Endometriozis tanısı almış infertil hastalarda D vitamin düzeyinin değerlendirilmesi

Year 2020, Volume: 45 Issue: 4, 1672 - 1678, 27.12.2020

Berin Bayat Bekir Kahveci , Ghanim Khatib , İbrahim Ürünsak , Yılmaz Atay

Abstract

Amaç: Bu çalışmanın amacı endometriozisi olan infertil hastalarda, endometirozis ve D vitamin düzeyi arasındaki ilişkiyi değerlendirmektir.
Gereç ve Yöntem: Çalışma grubunu, endometriozisi olan infertil hastalar, kontrol grubunu ise endometriozis dışı infertilite nedeni olan hastalar oluşturmaktadır. Çalışma grubuna sadece histopatolojik endometriozis tanısı bulunan hastalar dikkate alınmıştır. Hastaların yaşı, vücut kitle indeksi, infertilite süresi, ilk adet yaşı, sigara içme geçmişi, infertilite faktörü ve gebelik öyküsü ve anti-müllerian hormon düzeyleri gibi sosyodemografik ve klinik özellikleri ile laboratuvar değerleri ünitemizin kayıtlarından elde edildi.
Bulgular: Çalışmaya toplam 100 hasta dahil edildi. Çalışma ve kontrol gruplarında D vitamini düzeyleri karşılaştırıldığında, sırasıyla; 12,0 ± 8,6 ng/mL karşılık 14,7 ± 10,6 ng/mL ve AMH düzeyleri karşılaştırıldığında, sırasıyla; 2,0 ± 1,8 ng/mL karşılık 2,6 ± 2,3 ng/mL olarak tespit edildi. Grupların alt grup analizlerinde, sadece yaş dilimine göre 15-25 yaş arası olan hastalarda D vitamini seviyeleri arasındaki fark anlamlı bulunmuştur (5,8 ± 2,4 ng/mL karşılık 15,0 ± 8,5 ng/mL;.
Sonuç: D vitamini eksikliği olan endometriozisli genç kadınlarda D vitamini takviyesi faydalı olabilir.

Keywords

D vitamini, infertilite, endometriozis

Supporting Institution

yok

Project Number

yok

Evaluation of vitamin D levels in infertile patients diagnosed with endometriosis

Abstract

Purpose: The aim of this study was to evaluate the relationship between endometriosis and vitamin D level in infertility patients with endometriosis.
Materials and Methods: The study group consisted of infertile patients with endometriosis, while the control group consisted of infertile patients with causes other than endometriosis. Only patients diagnosed with histopathological endometriosis were considered in the study group. The sociodemographic, clinical features and laboratory values of the patients such as age, body mass index, duration of infertility, first menstrual age, smoking history, infertility factor, gestational history and anti-mullerian hormone levels were obtained from unit records.
Results: Totally 100 patients were included in the study. When vitamin D levels were compared in the study and control groups, respectively; 12.0 ± 8.6 ng / mL versus 14.7 ± 10.6 ng / mL, and AMH levels were compared, respectively; It was determined as 2.0 ± 1.8 ng / mL versus 2.6 ± 2.3 ng / mL. In the sub-analysis of the groups, only the difference in vitamin D levels of patients aged 15-25 (5.8 ± 2.4 ng / mL versus 15.0 ± 8.5 ng / mL) was significantly different.
Conclusion: Using vitamin D supplements in young women with endometriosis who have vitamin D deficiency could be beneficial.

Keywords

vitamin D, endometriosis

Project Number

yok

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