Servikal distonili hastalarda sternokleidomastoid kasta kutanöz sessiz periyot değerlendirilmesi

Year 2023, Volume: 48 Issue: 2, 463 - 471, 02.07.2023

Hasan Hüseyin Kır , Betigül Yürüten Çorbacıoğlu , Osman Serhat Tokgöz

https://doi.org/10.17826/cumj.1240625

Abstract

Amaç: Bu çalışmada servikal distoni patofizyolojisinde rol oynaması muhtemel beyin sapı inhibitör internöronlarındaki değişikliklerin inhibitör bir refleks olan kutanöz sessiz periyot(SP) yöntemi ile incelenmesi amaçlandı.
Gereç ve Yöntem: Servikal distonisi olan 20 hasta ve 25 sağlıklı gönüllünün bilateral sternokleidomastoid (SCM) kaslarından yüzeyel elektrotlar kullanılarak SP latans ve interval değerleri elde edildi. Elde edilen SP parametreleri gruplar içinde ve gruplar arasında karşılaştırıldı. Ayrıca her iki grupta karşılıklı SCM'lerinin SP parametrelerinin grup içi korelasyon analizi yapılmıştır.
Bulgular: Çalışmaya katılan hastaların yaş ortalaması 49,3 ± 14,7, kontrol grubunun 48,0 ± 13,7 olup iki grup arasında yaş ve cinsiyet açısından istatistiksel olarak anlamlı bir fark saptanmadı. Grup içi ve gruplar arası SP parametreleri arasında anlamlı fark saptanmadı. Hem hasta hem de kontrol gruplarında bilateral SCM'lerin SP latansları arasında güçlü bir birey içi korelasyon vardı. Birey içi SP intervalleri arasındaki güçlü pozitif korelasyonun kontrol grubunda da devam ettiği, hasta grupta ise kaybolduğu gözlendi.
Sonuç: Distoni hastalarında yapılmış olan kutanöz SP çalışmalarının sonuçları oldukça farklıdır. Distoni grubunda bilateral SCM SP süreleri arasındaki korelasyon kaybı, distonide var olduğu düşünülen aranöronlar arası bağlantılardaki anormalliğin aslında bir düzen kaybı olabileceğini göstermektedir. Bu “düzensizlik”, distoni hastalarında kutanöz SP çalışmalarının sonuçlarındaki tutarsızlıkları açıklayabilir.

Keywords

Servikal Distoni, Aranöronlar, Elektromiyografi

Evaluation of sternocleidomastoid muscle cutaneous silent period in patients with cervical dystonia

Abstract

Purpose: The aim of this study to examine the in changes inhibitory interneurons of the brainstem, which are likely to be involved in pathophysiology of cervical dystonia, using the cutaneous silent period(SP) method which is an inhibitor reflex.
Materials and Methods: SP latency and interval values were obtained from bilateral sternocleidomastoid (SCM) muscles of individuals in 20 patients with cervical dystonia and 25 healthy volunteers using superficial electrodes. SP parameters obtained were compared within and between groups. Furthermore, intra-individual correlation analysis was performed for SP parameters from bilateral SCMs of the individuals in both groups.
Results: The mean age of the patients participating in the study was 49.3 ± 14.7, and the control group was 48.0 ± 13.7. There was no statistically significant difference between the two groups in terms of age and gender. No significant difference was found in the comparison of SP parameters both within and between groups. There was a strong intra-individual correlation between SP latencies of bilateral SCMs of both patient and control groups. It was determined that the strongly positive intra-individual correlation between SP intervals also continued in the control group, whereas at patient group disappeared.
Conclusion: The loss of correlation between bilateral SCM SP durations in the dystonia group indicates that the abnormality in interneuron connections, which is thought to be present in dystonia, may actually be a loss of order. This “disorganization” may explain the discrepancies in the results of cutaneous SP studies in dystonia patients.

Keywords

Cervical Dystonia, Interneurons, Electromyography

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