Investigation of asymptomatic COVID-19 carriers among healthcare workers
Öz
Purpose: The COVID-19 infection can lead to diverse clinical consequences, ranging from mild symptomatic cases to severe respiratory failure and potential fatality. Asymptomatic cases can also be seen and individuals who are considered to be asymptomatic can spread the disease. This study aims to determine the prevalence of COVID-19 asymptomatic cases among healthcare workers.
Material and Method: A total of 320 oropharyngeal samples were collected from individuals who are considered to be asymptomatic. The samples were then subjected to Reverse Transcription Polymerase Chain Reaction (RT-PCR) for SARS-CoV-2 detection
Results: A total of 320 healthcare workers volunteered to participate. Healthcare workers showing clinical symptoms suggestive of COVID-19 were excluded from participation in this study. Among the participants, 45% were doctors, 13.75% were nurses, and 12.5% were intern doctors. The gender distribution was 60% male and 40% female. Additionally, 52.8% (169 participants) reported a history of prior COVID-19 infection. All of the 320 participant’s samples were tested with RT-PCR found to be negative.
Conclusion: During this exit period from strict quarantine measures, it is crucial to prevent silent infection among asymptomatic carriers in addition to identifying and isolating the COVID-19 positive individuals
Anahtar Kelimeler
Proje Numarası
2023/270
Teşekkür
Special thanks to our study group: Kurtuluş O., Nayman A.H., Uran I., Doğan B.F., Dallıoğlu E, Paçacı M.C., Şenödeyeci E.; and thanks to Güdücüoğlu D., Şenödeyici D. for their support to the Project
Kaynakça
- Bai Y, Yao L, Wei T, Tian F, Jin DY, Chen L et al. Presumed asymptomatic carrier transmission of COVID-19. JAMA. 2020;323:1406-7.
- Kumar N, Shahul Hameed SK, Babu GR, Venkataswamy MM, Dinesh P, Kumar Bg P et al.. Descriptive epidemiology of SARS-CoV-2 infection in Karnataka state, South India: Transmission dynamics of symptomatic vs. asymptomatic infections. EClinicalMedicine. 2021;32:100717.7.
- Meng H, Xiong R, He R, Lin W, Hao B, Zhang L et al. CT imaging and clinical course of asymptomatic cases with COVID-19 pneumonia at admission in Wuhan, China. J Infect. 2020;81:e33-9.
- Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497-506.
- Joseph A. We don’t actually have that answeryet’: WHO clarifies comments on asymptomatic spread of Covid-19 https://www.statnews.com/2020/06/09/who-comments-asymptomatic-spread-covid-19/ (Accessed 14.07.2024).
- Ducharme J. Unpacking the new WHO controversy over asymptomatic COVID-19 transmission. Time, 09.06.2020.
- WHO. Transmission of COVID-19 by asymptomatic cases. http:// www.emro.who.int/health-topics/corona-virus/transmission-of-covid-19-byasymptomatic-cases.html.http://www.emro.who.int/health-topics/corona-virus/. ( Accessed 14.07.2024).
- Gandhi M, Yokoe DS, Havlir DV. Asymptomatic transmission, the Achilles' heel of current strategies to control Covid-19. N Engl J Med. 2020;382:2158-60.
- Jones N, Carver C. Are Interventions Such As Social Distancing Effective at Reducing the Risk of Asymptomatic Healthcare Workers Transmitting COVID-19 Infection to Other Household Members? Oxford, CEBM Oxford COVID-19 Evidence Service, 2020.
- CDC COVID-19 Response Team. Characteristics of health care personnel with COVID-19 - United States, February 12-April 9, 2020. MMWR Morb Mortal Wkly Rep. 2020;69:477-81.