Is there any relationship between triglyceride and hemogram indicesin insulin resistance ?

Yıl 2023, Cilt: 3 Sayı: 2, 62 - 66, 29.04.2023

Serap Çetiner , Özgür Okuturlar

https://doi.org/10.56016/dahudermj.1260289

Öz

Objective: We aimed to evaluate triglyceride (TG) level correlation with hemogram and biochemical parameters in non-diabetic but insulin-resistant and non-insulin-resistant obese patients.
Methods: Patients with diabetes, neurological, cardiac, and rheumatological diseases were excluded from the study. Statistical analysis was performed by recording the patients' hemogram and all biochemical parameters. The patients were divided into two groups. Patients with a HOMA-IR level below 2.7 in group 1 and patients with a HOMA-IR level above 2.7 in group 2.
Results: 70 patients were selected for our study. Twenty-four were assigned as those without insulin resistance and were named Group 1, and 46 of these patients were assigned as those with insulin resistance and were named Group 2. TG level was found to be lower in Group 1(80.05+32.17) compared to Group 2 (176.67+16.21) (p = 0.0001).
There was no significant correlation between TG level and hemogram parameters in group 1. In Group 2, TG level and hematocrit (r = 0.475; p = 0.001) showed a significant positive correlation, while platelet lymphocyte ratio (r = 0.474; p = 0.001) showed a significant negative correlation. In Group 2, TG and ferritin (r = 0.421; p = 0.004) showed a significant positive correlation.
Conclusion: In obese patients without diabetes, triglyceride levels were high in those with high insulin resistance. The significant correlation of triglyceride level with hct, PLR, and ferritin in insulin resistance reveals the importance of these parameters in the atherosclerotic process.

Anahtar Kelimeler

Insulin Resistance, Triglycerides, Hematocrit, Lymphocytes, Blood Platelets, Ferritin

Kaynakça

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