Evde Sağlık Hizmeti Alan Bireylerde Serum Albümin ve Üriner İnkontinans İlişkisi; Tek Merkez Deneyimi

Yıl 2025, Cilt: 2 Sayı: 3, 153 - 158, 28.10.2025

Arzu Ayraler , İbrahim Onur Köse , Ali İhsan Polat , Neslişah Gürel Köksal , Bekir Bulut

https://doi.org/10.70058/cjm.1681523

Öz

Amaç: Bu çalışma, evde sağlık hizmeti (ESH) alan yaşlı bireylerde serum albümin düzeyleri ile üriner inkontinans (Üİ) arasındaki ilişkiyi değerlendirmeyi amaçlamıştır.

Yöntemler: Giresun Eğitim ve Araştırma Hastanesi EBH biriminde 15 Nisan-15 Mayıs 2024 tarihleri arasında takip edilen, Üİ tanılı 49 hasta ile yaş ve cinsiyet uyumlu 53 Üİ olmayan kontrol hastasının verileri retrospektif olarak analiz edildi. Demografik ve laboratuvar verileri elektronik sağlık kayıtlarından elde edildi. Sürekli değişkenler ortalama ± standart sapma (SS), kategorik değişkenler frekans ve yüzde olarak ifade edildi. Grup karşılaştırmalarında kategorik değişkenler için Ki-kare veya Fisher kesin testi, sürekli değişkenler için bağımsız t-testi kullanıldı. p<0.05 istatistiksel olarak anlamlı kabul edildi.

Bulgular: Kohortun yaş ortalaması 80.6 ± 13.0 yıl olup %68.6'sı kadındı. Üİ ve kontrol grupları arasında serum albümin düzeylerinde anlamlı fark gözlenmedi (37.1 ± 6.8 g/L vs 37.6 ± 5.1 g/L; p = 0.687). Ancak Üİ grubunda serum T4 düzeyleri anlamlı derecede düşüktü (1.2 ± 0.2 μg/dL vs 1.4 ± 0.4 μg/dL; p = 0.001). Diğer laboratuvar parametreleri gruplar arasında farklılık göstermedi.

Sonuç: Bu yaşlı evde bakım popülasyonunda serum albümin düzeyleri ile Üİ arasında anlamlı bir ilişki saptanmamıştır. Ancak T4 düzeylerindeki belirgin fark, tiroid disfonksiyonunun Üİ patofizyolojisinde rolü olabileceğini düşündürmektedir. Bu bulguların doğrulanması için daha geniş örneklemli prospektif çalışmalara ihtiyaç vardır.

Anahtar Kelimeler

Evde sağlık hizmetleri , Albumin , inkontinas

The Relationship Between Serum Albumin and Urinary Incontinence in Home Healthcare Patients: A Single-Center Experience

Öz

Objective: This study aimed to evaluate the association between serum albumin levels and urinary incontinence (UI) in elderly individuals receiving home care services (HCS).
Methods: A retrospective analysis was conducted using data from 49 patients diagnosed with UI and 53 age- and sex-matched controls without UI, who received care at Giresun Training and Research Hospital’s HCS between April 15 and May 15, 2024. Demographic and laboratory data were extracted from electronic health records. Continuous variables were expressed as mean ± standard deviation (SD), and categorical variables as frequencies and percentages. Group comparisons were performed using the Chi-square or Fisher’s exact test for categorical variables, and independent t-tests for continuous variables. A p-value of <0.05 was considered statistically significant.
Results: The mean age of the cohort was 80.6 ± 13.0 years, and 68.6% were female. No significant difference was observed in serum albumin levels between the UI and control groups (37.1 ± 6.8 g/L vs 37.6 ± 5.1 g/L; p = 0.687). However, serum T4 levels were significantly lower in the UI group (1.2 ± 0.2 μg/dL vs 1.4 ± 0.4 μg/dL; p = 0.001). Other laboratory parameters did not differ significantly between groups.
Conclusion: Serum albumin levels were not significantly associated with UI in this elderly home care population. However, the significant difference in T4 levels suggests a potential role of thyroid dysfunction in UI pathophysiology. Prospective studies with larger sample sizes are warranted to validate these findings.

Anahtar Kelimeler

Home Care Services , Albumine , urinary İncontinence

Kaynakça

• Olagundoye O, Odusanya B, Kung JY, Gibson W, Wagg A. A scoping review of risk factors for urinary incontinence in older men. BMC Geriatr. 2023;23(1):534. Published 2023 Sep 2. doi:10.1186/s12877-023-04249-7
• Duralde ER, Walter LC, Van Den Eeden SK, Nakagawa S, Subak LL, Brown JS, et al. Bridging the gap: determinants of undiagnosed or untreated urinary incontinence in women. Am J Obstet Gynecol. 2021;224(6):598.e1–598.e11.
• Nicholson JP, Wolmarans MR, Park GR. The role of albumin in critical illness. Br J Anaesth. 2000;85(4):599–610.
• Yılmaz Oral D, Güven Ciloğlu B, Gür S. The impact of levothyroxine and testosterone administration on bladder contractility in the rat model of propylthiouracil-induced hypothyroidism. Urol Res Pract. 2025;50(4):247–52. doi:10.5152/tud.2025.24099
• Løwenstein E, Jepsen R, Andersen LL, et al. Hypothyroidism and urinary incontinence: Prevalence and association in a Danish, female sample from the Lolland-Falster Health study. Eur J Obstet Gynecol Reprod Biol. 2021;264:232-240. doi:10.1016/j.ejogrb.2021.07.020
• Oral DO, Ciloğlu BG, Gür S. Bladder contractility and hormonal interplay: insights from a hypothyroidism model. Urol Res Pract. 2025;50(4):253–9.
• Neira-Maldonado C, Coronado JC, Álvarez MA, Negrón R, Ponce-Fuentes F, Cuyul-Vásquez I. Prevalence and Associated Factors of Urinary Incontinence Among Chilean Community-Dwelling Older Adults: A Cross-Sectional Study. Cureus. 2025;17(1):e77831. Published 2025 Jan 22. doi:10.7759/cureus.77831
• Batmani S, Jalali R, Mohammadi M, Bokaee S. Prevalence and factors related to urinary incontinence in older adults women worldwide: a comprehensive systematic review and meta-analysis of observational studies [published correction appears in BMC Geriatr. 2022 May 25;22(1):454. doi: 10.1186/s12877-022-03111-6.]. BMC Geriatr. 2021;21(1):212. Published 2021 Mar 29. doi:10.1186/s12877-021-02135-8
• Adani AA, Siyad MO, Adan AM, Jeele MOO. Prevalence and Determinants of Hypothyroidism in Patients on Routine Hemodialysis in Somalia: A Cross-Sectional Study. Int J Gen Med. 2023;16:905-913. Published 2023 Mar 9. doi:10.2147/IJGM.S403950
• Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007;39(2):175-191. doi:10.3758/bf03193146
• Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed. Hillsdale, NJ: Lawrence Erlbaum; 1988.
• Lakens D. Calculating and reporting effect sizes to facilitate cumulative science: A practical primer for t-tests and ANOVAs. Front Psychol. 2013;4:863. doi:10.3389/fpsyg.2013.00863.
• Xu, M., Zhou, H., Pan, Y., Xu, Z., & Liu, X. (2023). Serum albumin levels and stress urinary incontinence in females: A retrospective study based on NHANES 2007-2016. Heliyon, 9(11), e21757. https://doi.org/10.1016/j.heliyon.2023.e21757
• Can B, Can O. The Relationship Between Hypothyroidism and Stress Urinary Incontinence: A Prospective Controlled Study. Med Bull Haseki. 2025;63(2):69-73. doi:10.4274/haseki.galenos.2025.04796.
• Luo Y, Zou P, Wang K, Li X, Wang J. Prevalence and Risk Factors of Urinary Incontinence Among Elderly Adults in Rural China: A Cross-Sectional Survey. J Wound Ostomy Continence Nurs. 2022;49(1):78-86. doi:10.1097/WON.0000000000000829
• Thabet A, Battecha K, Alayat M, et al. Prevalence of urinary incontinence among women in Saudi Arabia: a cross-sectional study. Eur Rev Med Pharmacol Sci. 2023;27(13):6040-6045. doi:10.26355/eurrev_202307_32958
• Subak LL, Richter HE, Hunskaar S. Obesity and urinary incontinence: epidemiology and clinical research update. J Urol. 2009;182(6 Suppl):S2-S7. doi:10.1016/j.juro.2009.08.071
• Hardy CC, Korstanje R. Aging and urinary control: Alterations in the brain-bladder axis. Aging Cell. 2023;22(12):e13990. doi:10.1111/acel.13990