Psychosocial Problems Experienced by Patients Diagnosed with Substance-Induced Psychosis

Öz

Substance-induced psychosis (SIP) is a clinical condition in which psychotic symptoms occur during intoxication or withdrawal related to psychoactive substance use. Beyond psychotic symptoms, SIP may lead to significant psychosocial problems that affect individuals socially, within the family, at work, and in emotional and behavioural functioning. This review aims to comprehensively examine the psychosocial problems experienced by individuals diagnosed with SIP based on the available literature. Evidence indicates that these individuals commonly experience social isolation and withdrawal, stigma and exclusion, loss of roles and functioning within the family, unemployment and financial difficulties, difficulties in emotion regulation, hopelessness, aggression, depressive symptoms, and other behavioural problems. These problems negatively affect treatment adherence, overall functioning, and quality of life. Therefore, in addition to pharmacological treatment, psychosocial dimensions should be addressed in the management of SIP. In this process, psychiatric nurses should take an active role in assessment, supportive interventions, and continuity of care.

Anahtar Kelimeler

• psychosis
• substance-induced psychosis
• psychiatric nursing

Kaynakça

1. Bramness JG, Hjorthøj C, Niemelä S, Taipale H, Rognli EB. Discussing the concept of substance-induced psychosis (SIP). Psychol Med 2024;54(11):2852-2856. google scholar
2. World Health Organization. International statistical classification of diseases and related health problems. 10th rev. Geneva: World Health Organization; 2019. google scholar
3. American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-5™. 5th ed. Washington, DC: American Psychiatric Publishing; 2013. google scholar
4. Ricci V, Martinotti G, Maina G. Substance-induced psychosis: diagnostic challenges and phenomenological insights. Psychiatry Int 2024;5(4):759-772. google scholar
5. Abouzed M, Gabr A, Elsheikh M, et al. Transition rates to schizophrenia and effectiveness of early intervention in substance-induced and brief psychotic disorders: a randomized controlled trial. Sci Rep 2025;15:40386. google scholar
6. Öztürk O, Uluşahin A. Alkol ve madde kullanımına bağlı bozukluklar ve davranışsal bağımlılıklar. In: Öztürk O, Uluğ BD, editors. Ruh Sağlığı ve Bozuklukları. İstanbul: Bayt Yayınları; 2023. p.504-7. google scholar
7. Hobern B, Carrotte ER, Rehm IC, et al. Stigma toward people living with schizophrenia spectrum and substance use disorders: a scoping review. Int J Ment Health Addict 2025;23:4191-4213. google scholar
8. Selotole S, Temane A, Poggenpoel M. Family members’ experiences of caring for a relative with substance-induced psychosis disorder. Curationis 2022;45(1):1-9. google scholar

9. Fiorentini A, Cantù F, Crisanti C, Cereda G, Oldani L, Brambilla P. Substance-induced psychoses: an updated literature review. Front Psychiatry 2021;12:1-15. google scholar
10. Wearne TA, Cornish JL. A comparison of methamphetamine-induced psychosis and schizophrenia: a review of positive, negative, and cognitive symptomatology. Front Psychiatry 2018;9:1-15. google scholar
11. Fett AKJ, Hanssen E, Eemers M, Peters E, Shergill SS. Social isolation and psychosis: an investigation of social interactions and paranoia in daily life. Eur Arch Psychiatry Clin Neurosci 2022;272(1):119-127. google scholar
12. Beckmann D, Lowman KL, Nargiso J, McKowen J, Watt L, Yule AM. Substance-induced psychosis in youth. Child Adolesc Psychiatr Clin N Am 2020;29(1):131-143. google scholar
13. Harnish A, Corrigan P, Byrne T, Pinals DA, Rodrigues S, Smelson D. Substance use and mental health stigma in veterans with co-occurring disorders. J Dual Diagn 2016;12(3-4):238-243. google scholar
14. Gutkind S, Gorfinkel LR, Hasin DS. Prospective effects of loneliness on frequency of alcohol and marijuana use. Addict Behav 2022;124:1-5. google scholar
15. Parish CL, Feaster DJ, Pollack HA, et al. Health care provider stigma toward patients with substance use disorders: protocol for a nationally representative survey. JMIR Res Protoc 2023;12:1-17. google scholar
16. Hamidi S, Ebrahimi H, Vahidi M, Areshtanab HN. Internalized stigma and its association with hope, self-esteem, self-efficacy, and treatment adherence among outpatients with severe mental illness: a cross-sectional survey. Iran J Nurs Midwifery Res 2023;28(3):345-351. google scholar
17. van der Heijden H, Kikkert M, de Haan L, Segeren M, Molman S, Schirmbeck F, et al. The relationship between substance use and self-reported aspects of social functioning in patients with a psychotic disorder. Eur Psychiatry 2024;67(1):1-8. google scholar
18. Mostafa NE, Ibrahim N, El-Bilsha M. Quality of life among patients with substance-induced psychosis. Mansoura Nurs J 2023;10(2):325-331. google scholar
19. Brunette MF, Mueser KT. Psychosocial interventions for the long-term management of patients with severe mental illness and co-occurring substance use disorder. J Clin Psychiatry 2006;67(Suppl 7):10-17. google scholar
20. McCarthy JM, Foo CYS, Liew M, Bianchi EN, Sultana E, Weiss RD, Mueser KT. Substance use in early psychosis: mixed methods impact on family. J Dual Diagn 2025;21(4):296-305. google scholar
21. Jansen JL, Hao J, Bruggeman R, Simons CJP, Van der Pluijm M, Koerts J, Krabbendam L. Unmet financial needs of people with psychotic disorders: a cross-sectional study in people with psychotic disorders, parents, siblings, and controls. J Clin Med 2024;13(19):1-19. google scholar
22. Chen Y, Zhang L, Zhang S, Zhang J, Yu H, Li Q, et al. Prevalence and sociodemographic configurations of anxiety and depression among caregivers of individuals with mental illness: a meta-analysis and qualitative comparative analysis. J Affect Disord 2025;375:486-495. google scholar
23. Ellilä V, Taipale H, Tiihonen J, Mittendorfer-Rutz E, Niemelä S. Relapse in substance-induced psychosis and associated risk factors. A Nationwide register-linkage study from Sweden. Addiction 2025;120(7):1422-1430. google scholar
24. Hammarlund R, Crapanzano KA, Luce L, Mulligan L, Ward KM. Review of the effects of selfstigma and perceived social stigma on the treatment-seeking decisions of individuals with drug- and alcohol-use disorders. Subst Abuse Rehabil 2018;9:115-136. google scholar
25. Sampson D, Heinsch M, Geddes J, Velleman R, Velleman G, Teesson M, et al. ‘I no longer know that person’: experiences of families living with someone using crystal methamphetamine. Plos One 2023;18(4):1-15. google scholar
26. Monari EN, Booth R, Forchuk C, Csiernik R. Experience of family members of relatives with substance use disorders: an integrative literature review. Creat Nurs 2024;30(3):232-244. google scholar
27. Andersen NK, Smith CL, Gao CX, et al. Vocational functioning in young people accessing services for first-episode psychosis and ultra-high risk of psychosis: a longitudinal naturalistic cohort study. Aust N Z J Psychiatry 2024;58(10):875-884. google scholar
28. Bakken R, Lien L, Fauske H, Landheim AS. Education and employment status among young adults three years after entering residential substance use treatment: a longitudinal data-linkage study. J Subst Use 2023;30(1):1-7. google scholar
29. Jäckel D, Bechdolf A, Burkhardt E, et al. Efficacy of individual placement and support (IPS) on employment, education, and training in young adults with early psychosis: a randomized controlled trial. Brain Behav 2025;15(5):1-10. google scholar
30. Jeyapalan J, Sassi P, Mittendorfer-Rutz E, Tiihonen J, Taipale H, Niemelä S. Characteristics of incident substance-induced psychosis compared to first-episode psychotic disorders: a nationwide register-linkage study from Sweden. Schizophr Res 2024;264:526-533. google scholar
31. Fardone E, Montoya ID, Schackman BR, McCollister KE. Economic benefits of substance use disorder treatment: a systematic literature review of economic evaluation studies from 2003 to 2021. J Subst Use Addict Treat 2023;152:1-12. google scholar
32. Grattan RE, Tryon VL, Lara N, et al. Risk and resilience factors for youth homelessness in Western countries: a systematic review. Psychiatr Serv 2022;73(4):425-438. google scholar
33. Murrie B, Lappin J, Large M, Sara G. Transition of substance-induced, brief, and atypical psychoses to schizophrenia: a systematic review and meta-analysis. Schizophr Bull 2020;46(3):505-516. google scholar
34. Hunt GE, Large MM, Cleary M, Lai HMX, Saunders JB. Prevalence of comorbid substance use in schizophrenia spectrum disorders in community and clinical settings, 1990–2017: systematic review and meta-analysis. Drug Alcohol Depend 2018;191:234-258. google scholar
35. Stellern J, Xiao KB, Grennell E, et al. Emotion regulation in substance use disorders: a systematic review and meta-analysis. Addiction 2023;118(1):30-47. google scholar
36. Ludwig L, Werner D, Lincoln TM. The relevance of cognitive emotion regulation to psychotic symptoms: a systematic review and meta-analysis. Clin Psychol Rev 2019;72:1-23. google scholar
37. Chu RST, Ng CM, Chu SC, et al. Rate and correlates of self-stigma in adult patients with early psychosis. Front Psychiatry 2023;14:1-8. google scholar
38. Lamsma J, Cahn W, Fazel S. Use of illicit substances and violent behaviour in psychotic disorders: two nationwide case-control studies and meta-analyses. Psychol Med 2020;50(12):2028–2033. google scholar
39. Volavka J. Comorbid personality disorders and violent behavior in psychotic patients. Psychiatr Q 2014;85(1):65-78. google scholar
40. Onyeagba CC, Naibo AT, Adili-George CF, Isaiah US. Coping styles and relapse rates among patients with substance-induced psychotic disorders. Adv Res Med Health Sci 2025;3(2):103-120. google scholar
41. Nsatimba F, Sehularo L, Moagi M. Current nursing care of patients with dual diagnosis: a comprehensive literature review. BMC Nurs 2025;24:1-11. google scholar
42. Hartley S, Raphael J, Lovell K, Berry K. Effective nurse-patient relationships in mental health care: a systematic review of interventions to improve the therapeutic alliance. Int J Nurs Stud 2020;102:1-9. google scholar
43. Güleşen G, Dikeç G. The roles of psychiatric nurses in the social rehabilitation of individuals with substance use disorders. Int J Health Serv Res Policy 2024;9(3):274-283. google scholar
44. Mensah DK. Perspectives of psychiatric nurses on the stigmatization of mental healthcare in Ghana: a qualitative study. Front Public Health 2024;12:1-10. google scholar