Berrak hücreli renal hücreli karsinomun nadir görülen gastrointestinal sistem metastazları: iki olgu sunumu

Yıl 2022, Cilt: 47 Sayı: 1, 477 - 480, 31.03.2022

Şeyma Öztürk Selma Erdoğan Düzcü Gülşah Ünsal Kayar Çetin Boran

Öz

Berrak hücreli renal hücreli karsinom, renal hücreli karsinomun en sık görülen alt tipidir. Cerrahi tedavi sonrası hastaların yarısından azında metastaz gelişebilmektedir.En sık görülen metastaz bölgeleri akciğer,lenf nodları,kemik ve karaciğerdir.Nadir de olsa gastrointestinal sisteme de metastaz yapabilmektedir. Kliniğe en sık başvuru şikayeti gastrointestinal kanamaya bağlı gelişen anemidir.Bu çalışmada iki farklı olguda berrak hücreli renal hücreli karsinomun mide ve rektosigmoid kolona metastazı sunulmuştur.

Anahtar Kelimeler

berrak hücreli renal hücreli karsinom, gastrointestinal kanal, metastaz

Rare metastases of clear cell renal cell carcinoma to gastrointestinal tract: two case reports

Öz

Renal cell carcinoma (RCC) is among the most prevalent renal tumors in adults. Its most common subtype is the clear cell subtype. Despite radical nephrectomy, patients may experience recurrence and distant metastasis. Lymph node and distant metastases can also be expected in early-stage RCCs, and the metastasis risk increases by tumor size. Lung metastasis is considered important when it comes to the spread of the tumor to other organs. In this study, we presented two cases with rare gastrointestinal metastases of cRCC.

Anahtar Kelimeler

clear cell renal cell carcinoma, gastrointestinal tract, metastasis

Kaynakça

• Zheng G, Li H, Li J, Zhang X, Zhang Y, Wu X. Metastatic renal clear cell carcinoma to the rectum, lungs, ilium, and lymph nodes. Medicine. 2017;96:1-3.
• Subaşı Ö, Aziret M, Karaman K, Ercan M. Colonic metastasis of renal cell carcinoma following curative nephrectomy: A case report and review of the literature. Int J Surg Case Rep. 2019;65:152-5.
• Kibria R, Sharma K, Ali SA, Rao P. Upper gastrointestinal bleeding revealing the stomach metastases of renal cell carcinoma. J Gastrointest Cancer. 2009;40:51-4.
• Yamamoto D, Hamada Y, Okazaki S, Kawakami K, Kanzaki S, Yamamoto C et al. Metastatic gastric tumor from renal cell carcinoma. Gastric Cancer. 2009;12:170-3.
• Namikawa T, Hanazaki K. Clinicopathological features and treatment outcomes of metastatic tumors in the stomach. Surg Today. 2014;44:1392-9.
• Eslick GD, Kalantar JS. Gastric metastasis in renal cell carcinoma: A case report and systematic review. J Gastrointest Cancer. 2011;42:296-301.
• Mallik AA, Katchy KC. Clear cell adenocarcinoma of the rectum. Med Princ Pract. 2005;14:58-60.
• Finkelstein A, Levy GH, Hui P. Clear cell adenocarcinoma of the colon arising in the background of endometriosis: A case report and diagnostic approach. Lab Med. 2010;41:111-4.