-Chu SH, Huang TS, Wang SS, Wang CJ. Thyroid hormon changes after cardiovascular surgery and clinical implications. Ann Thorac Surg 1991;52:791-6
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makalesi
Yazarlar

Eyüp Avcı

Ahmet Dolapoğlu

Muhammed Kızılgül Bu kişi benim

Yayımlanma Tarihi 28 Eylül 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 5 Sayı: 3

Kaynak Göster

APA Avcı, E., Dolapoğlu, A., & Kızılgül, M. (2018). Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 5(3), 80-83.
AMA Avcı E, Dolapoğlu A, Kızılgül M. Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery. CBU-SBED. Eylül 2018;5(3):80-83.
Chicago Avcı, Eyüp, Ahmet Dolapoğlu, ve Muhammed Kızılgül. “Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 5, sy. 3 (Eylül 2018): 80-83.
EndNote Avcı E, Dolapoğlu A, Kızılgül M (01 Eylül 2018) Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 5 3 80–83.
IEEE E. Avcı, A. Dolapoğlu, ve M. Kızılgül, “Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery”, CBU-SBED, c. 5, sy. 3, ss. 80–83, 2018.
ISNAD Avcı, Eyüp vd. “Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 5/3 (Eylül 2018), 80-83.
JAMA Avcı E, Dolapoğlu A, Kızılgül M. Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery. CBU-SBED. 2018;5:80–83.
MLA Avcı, Eyüp vd. “Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, c. 5, sy. 3, 2018, ss. 80-83.
Vancouver Avcı E, Dolapoğlu A, Kızılgül M. Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery. CBU-SBED. 2018;5(3):80-3.