İlaca Bağlı Lupus,

Öz

Anahtar Kelimeler

• -

İlaca Bağlı Lupus,

Öz

İlaca bağlı lupus, suçlu ilacın kesilmesiyle klinik bulguların geri dönebildii, sistemik lupus eritematozun kendini sınırlayan bir formudur. En sık neden olan ilaçlar hidralazin ve prokainamiddir, bunları takiben klorpromazin, izoniazid, metildopa, penisilamin, kinidin ve sulfasalazin sık suçlanan ilaçlar arasındadır. Yeni biyolojik ajanların ve antisitokin tedavilerin gündemde olmasıyla birlikte ilaca bağlı lupus görülme sıklığı artmıştır. En sık görülen klinik bulgular; artralji, artrit, miyalji, serozit ve ateştir. Antihiston antikorları hastalarda çoğunlukla bulunmaktadır. İlaca bağlı lupusta, suçlu ilacın kesilmesi ile hastalık bulguları ortadan kalkmasına rağmen, bazen kısa dönem kortikosteroid tedavisine ihtiyaç olmaktadır

Anahtar Kelimeler

• İlaç, bağlı, lupus

Kaynakça

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