A Rare Entity: Two Cases of Optic Nerve Glioma in Adults

Yıl 2025, Cilt: 5 Sayı: 1, 37 - 41, 30.04.2025

Kerem Kurt , Nuket Özkavruk Eliyatkın , Şeyda Uğurlu

Öz

Optic nerve gliomas are rare tumors that constitute the majority of optic pathway tumors and generally occur in the first two decades. They can seen anywhere along the optic pathway, with the optic nerve and chiasm being common sites. Most optic nerve gliomas are histologically classified as pilocytic astrocytomas, often associated with neurofibromatosis type 1. While typically presenting with visual impairment, other symptoms like optic atrophy and proptosis may also occur. Here, we report two cases of optic nerve glioma in elderly females aged 65 and 79 years, presenting with ocular pain and vision loss. Radiological and histopathological findings showed characteristic features of low-grade glioma. Immunohistochemical staining supported the diagnosis. We found 2 cases worth presenting because of the presence of prolonged symptoms and the advanced age of the patients.

Anahtar Kelimeler

optic nerve , optic nerve glioma , pilocytic astrocytoma

Nadir Bir Durum: Yetişkinlerde 2 Optik Sinir Gliomu Olgusu

Öz

Optik sinir gliomları, optik yolak tümorlerinin çoğunluğunu oluşturan genellikle hayatın ilk 2 yılında görülen nadir tümörlerdir. En sık optik sinirde olmakla beraber optik yolak boyunca yerleşebilir. Çoğu optik sinir gliomaları, genellikle nörofibromatozis tip 1 ile ilişkilendirilen pilositik astrositomalar olarak sınıflandırılmaktadır. Başlıca görme bozukluğu olmakla beraber optik atrofi ve proptoz gibi belirtiler de görülebilir. 65 ve 79 yaşında, sırasıyla göz ağrısı ve görme kaybı ile başvuran 2 kadın hastaya ait iki optik sinir glioma vakasını rapor ediyoruz. Radyolojik ve histopatolojik bulgular, düşük dereceli gliomun karakteristik özelliklerini göstermekle beraber immünohistokimyasal boyama da tanıyı desteklemiştir. Uzun süreli semptomların varlığı ve hastaların ileri yaşta olması sebebiyle 2 vakayı sunmaya değer bulduk.

Anahtar Kelimeler

optik sinir , optik sinir gliomu , pilositik astrositoma

Kaynakça

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