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INFERTILITY CASES IN PULMONARY MEDICINE DEPARTMENTS

Yıl 2018, Cilt: 32 Sayı: 3, 251 - 258, 15.12.2018

Öz

Herein, we present two cases of infertility who
were evaluated by urologists and gynecologists. The first case was a
33-year-old man with recurrent sinusitis and bronchiectasis since 10 years old,
and he was evaluated by an urologist due to infertility. He had cough, wheeze,
and sputum. On his physical examination, bilateral crackles and rhonchi were
detected. Bilateral diffuse bronchiectasis and hyperinflation were seen at
thoracic tomography, and changes consistent with chronic sinusitis were shown
on paranasal sinus tomography. He was treated with azithromycin, inhaled
tobramycin, and dornase-alpha. His complaints improved and no bacterium was
detected in the sputum culture. Our second case was a 28-year-old woman.
Granulomatous salpingitis was identified in the histopathological examination
of the excised hidropic left tuba. She had night 
sweats and pelvic pain. Bilateral
fibrotic apical parenchymal changes were seen in thoracic tomography. Genital
tuberculosis was diagnosed, and she received antituberculosis treatment. At two
months, night sweat and groin pain resolved.

Kaynakça

  • Liou TG, Rubenstein RC. Carrier screening, incidence of cystic fibrosis, and difficult decisions. JAMA 2009; 302:2595-2596.
  • Türk Toraks Derneği Kistik Fibrozis Tanı ve Tedavi Rehberi. Türk Toraks Dergisi 201;12:2.
  • Gadsby DC, Vergani P, Csanády L. The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature 2006; 440:477-483.
  • Boucher RC. Airway surface dehydration in cystic fibrosis: pathogenesis and therapy. Annu Rev Med 2007; 58:157-710.
  • Goss CH, Burns JL. Exacerbations in cystic fibrosis. 1: Epidemiology and pathogenesis. Thorax 2007; 62:360-367.
  • Harrison F. Microbial ecology of the cystic fibrosis lung. Microbiology 2007; 153:917-923.
  • Lyczak JB, Cannon CL, Pier GB. Lung infections associated with cystic fibrosis. Clin Microbiol Rev 2002; 15: 194-222.
  • Radpour R, Gourabi H, Dizaj AV, Holzgreve W, Zhong XY. Genetic investigations of CFTR mutations in congenital absence of vas deferens, uterus, and vagina as a cause of infertility. J Androl 2008; 29:506-513.
  • American College of Obstetricians and Gynecologists Committee on Genetics. ACOG Committee Opinion No. 486: Update on carrier screening for cystic fibrosis. Obstet Gynecol 2011; 117: 1028-1031.
  • Pratt VM, Caggana M, Bridges C, Buller AM, DiAntonio L, Highsmith WE, et al. Development of genomic reference materials for cystic fibrosis genetic testing. J Mol Diagn 2009; 11: 186-193.
  • Quinzii C, Castellani C. The cystic fibrosis transmembrane regulatör gene and male infertility. J Endocrinol Invest 2000; 23: 684-690.
  • Farrokh D, Layegh P, Afzalaghaee M, Mohammadi M, Fallah Rastegar Y. Hysterosalpingographic findings in women with genital tuberculosis. Iran J Reprod Med. 2015; 13: 297-304.
  • Akbulut S, Arikanoglu Z, Basbug M. Tubercular tuboovarian cystic mass mimicking acute appendicitis: a case report. J Med Case Reports 2011; 5: 363.
  • Kapoor R, Ansari MS, Mandhani A, Gulia A. Clinical presentation and diagnostic approach in cases of genitourinary tuberculosis. Indian J Urol 2008; 24: 401-405.
  • Tripathy SN, Tripathy SN. Infertility and pregnancy outcome in female genital tuberculosis. Int J Gynecol Obstet 2002; 76: 159-163.
  • Varma TR. Genital tuberculosis and subsequent fertility. Int J Gynaecol Obstet 1991; 35: 1-11.
  • Dam P, Shirazee HH, Goswami SK, Ghosh S, Ganesh A, Choudhary K, et al. Role of latent tuberculosis in repeated IVF failure in Indian clinical setting. Gynecol Obstet Invest 2006; 61: 223-227.
  • Gurbuz A, Karateke A, Kabaca C, Kir G, Cetingoz E. Peritoneal tuberculosis simulating advanced ovarian carcinoma: is clinical impression sufficient to administer neoadjuvant chemotherapy for advanced ovarian cancer? Int J Gynecol Cancer 2006; 16: 307-312.
  • Chavhan GB, Hira P, Rathod K, Zacharia TT, Chawla A, Badhe P, et al. Female genital tuberculosos: hysterosalpingographic appearances. Br J Radiol 2004; 77: 164-169.
  • Ahmadi F, Zafarani M, Shahrzad GS. Hysterosalpingographic appearance of female genital tract tuberculosis: Part 1 Fallopian tube. Int J Fertil Steril 2014; 7: 245-252.
  • Sharma JB, Pushparaj M, Roy KK, Neyaz Z, Gupta N, Jain SK, et al. Hysterosalpingographic findings in infertile women with genital tuberculosis. Int J Gynecol Obstet 2008; 101: 150-155.
  • Kulshrestha V, Kriplani A, Agarwal N, Singh UB, Rana T. Genital tuberculosis among infertile woman and fertility outcome after antitubercular therapy. Int J Gynecol Obstet 2011; 113: 229-234.
  • Sharma JB. Current Diagnosis and management of female genital tuberculosis. J Obstet Gynaecol India 2015; 65: 362-371.
  • Mala YM, Prasad R, Singh N, Baweja CP, Tripathi R, Yedla N. Role of laparoscopy in diagnosing genital tuberculosis in suspected women: A cross-sectional study from a tertiary care hospital in Northern India. Indian J Tuberc. 2018; 65(1): 23-29.

Göğüs hastalıkları kliniklerinde değerlendirilen infertilite olguları

Yıl 2018, Cilt: 32 Sayı: 3, 251 - 258, 15.12.2018

Öz

İnfertilite nedeni ile üroloji ve kadın
doğum klinikleri tarafından takip edilen iki farklı olgunun sunulması
amaçlanmıştır. İlk olgu 10 yaşından beri bronşektazi ve tekrarlayan sinüziti
olan, infertilite tedavisi gören 33 yaşında erkek hasta idi. Öksürük, hırıltı
ve balgam yakınması olan hastanın fizik bakısında yaygın raller ve ronküsler
saptandı. Toraks tomografisinde her iki akciğerde yaygın bronşektazi alanları,
havalanma artışı, paranazal sinüs tomografisinde sinüzit ile uyumlu
değişiklikler izlendi. İnhale tobramisin ve dornaz-alfa ile azitromisin
başlandı. Yakınmaları gerileyen hastanın balgam kültüründe herhangi bir üreme
saptanmadı. İkinci olgu yirmi sekiz yaşında kadın hasta idi. Eksize edilen sol
hidropik tuba dokusunun histopatolojik incelemesinde granülomatoz salpenjit
izlenmişti. Gece terlemesi ve kasıklarda ağrı yakınması vardı. Kontrastlı
toraks tomografisinde bilateral apikal sekel fibrotik değişiklikler izlendi.
Genital tüberküloz tanısı konulan hastanın antitüberküloz tedavinin ikinci ayında
gece terlemesi ve kasıklarda ağrı yakınması geriledi.

Kaynakça

  • Liou TG, Rubenstein RC. Carrier screening, incidence of cystic fibrosis, and difficult decisions. JAMA 2009; 302:2595-2596.
  • Türk Toraks Derneği Kistik Fibrozis Tanı ve Tedavi Rehberi. Türk Toraks Dergisi 201;12:2.
  • Gadsby DC, Vergani P, Csanády L. The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature 2006; 440:477-483.
  • Boucher RC. Airway surface dehydration in cystic fibrosis: pathogenesis and therapy. Annu Rev Med 2007; 58:157-710.
  • Goss CH, Burns JL. Exacerbations in cystic fibrosis. 1: Epidemiology and pathogenesis. Thorax 2007; 62:360-367.
  • Harrison F. Microbial ecology of the cystic fibrosis lung. Microbiology 2007; 153:917-923.
  • Lyczak JB, Cannon CL, Pier GB. Lung infections associated with cystic fibrosis. Clin Microbiol Rev 2002; 15: 194-222.
  • Radpour R, Gourabi H, Dizaj AV, Holzgreve W, Zhong XY. Genetic investigations of CFTR mutations in congenital absence of vas deferens, uterus, and vagina as a cause of infertility. J Androl 2008; 29:506-513.
  • American College of Obstetricians and Gynecologists Committee on Genetics. ACOG Committee Opinion No. 486: Update on carrier screening for cystic fibrosis. Obstet Gynecol 2011; 117: 1028-1031.
  • Pratt VM, Caggana M, Bridges C, Buller AM, DiAntonio L, Highsmith WE, et al. Development of genomic reference materials for cystic fibrosis genetic testing. J Mol Diagn 2009; 11: 186-193.
  • Quinzii C, Castellani C. The cystic fibrosis transmembrane regulatör gene and male infertility. J Endocrinol Invest 2000; 23: 684-690.
  • Farrokh D, Layegh P, Afzalaghaee M, Mohammadi M, Fallah Rastegar Y. Hysterosalpingographic findings in women with genital tuberculosis. Iran J Reprod Med. 2015; 13: 297-304.
  • Akbulut S, Arikanoglu Z, Basbug M. Tubercular tuboovarian cystic mass mimicking acute appendicitis: a case report. J Med Case Reports 2011; 5: 363.
  • Kapoor R, Ansari MS, Mandhani A, Gulia A. Clinical presentation and diagnostic approach in cases of genitourinary tuberculosis. Indian J Urol 2008; 24: 401-405.
  • Tripathy SN, Tripathy SN. Infertility and pregnancy outcome in female genital tuberculosis. Int J Gynecol Obstet 2002; 76: 159-163.
  • Varma TR. Genital tuberculosis and subsequent fertility. Int J Gynaecol Obstet 1991; 35: 1-11.
  • Dam P, Shirazee HH, Goswami SK, Ghosh S, Ganesh A, Choudhary K, et al. Role of latent tuberculosis in repeated IVF failure in Indian clinical setting. Gynecol Obstet Invest 2006; 61: 223-227.
  • Gurbuz A, Karateke A, Kabaca C, Kir G, Cetingoz E. Peritoneal tuberculosis simulating advanced ovarian carcinoma: is clinical impression sufficient to administer neoadjuvant chemotherapy for advanced ovarian cancer? Int J Gynecol Cancer 2006; 16: 307-312.
  • Chavhan GB, Hira P, Rathod K, Zacharia TT, Chawla A, Badhe P, et al. Female genital tuberculosos: hysterosalpingographic appearances. Br J Radiol 2004; 77: 164-169.
  • Ahmadi F, Zafarani M, Shahrzad GS. Hysterosalpingographic appearance of female genital tract tuberculosis: Part 1 Fallopian tube. Int J Fertil Steril 2014; 7: 245-252.
  • Sharma JB, Pushparaj M, Roy KK, Neyaz Z, Gupta N, Jain SK, et al. Hysterosalpingographic findings in infertile women with genital tuberculosis. Int J Gynecol Obstet 2008; 101: 150-155.
  • Kulshrestha V, Kriplani A, Agarwal N, Singh UB, Rana T. Genital tuberculosis among infertile woman and fertility outcome after antitubercular therapy. Int J Gynecol Obstet 2011; 113: 229-234.
  • Sharma JB. Current Diagnosis and management of female genital tuberculosis. J Obstet Gynaecol India 2015; 65: 362-371.
  • Mala YM, Prasad R, Singh N, Baweja CP, Tripathi R, Yedla N. Role of laparoscopy in diagnosing genital tuberculosis in suspected women: A cross-sectional study from a tertiary care hospital in Northern India. Indian J Tuberc. 2018; 65(1): 23-29.
Toplam 24 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Makaleler
Yazarlar

Sibel Doruk 0000-0003-1756-979X

Kemal Can Tertemiz

Sibel Keçeci Bu kişi benim

Yayımlanma Tarihi 15 Aralık 2018
Gönderilme Tarihi 3 Ocak 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 32 Sayı: 3

Kaynak Göster

Vancouver Doruk S, Tertemiz KC, Keçeci S. Göğüs hastalıkları kliniklerinde değerlendirilen infertilite olguları. DEU Tıp Derg. 2018;32(3):251-8.