Araştırma Makalesi

Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models

Cilt: 8 Sayı: 1 30 Haziran 2021
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Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models

Öz

In recent years, the increase in obesity in the world has led to the development of new strategies in combating obesity. In the present study, it was aimed to investigate the effect of niacin and melatonin supplements to combat obesity in rats as a model organism. Treadmill exercise was performed on rats after niacin and melatonin supplementation for 10 days. In each group, weight loss was observed at the end of the 10 days exercise. In this study, it was observed that niacin supplementation leading to weight loss in rats that had treadmill exercise when compared to the control group. In addition, it was found that the weight loss observed in melatonin+niacin supplement was higher than niacin supplement only. It was found that the weight loss observed in the group given melatonin+niacin supplement was higher than the weight loss observed in niacin supplement only. As a result, niacin and melatonin supplementation can be recommended before exercise to combat obesity.

Anahtar Kelimeler

Kaynakça

  1. Borrell, L. N., & Samuel, L. (2014). Body mass index categories and mortality risk in US adults: the effect of overweight and obesity on advancing death. American Journal of Public Health, 104(3), 512–519. https://doi.org/10.2105/AJPH.2013.301597
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  3. Cantó, C., Houtkooper, R. H., Pirinen, E., Youn, D. Y., Oosterveer, M. H., Cen, Y., Fernandez-Marcos, P. J., Yamamoto, H., Andreux, P. A., Cettour-Rose, P., Gademann, K., Rinsch, C., Schoonjans, K., Sauve, A. A., & Auwerx, J. (2012). The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metabolism, 15(6), 838–847. https://doi.org/10.1016/j.cmet.2012.04.022
  4. Cantó, C., Menzies, K. J., & Auwerx, J. (2015). NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cell Metabolism, 22(1), 31–53. https://doi.org/10.1016/j.cmet.2015.05.023
  5. Cawley, J., & Meyerhoefer, C. (2012). The medical care costs of obesity: an instrumental variables approach. Journal of Health Economics, 31(1), 219–230. https://doi.org/10.1016/j.jhealeco.2011.10.003
  6. Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Academic press.
  7. Fernández Vázquez, G., Reiter, R. J., & Agil, A. (2018). Melatonin increases brown adipose tissue mass and function in Zücker diabetic fatty rats: implications for obesity control. Journal of Pineal Research, 64(4), e12472. https://doi.org/10.1111/jpi.12472
  8. Gronowska-Senger, A., Magdalena, G., & Katarzyna, K. (2009). Tocopherol acetate vs. oxidative stress induced by physical exercise in rats. Pol. J. Food Nutr. Sci., 59(3), 263–269. https://doi.org/10.2165/00128415-200510340-00041

Ayrıntılar

Birincil Dil

İngilizce

Konular

Çevre Bilimleri

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

30 Haziran 2021

Gönderilme Tarihi

7 Mayıs 2021

Kabul Tarihi

22 Haziran 2021

Yayımlandığı Sayı

Yıl 2021 Cilt: 8 Sayı: 1

Kaynak Göster

APA
Keskin, A., Aci, R., Duran, U., & Sugeçti, S. (2021). Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models. Caucasian Journal of Science, 8(1), 27-37. https://doi.org/10.48138/cjo.934158
AMA
1.Keskin A, Aci R, Duran U, Sugeçti S. Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models. Caucasian Journal of Science. 2021;8(1):27-37. doi:10.48138/cjo.934158
Chicago
Keskin, Adem, Recai Aci, Utku Duran, ve Serkan Sugeçti. 2021. “Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models”. Caucasian Journal of Science 8 (1): 27-37. https://doi.org/10.48138/cjo.934158.
EndNote
Keskin A, Aci R, Duran U, Sugeçti S (01 Haziran 2021) Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models. Caucasian Journal of Science 8 1 27–37.
IEEE
[1]A. Keskin, R. Aci, U. Duran, ve S. Sugeçti, “Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models”, Caucasian Journal of Science, c. 8, sy 1, ss. 27–37, Haz. 2021, doi: 10.48138/cjo.934158.
ISNAD
Keskin, Adem - Aci, Recai - Duran, Utku - Sugeçti, Serkan. “Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models”. Caucasian Journal of Science 8/1 (01 Haziran 2021): 27-37. https://doi.org/10.48138/cjo.934158.
JAMA
1.Keskin A, Aci R, Duran U, Sugeçti S. Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models. Caucasian Journal of Science. 2021;8:27–37.
MLA
Keskin, Adem, vd. “Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models”. Caucasian Journal of Science, c. 8, sy 1, Haziran 2021, ss. 27-37, doi:10.48138/cjo.934158.
Vancouver
1.Adem Keskin, Recai Aci, Utku Duran, Serkan Sugeçti. Physiological and Anti-obesity Effects of Melatonin and Niacin Supplements in Rat Models. Caucasian Journal of Science. 01 Haziran 2021;8(1):27-3. doi:10.48138/cjo.934158

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