A rare cause of fever of unknown origin : Autoimmune hepatitis

Yıl 2024, Cilt: 1 Sayı: 2, 144 - 148, 14.06.2024

Emrullah Ataş Sinan Çetin Ahmet Melih Şahin Feyza Yıldız Aytekin İlknur Şenel Emsal Aydın Meltem Arzu Yetkin Esma Çınar

Öz

Fever of unknown origin is difficult to diagnose, and it is seen in the course of infection, malignancy, inflammatory diseases and many other diseases. In this report, a case who presented with fever of unknown origin and was diagnosed with autoimmune hepatitis progressed to acute liver failure is presented. Our case showed a rapid and progressive clinical course, and liver biopsy performed in the early period was useful in the diagnosis. However, mortality developed on the fifteenth day of follow up.

Anahtar Kelimeler

Biopsy, fever of unknown origin, autoimmune hepatitis

Kaynakça

• Petersdorf RG, Beeson PB. Fever of unexplained origin: report on 100 cases. Medicine (Baltimore). 1961;40:1-30. doi:10.1097/00005792-196102000-00001
• Durack DT, Street AC. Fever of unknown origin--reexamined and redefined. Curr Clin Top Infect Dis. 1991;11:35-51.
• Akbayır N. Otoimmün hepatit. Maltepe Tıp Dergisi. 2019;11:55-67.
• Mourad O, Palda V, Detsky AS. A comprehensive evidencebased approach to fever of unknown origin. Arch Intern Med. 2003;163(5):545-551. doi:10.1001/archinte.163.5.545
• Yenilmez E, Kakalicoglu D, Bozkurt F, et al. Fever of unknown origin (FUO) on a land on cross-roads between Asia and Europa; a multicentre study from Turkey. Int J Clin Pract. 2021;75(6):e14138. doi:10.1111/ijcp.14138
• Mitchell DP, Hanes TE, Hoyumpa AM Jr, Schenker S. Fever of unknown origin. Assessment of the value of percutaneous liver biopsy. Arch Intern Med. 1977;137(8):1001-1004.
• Holtz T, Moseley RH, Scheiman JM. Liver biopsy in fever of unknown origin. A reappraisal. J Clin Gastroenterol. 1993;17(1):29-32. doi:10.1097/00004836-199307000-00009
• Czaja AJ. Challenges in the diagnosis and management of autoimmune hepatitis. Can J Gastroenterol. 2013;27(9):531-539. doi:10.1155/2013/981086
• Yasui S, Fujiwara K, Yonemitsu Y, Oda S, Nakano M, Yokosuka O. Clinicopathological features of severe and fulminant forms of autoimmune hepatitis. J Gastroenterol. 2011;46(3):378-390. doi:10.1007/s00535-010-0316-3
• Fujiwara K, Fukuda Y, Yokosuka O. Precise histological evaluation of liver biopsy specimen is indispensable for diagnosis and treatment of acute-onset autoimmune hepatitis. J Gastroenterol. 2008;43(12):951-958. doi:10.1007/s00535-008-2254-x
• Urzúa Á, Pizarro C, Gajardo A, et al. Autoimmune Hepatitis with Acute Presentation: Clinical, Biochemical, and Histological Features of 126 Patients. Can J Gastroenterol Hepatol. 2022;2022:6470847. doi:10.1155/2022/6470847