Yüzde Gelişen Malign Periferik Sinir Kılıfı Tümörü Olgusu

Öz

Malign periferik sinir kılıfı tümörleri, iğsi hücreli agresif tümörer olup, yumuşak doku sarkomlarının %10’luk kısmını oluştururlar. Yüz tutulumu nadir olup, tümörler sıklıkla ekstremite ve gövdede görülür. 75 yaşında erkek hasta sol yanak bölgesinde hızlı büyüyen kitle şikayeti ile kliniğimize başvurdu. Malign periferik sinir kılıfı tümörü tanısı konan hastaya geniş eksizyon ve serbest radial ön kol flebi ile rekonstrüksiyon uygulandı. İleri yaş hastalarda baş boyun kitlelerinin ayırıcı tanısında malign periferik sinir kılıfı tümörleri düşünülmelidir.

Anahtar Kelimeler

• Malign periferik sinir kılıfı tümörü,baş boyun kitleleri,serbest flep

Malignant Peripheral Nerve Sheath Tumour With Facial Involvement

Öz

Malignant peripheral nerve sheath tumours are agressive, spindle cell sarcomas which constitute 10% of all soft tissue sarcomas. Head and neck involment is rare compared with extremity and axial involvement. 75 years old male patients referred to our clinic with a fast growing mass located in the left malar region. Malignant peripheral nerve sheath tumour diagnosis was established and wide excision and reconstruction with free radial forearm flap was performed. In elderly patients with head and neck masses malignant peripheral nerve sheath tumours must be kept in mind in differantial diagnosis.

Anahtar Kelimeler

• Malignant peripheral nerve sheath tumour,head and neck masses,free flap

Kaynakça

1. Referans1 Nikumbh DB, Suryawanshi KH, Dravid NV, Patil TB, Rokade CM. Giant Sporadic Low Grade Malignant Peripheral Nerve Sheath (MPNST) of Left Thigh. J Clin Diagn Res 2013;7:1155-8
2. Referans2 Akhavan A, Moghimi M, Karimi-Zarchi M, Navabii H.Malignant peripheral nerve sheet tumour of cervix. BMJ Case Rep 2012;30 doi: 10.1136/bcr.02.2012.5864.
3. Referans3 Pabiszczak M, Woźniak A, Wierzbicka M, Leszczyoska M, Szyfter W. Diagnostic difficulties in the laryngeal malignant peripheral nerve sheath tumor (MPNST). Otolaryngol Pol 2004;58: 1133-6
4. Referans4 Ducatman BS, Scheithauer BW, Piepgras DG, Reiman HM, Ilstrup DM. Malignant peripheral nerve sheath tumors. A clinicopathologic study of 120 cases. Cancer 1986;57:2006-21.
5. Referans5 Sørensen SA, Mulvihill JJ, Nielsen A. Long-term follow-up of von Recklinghausen neurofibromatosis. Survival and malignant neoplasms. N Engl J Med 1986;314:1010-5.
6. Referans6 BS Ducatman, BW Scheithauer, DG Piepgras, HM Reiman. Malignant Peripheral Nerve Sheath Tumors. A Clinicopathologic Study of 120 Cases. Cancer 1986;57:2006-21.
7. Referans7 Kim DH, Murovic JA, Tiel RL, Moes G, Kline DG, A series of 397 peripheral neural sheath tumors: 30-year experience at Louisiana State University Health Sciences Center. J Neurosurg 2005;102: 246.
8. Referans8 Baehring JM, Betensky RA, Batchelor TT. Malignant peripheral nerve sheath tumor: the clinical spectrum and outcome of treatment. Neurology 2003;61: 696.