BibTex RIS Kaynak Göster

Intestinal Perforation after Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case

Yıl 2016, Cilt: 43 Sayı: 1, - , 01.03.2016
https://doi.org/10.5798/diclemedj.0921.2016.01.0661

Öz

Bevacizumab is a monoclonal antibody which is targeting to vascular endothelial growth factor. It has been shown to be a promising drug on metastatic colorectal cancer and is combined with chemotherapeutic agents. One should be aware of serious complications even though bevacizumab is a well-tolerated drug. There are a few intestinal perforation cases that have been reported in the oncologic surgery literature related to the bevacizumab treatment. In this case report, we aimed to represent a 45 years old man who was diagnosed with intestinal perforation after bevacizumab treatment ten months after a metastatic colon cancer surgery.
Key words: Bevacizumab, intestinal perforation, metastatic colorectal cancer

Kaynakça

  • Shih T, Lindley C. Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies. Clin Ther 2006;28:1779- 1802.
  • Bernold DM, Sinicrope FA. Advances in chemotherapy for colorectal cancer. Clin Gastroenterol Hepatol 2006;4:808-821.
  • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-2342.
  • Chen HX, Mooney M, Boron M, et al. Phase II multicenter trial of bevacizumab plus fluorouracil and leucovorin in patients with advanced refractory colorectal cancer: an NCI Treatment Referral Center Trial TRC-0301. J Clin Oncol 2006; 24:3354-3360.
  • Jain RK. Normalizing tumor vasculature with antiangiogenic therapy: a new paradigm for combination therapy. Nat Med 2001;7:987-989.
  • Shord SS, Bressler LR, Tierney LA, et al. Understanding and managing the possible adverse effects associated with bevacizumab.
  • Am J Health Syst Pharm 2009; 66:999-1013.
  • Saif MW, Elfiky A, Salem RR. Gastrointestinal perforation due to bevacizumab in colorectal cancer. Ann Surg Oncol 2007;14:1860-869.
  • Badgwell BD, Camp ER, Feig B, et al. Management of evacizumab-associated bowel perforation: a case series and review of the literature. Ann Oncol 2008;19:577-582.
  • Scappaticci FA, Fehrenbacher L, Cartwright T, et al. Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab. J Surg Oncol 2005;91:173-180.
  • Choi YI, Lee SH, Ahn BK, et al. Intestinal perforation in colorectal cancers treated with bevacizumab (Avastin). Cancer Res Treat 2008;40:33-35.
Toplam 11 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Yazıları
Yazarlar

Durmuş Çetin Bu kişi benim

Ebubekir Gündeş Bu kişi benim

Ulaş Aday Bu kişi benim

Hüseyin Çiyiltepe Bu kişi benim

Kamuran Değer Bu kişi benim

Mustafa Duman Bu kişi benim

Yayımlanma Tarihi 1 Mart 2016
Gönderilme Tarihi 29 Mart 2016
Yayımlandığı Sayı Yıl 2016 Cilt: 43 Sayı: 1

Kaynak Göster

APA Çetin, D., Gündeş, E., Aday, U., Çiyiltepe, H., vd. (2016). Intestinal Perforation after Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case. Dicle Tıp Dergisi, 43(1). https://doi.org/10.5798/diclemedj.0921.2016.01.0661
AMA Çetin D, Gündeş E, Aday U, Çiyiltepe H, Değer K, Duman M. Intestinal Perforation after Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case. diclemedj. Mart 2016;43(1). doi:10.5798/diclemedj.0921.2016.01.0661
Chicago Çetin, Durmuş, Ebubekir Gündeş, Ulaş Aday, Hüseyin Çiyiltepe, Kamuran Değer, ve Mustafa Duman. “Intestinal Perforation After Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case”. Dicle Tıp Dergisi 43, sy. 1 (Mart 2016). https://doi.org/10.5798/diclemedj.0921.2016.01.0661.
EndNote Çetin D, Gündeş E, Aday U, Çiyiltepe H, Değer K, Duman M (01 Mart 2016) Intestinal Perforation after Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case. Dicle Tıp Dergisi 43 1
IEEE D. Çetin, E. Gündeş, U. Aday, H. Çiyiltepe, K. Değer, ve M. Duman, “Intestinal Perforation after Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case”, diclemedj, c. 43, sy. 1, 2016, doi: 10.5798/diclemedj.0921.2016.01.0661.
ISNAD Çetin, Durmuş vd. “Intestinal Perforation After Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case”. Dicle Tıp Dergisi 43/1 (Mart 2016). https://doi.org/10.5798/diclemedj.0921.2016.01.0661.
JAMA Çetin D, Gündeş E, Aday U, Çiyiltepe H, Değer K, Duman M. Intestinal Perforation after Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case. diclemedj. 2016;43. doi:10.5798/diclemedj.0921.2016.01.0661.
MLA Çetin, Durmuş vd. “Intestinal Perforation After Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case”. Dicle Tıp Dergisi, c. 43, sy. 1, 2016, doi:10.5798/diclemedj.0921.2016.01.0661.
Vancouver Çetin D, Gündeş E, Aday U, Çiyiltepe H, Değer K, Duman M. Intestinal Perforation after Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case. diclemedj. 2016;43(1).