SYNTHESİS OF URİDİNE DERIVATIVES

Yıl 1992, Cilt: 38 , 0 - 0, 01.01.1992

A. F. Sayed Ahmed

Öz

2', 3'-0 isopropylidene-5-ammomethyl uridine was condensed with some aldehydes. in the şame time, reduçtion 44in situ” of the reaction products was achieved Ncvçrtheless, the resulting compounds showed to be unstable during chromatographic processes. It was neces- sary, to increase their stability by suitable protection of their exo amino groups. On the other side, reactions concerhing both of 5-formyl uridine derivative with some halides, and 5-chlo- romethyl derivative of uridine with the previous aldehydes were also performed via Grignard reactions.

Anahtar Kelimeler

SYNTHESİS, DERIVATIVES, URİDİNE

Kaynakça

• SYNTHESİS OF URİDİNE DERIVATIVES SYNTHESİS OF URİDİNE DERIVATIVES